NASDAQ$RARE

Ultragenyx Pharmaceutical Inc. · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Ultragenyx reported Q4 2022 financial results with total revenue of $103.3 million, driven by Crysvita and Dojolvi sales, and provided 2023 revenue guidance.

Ultragenyx reported Q4 2022 total revenue of $103.3 million. The company reaffirmed its 2023 financial guidance, expecting total revenue between $425 million and $450 million and net cash used in operations to be less than $400 million.

  • Total revenue for Q4 2022 was $103.3 million.
  • Crysvita revenue in Ultragenyx territories was $74.6 million, including $66.9 million in North America collaboration revenue.
  • Dojolvi revenue was $16.4 million in Q4 2022.
  • Mepsevii revenue was $4.8 million in Q4 2022.

Headline financials

Total Revenue

$103M

Previous: $83.4M+23.9%
EPS (adj)

-$2.16

Previous: -$1.79-20.7%
Total Operating Expenses

$249M

Previous: $186M+33.9%
Capital Expenditures

$27M

Previous: $16M+68.1%
Free Cash Flow

-$117M

Previous: -$70.4M-66.7%
Net Income

-$152M

Previous: -$122M-24.0%
Operating Income

-$146M

Previous: -$103M-42.0%
Gross Profit

$103M

Previous: $83.4M+23.9%
Cash & Equivalents

$897M

Previous: $999M-10.2%
Total Assets

$1.55B

Previous: $1.52B+1.5%

Revenue & EPS history

Ultragenyx · Revenue · Quarterly

$103M

Q4 2022+23.9%vs Q4 2021
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Revenue by segment

Ultragenyx · $102M total across 3 segments · Q4 2022

  • Crysvita Revenue
    $80.7M+45.4%
  • Dojolvi Revenue
    $16.4M+38.8%
  • Mepsevii Revenue
    $4.8M+54.2%

Forward guidance

Ultragenyx reaffirms its financial guidance for the full year 2023.

Tailwinds

  • Total revenue in the range of $425 million to $450 million
  • Crysvita revenue in the range of $325 million to $340 million, including royalties in Europe and North America.
  • Dojolvi revenue in the range of $65 million to $75 million
  • Net Cash Used in Operations is expected to be less than $400 million
  • Phase 2/3 study dosing patients; Phase 2 enrollment complete, data expected in mid-2023

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-1.2%

Avg return

Earnings day

-0.5%

Avg return

5 days after

+0.1%

Avg return

30 days after

42%

20 / 48 earnings

Positive

+14.7%

Q1 2015

Best reaction

-18.9%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.8%+5.2%-12.5%
Q4 2025-12.7%-13.0%-9.2%
Q3 2025-1.5%-1.6%+12.1%
Q1 2025-4.8%+2.9%+6.0%
Q4 2024-2.4%+1.8%-9.6%
Q3 2024-1.1%-1.4%-7.3%
Q2 2024+12.1%+10.6%+26.1%
Q1 2024-1.3%-3.1%-7.3%
Q4 2023+7.1%+4.8%+3.7%
Q3 2023+7.7%+5.7%+11.4%
Q2 2023-11.1%-16.9%-10.8%
Q1 2023+9.0%+8.6%+17.4%
Q4 2022+10.2%+2.9%-12.8%
Q3 2022-9.0%-16.4%-4.2%
Q2 2022+4.9%+0.9%-2.6%
Q1 2022-18.9%-24.5%-27.5%
Q4 2021-2.5%-1.6%-12.5%
Q3 2021+0.0%-3.1%-8.0%
Q2 2021+4.9%+10.9%+24.8%
Q1 2021-0.5%+7.5%-11.4%
Q4 2020-10.1%-13.7%-24.1%
Q3 2020+4.1%+10.1%+31.3%
Q2 2020+2.5%+10.4%+12.4%
Q1 2020-2.4%+4.1%+8.1%
Q4 2019-2.8%-2.8%-31.1%
Q3 2019-7.9%-4.6%+5.0%
Q2 2019-7.6%-3.6%-9.6%
Q1 2019-8.0%-5.7%-15.4%
Q4 2018+6.8%+5.6%+21.9%
Q3 2018+0.9%-3.0%-6.4%
Q2 2018-9.5%-2.5%+6.8%
Q1 2018+6.1%+17.7%+42.3%
Q4 2017-1.7%+1.6%+9.0%
Q3 2017+3.2%-5.2%+7.7%
Q2 2017-5.4%-10.6%-27.4%
Q1 2017+2.0%+2.5%-5.1%
Q4 2016+0.2%+0.2%+10.2%
Q2 2016-2.2%+0.2%+2.5%
Q1 2016+0.6%
Q4 2015-0.7%
Q3 2015-6.1%
Q2 2015-3.8%
Q1 2015+14.7%
Q4 2014-7.2%
Q3 2014-4.2%
Q2 2014+1.9%
Q1 2014-8.5%
Q4 2013-8.4%
Q2 2013
Q1 2013
Q4 2012

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