NASDAQ$SNDX

Syndax Pharmaceuticals Inc · Q2 2024 earnings

Q2 2024 earnings · · Investor relations

Briefing

Syndax reported financial results and provided a business update.

Syndax Pharmaceuticals reported its Q2 2024 financial results, highlighting the advancement of its pipeline and the upcoming PDUFA action dates for axatilimab and revumenib.

  • Axatilimab BLA in refractory chronic GVHD is under Priority Review with a PDUFA action date of August 28, 2024.
  • Revumenib NDA in R/R KMT2Ar acute leukemia is being reviewed under RTOR with a PDUFA action date of December 26, 2024.
  • Pivotal AUGMENT-101 topline data from the mNPM1 AML cohort is expected in 4Q24, with a potential sNDA filing in 1H25.
  • The Company expects research and development expenses to be $70 to $75 million and total operating expenses to be $105 to $110 million for the third quarter of 2024.

Headline financials

Total Revenue

$3.5M

Previous: $0.00
EPS

-$0.80

Previous: -$0.64-25.0%
R&D Expenses

$48.7M

Previous: $34.8M+40.0%
SG&A Expenses

$29.1M

Previous: $14.9M+94.9%
Total Operating Expenses

$77.7M

No prior period
Capital Expenditures

$0.00

No prior period
Free Cash Flow

-$68.1M

Previous: -$44.6M-52.6%
Net Income

-$68.1M

Previous: -$44.6M-52.6%
Operating Income

-$74.2M

Previous: -$49.7M-49.4%
Gross Profit

$0.00

Previous: $0.00
R&D Expense

$48.7M

No prior period
Stock-Based Comp

$9.9M

Previous: $8.07M+22.7%

Revenue & EPS history

Syndax · Revenue · Quarterly

$3.5M

Q2 2024
Beat estimate in 2 of 8 quarters(25%)
ActualEstimate

Forward guidance

Syndax provided financial guidance for the third quarter and full year of 2024.

Tailwinds

  • The Company continues to believe it has sufficient capital to fund its research, clinical development and commercial operations through 2026.

Headwinds

  • For the third quarter of 2024, the Company expects research and development expenses to be $70 to $75 million.
  • For the third quarter of 2024, the Company expects total operating expenses to be $105 to $110 million.
  • For the full year of 2024, the Company continues to expect research and development expenses to be $240 to $260 million.
  • For the full year of 2024, the Company continues to expect total operating expenses to be $355 to $375 million, which includes milestone payments that the Company expects to become due as well as an estimated $43 million in non-cash stock compensation expense.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2024

Historical avgQ2 2024

+1.6%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.5%

Avg return

30 days after

60%

24 / 40 earnings

Positive

+15.1%

Q4 2019

Best reaction

-21.6%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.9%-2.6%-5.2%
Q4 2025+5.1%+4.6%+13.6%
Q3 2025+11.6%+9.3%+43.5%
Q1 2025-21.6%-21.1%-17.8%
Q4 2024-7.1%-13.3%-19.5%
Q3 2024+12.7%+15.2%-11.3%
Q2 2024-7.3%-12.3%-9.5%
Q1 2024-5.2%-9.5%-15.9%
Q4 2023-2.1%-2.7%-2.4%
Q3 2023+6.3%+5.0%+19.0%
Q2 2023-3.5%-10.9%-4.5%
Q1 2023+7.8%+5.0%+3.8%
Q4 2022+1.6%-0.1%-15.6%
Q3 2022-2.0%-2.2%+9.5%
Q2 2022+0.5%+0.5%-2.4%
Q1 2022-5.8%-12.3%+10.1%
Q4 2021+3.3%-2.2%+11.5%
Q3 2021+2.1%-0.9%+5.9%
Q2 2021+7.0%+11.2%+23.9%
Q1 2021+14.6%+18.5%+21.5%
Q4 2020+0.4%-2.8%-5.3%
Q3 2020+8.8%+20.4%+30.9%
Q2 2020+6.5%-0.9%+0.7%
Q1 2020-1.8%+3.2%-8.0%
Q4 2019+15.1%+22.8%-0.6%
Q3 2019-0.3%+0.3%+24.5%
Q2 2019+10.6%+8.6%-3.0%
Q1 2019+9.1%+6.1%+3.9%
Q4 2018-13.5%-11.1%-4.2%
Q3 2018+2.1%+5.9%-3.5%
Q2 2018+12.0%+6.7%+8.8%
Q1 2018+9.9%+1.5%-25.5%
Q4 2017-1.5%-0.6%+47.9%
Q3 2017-11.7%-10.1%-28.4%
Q2 2017-5.7%-1.5%+8.0%
Q1 2017-7.0%+4.7%+26.7%
Q4 2016+5.0%+1.0%+18.0%
Q3 2016+0.9%-4.9%-17.1%
Q2 2016+5.6%+5.5%+3.1%
Q1 2016-2.1%
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013

Discussion

Share your read of this quarter. Sign-in carries your eToro identity.

Join the conversation

Sign in with eToro to post your read of this quarter and vote on others'.

Sign in with eToro