NASDAQ$SNDX

Syndax Pharmaceuticals Inc · Q2 2021 earnings

Q2 2021 earnings · · Investor relations

Briefing

Syndax reported its financial results for the second quarter ended June 30, 2021 and provided a clinical and business update.

Syndax Pharmaceuticals reported a net loss of $22.9 million, or $0.44 per share, for the second quarter of 2021. The company's research and development expenses increased to $16.9 million, while general and administrative expenses decreased to $5.8 million. As of June 30, 2021, Syndax had cash, cash equivalents and short-term investments of $253.1 million.

  • Selected a go-forward dose for the pivotal Phase 2 portion of AUGMENT-101 based on favorable findings from the intermediate dose cohort
  • Initiating frontline combination of SNDX-5613 with venetoclax and azacitidine in the Beat® AML Master Clinical Trial
  • Enrollment ongoing in global pivotal AGAVE-201 trial of axatilimab in cGVHD; updated results from Phase 1/2 trial anticipated in 4Q21
  • FDA granted Fast Track Designation (FTD) to SNDX-5613 for the treatment of adult and pediatric patients with relapsed or refractory acute leukemias harboring a MLLr or NPM1 mutation

Headline financials

Total Revenue

$379K

Previous: $379K+0.0%
EPS (adj)

-$0.44

Previous: -$0.42-4.8%
R&D Expenses

$16.9M

No prior period
SG&A Expenses

$5.84M

No prior period
Free Cash Flow

-$22.9M

Previous: -$17.1M-34.3%
Net Income

-$22.9M

Previous: -$17.1M-34.3%
Operating Income

-$22.3M

Previous: -$16.6M-34.5%
Gross Profit

$0.00

Previous: $0.00
Cash & Equivalents

$68M

Previous: $53.6M+26.9%
Total Assets

$263M

Previous: $193M+36.6%
Stock-Based Comp

$3.24M

No prior period

Revenue & EPS history

Syndax · Revenue · Quarterly

$379K

Q2 2021+0%vs Q2 2020
Beat estimate in 10 of 16 quarters(63%)
ActualEstimate

Forward guidance

Syndax provided financial guidance for the third quarter and full year of 2021. Research and development expenses are expected to be $25 to $30 million for the third quarter and $90 to $100 million for the full year. Total operating expenses are expected to be $30 to $35 million for the third quarter and $110 to $120 million for the full year.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2021

Historical avgQ2 2021

+1.6%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.5%

Avg return

30 days after

60%

24 / 40 earnings

Positive

+15.1%

Q4 2019

Best reaction

-21.6%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.9%-2.6%-5.2%
Q4 2025+5.1%+4.6%+13.6%
Q3 2025+11.6%+9.3%+43.5%
Q1 2025-21.6%-21.1%-17.8%
Q4 2024-7.1%-13.3%-19.5%
Q3 2024+12.7%+15.2%-11.3%
Q2 2024-7.3%-12.3%-9.5%
Q1 2024-5.2%-9.5%-15.9%
Q4 2023-2.1%-2.7%-2.4%
Q3 2023+6.3%+5.0%+19.0%
Q2 2023-3.5%-10.9%-4.5%
Q1 2023+7.8%+5.0%+3.8%
Q4 2022+1.6%-0.1%-15.6%
Q3 2022-2.0%-2.2%+9.5%
Q2 2022+0.5%+0.5%-2.4%
Q1 2022-5.8%-12.3%+10.1%
Q4 2021+3.3%-2.2%+11.5%
Q3 2021+2.1%-0.9%+5.9%
Q2 2021+7.0%+11.2%+23.9%
Q1 2021+14.6%+18.5%+21.5%
Q4 2020+0.4%-2.8%-5.3%
Q3 2020+8.8%+20.4%+30.9%
Q2 2020+6.5%-0.9%+0.7%
Q1 2020-1.8%+3.2%-8.0%
Q4 2019+15.1%+22.8%-0.6%
Q3 2019-0.3%+0.3%+24.5%
Q2 2019+10.6%+8.6%-3.0%
Q1 2019+9.1%+6.1%+3.9%
Q4 2018-13.5%-11.1%-4.2%
Q3 2018+2.1%+5.9%-3.5%
Q2 2018+12.0%+6.7%+8.8%
Q1 2018+9.9%+1.5%-25.5%
Q4 2017-1.5%-0.6%+47.9%
Q3 2017-11.7%-10.1%-28.4%
Q2 2017-5.7%-1.5%+8.0%
Q1 2017-7.0%+4.7%+26.7%
Q4 2016+5.0%+1.0%+18.0%
Q3 2016+0.9%-4.9%-17.1%
Q2 2016+5.6%+5.5%+3.1%
Q1 2016-2.1%
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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