NASDAQ$RARE

Ultragenyx Pharmaceutical Inc. · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Ultragenyx Pharmaceutical reported Q1 2025, revenue of $139.3M, a net loss of $85M, diluted EPS of ($0.95).

For Q1 2025, Ultragenyx Pharmaceutical reported revenue of $139.3M, a net loss of $85M, diluted EPS was ($0.95). The filing highlights segment performance, liquidity, and management commentary on the period.

  • Revenue $139.3M.
  • Net loss $85M.
  • Diluted EPS ($0.95).

Headline financials

Total Revenue

$139M

Previous: $109M+28.0%
EPS (adj)

-$0.95

Previous: -$2.03+53.2%
Total Operating Expenses

$282M

Previous: $274M+2.9%
Research and Development

$166M

Previous: $178M-7.1%
Selling, General and Administrative

$87.8M

Previous: $78.2M+12.3%
Non-cash Stock Based Compensation

$39.9M

Previous: $36.9M+8.1%
Net Cash Used in Operations

-$166M

No prior period
Capital Expenditures

-$1.32M

Previous: -$3.21M+58.8%
Net Income

-$151M

Previous: -$171M+11.5%
Operating Income

-$143M

Previous: -$165M+13.6%

Revenue & EPS history

Ultragenyx · Revenue · Quarterly

$139M

Q1 2025+28%vs Q1 2024
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Revenue by segment

Ultragenyx · $98.1M total across 4 segments · Q3 2023

  • Crysvita Revenue
    $74.9M+16.1%
  • Dojolvi Revenue
    $16.6M+24.7%
  • Mepsevii Revenue
    $5.63M-6.8%
  • Evkeeza Revenue
    $963K

Forward guidance

Management discusses operating priorities, capital allocation, and sector risks in the quarterly filing.

Tailwinds

  • Headline results and segment trends anchor the quarter.
  • Liquidity and balance-sheet capacity support operations.
  • Strategic initiatives outlined in MD&A.

Headwinds

  • Macro, rates, or input costs may pressure margins.
  • One-time items affect year-over-year comparability.
  • Execution risk on growth or restructuring plans.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-1.2%

Avg return

Earnings day

-0.5%

Avg return

5 days after

+0.1%

Avg return

30 days after

42%

20 / 48 earnings

Positive

+14.7%

Q1 2015

Best reaction

-18.9%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.8%+5.2%-12.5%
Q4 2025-12.7%-13.0%-9.2%
Q3 2025-1.5%-1.6%+12.1%
Q1 2025-4.8%+2.9%+6.0%
Q4 2024-2.4%+1.8%-9.6%
Q3 2024-1.1%-1.4%-7.3%
Q2 2024+12.1%+10.6%+26.1%
Q1 2024-1.3%-3.1%-7.3%
Q4 2023+7.1%+4.8%+3.7%
Q3 2023+7.7%+5.7%+11.4%
Q2 2023-11.1%-16.9%-10.8%
Q1 2023+9.0%+8.6%+17.4%
Q4 2022+10.2%+2.9%-12.8%
Q3 2022-9.0%-16.4%-4.2%
Q2 2022+4.9%+0.9%-2.6%
Q1 2022-18.9%-24.5%-27.5%
Q4 2021-2.5%-1.6%-12.5%
Q3 2021+0.0%-3.1%-8.0%
Q2 2021+4.9%+10.9%+24.8%
Q1 2021-0.5%+7.5%-11.4%
Q4 2020-10.1%-13.7%-24.1%
Q3 2020+4.1%+10.1%+31.3%
Q2 2020+2.5%+10.4%+12.4%
Q1 2020-2.4%+4.1%+8.1%
Q4 2019-2.8%-2.8%-31.1%
Q3 2019-7.9%-4.6%+5.0%
Q2 2019-7.6%-3.6%-9.6%
Q1 2019-8.0%-5.7%-15.4%
Q4 2018+6.8%+5.6%+21.9%
Q3 2018+0.9%-3.0%-6.4%
Q2 2018-9.5%-2.5%+6.8%
Q1 2018+6.1%+17.7%+42.3%
Q4 2017-1.7%+1.6%+9.0%
Q3 2017+3.2%-5.2%+7.7%
Q2 2017-5.4%-10.6%-27.4%
Q1 2017+2.0%+2.5%-5.1%
Q4 2016+0.2%+0.2%+10.2%
Q2 2016-2.2%+0.2%+2.5%
Q1 2016+0.6%
Q4 2015-0.7%
Q3 2015-6.1%
Q2 2015-3.8%
Q1 2015+14.7%
Q4 2014-7.2%
Q3 2014-4.2%
Q2 2014+1.9%
Q1 2014-8.5%
Q4 2013-8.4%
Q2 2013
Q1 2013
Q4 2012

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