NASDAQ$RARE
Ultragenyx Pharmaceutical Inc. · Q4 2021 earnings
Q4 2021 earnings · · Investor relations
Briefing
Ultragenyx reported Q4 2021 financial results and provided a corporate update.
Ultragenyx reported a total revenue of $83.4 million for Q4 2021. The company made significant progress across its early and late-stage clinical pipeline and is preparing for the launch of Evkeeza in Europe.
- Total revenue for Q4 2021 was $83.4 million.
- Crysvita revenue in Ultragenyx territories was $55.5 million, including $50.2 million in collaboration revenue in the North American profit share territory.
- Dojolvi product sales were $11.8 million.
- The company had a cash balance of approximately $1.0 billion at the end of 2021.
Headline financials
Revenue & EPS history
Ultragenyx · Revenue · Quarterly
$83.4M
Revenue by segment
Ultragenyx · $70.4M total across 3 segments · Q4 2021
- Crysvita Revenue$55.5M+37.3%78.8%
- Dojolvi Revenue$11.8M+84.8%16.8%
- Mepsevii Revenue$3.11M-15.9%4.4%
Forward guidance
Ultragenyx expects 2022 revenue for Crysvita in Ultragenyx territories to be between $250 million and $260 million and Dojolvi revenue to be between $55 million and $65 million.
Tailwinds
- 2022 revenue for Crysvita in Ultragenyx territories to be between $250 million and $260 million.
- Dojolvi revenue to be between $55 million and $65 million.
- Submission of reimbursement dossiers expected in European countries in 2022 for Evkeeza.
- Dosing in the Pivotal Phase 2/3 Orbit study for UX143 is expected to begin in the first half of 2022.
- Phase 3 eNH3ance study of DTX301 expected to initiate in first half of 2022.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2021
-1.2%
Avg return
Earnings day
-0.5%
Avg return
5 days after
+0.1%
Avg return
30 days after
42%
20 / 48 earnings
Positive
+14.7%
Q1 2015
Best reaction
-18.9%
Q1 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +3.8% | +5.2% | -12.5% | |
| Q4 2025 | -12.7% | -13.0% | -9.2% | |
| Q3 2025 | -1.5% | -1.6% | +12.1% | |
| Q1 2025 | -4.8% | +2.9% | +6.0% | |
| Q4 2024 | -2.4% | +1.8% | -9.6% | |
| Q3 2024 | -1.1% | -1.4% | -7.3% | |
| Q2 2024 | +12.1% | +10.6% | +26.1% | |
| Q1 2024 | -1.3% | -3.1% | -7.3% | |
| Q4 2023 | +7.1% | +4.8% | +3.7% | |
| Q3 2023 | +7.7% | +5.7% | +11.4% | |
| Q2 2023 | -11.1% | -16.9% | -10.8% | |
| Q1 2023 | +9.0% | +8.6% | +17.4% | |
| Q4 2022 | +10.2% | +2.9% | -12.8% | |
| Q3 2022 | -9.0% | -16.4% | -4.2% | |
| Q2 2022 | +4.9% | +0.9% | -2.6% | |
| Q1 2022 | -18.9% | -24.5% | -27.5% | |
| Q4 2021 | -2.5% | -1.6% | -12.5% | |
| Q3 2021 | +0.0% | -3.1% | -8.0% | |
| Q2 2021 | +4.9% | +10.9% | +24.8% | |
| Q1 2021 | -0.5% | +7.5% | -11.4% | |
| Q4 2020 | -10.1% | -13.7% | -24.1% | |
| Q3 2020 | +4.1% | +10.1% | +31.3% | |
| Q2 2020 | +2.5% | +10.4% | +12.4% | |
| Q1 2020 | -2.4% | +4.1% | +8.1% | |
| Q4 2019 | -2.8% | -2.8% | -31.1% | |
| Q3 2019 | -7.9% | -4.6% | +5.0% | |
| Q2 2019 | -7.6% | -3.6% | -9.6% | |
| Q1 2019 | -8.0% | -5.7% | -15.4% | |
| Q4 2018 | +6.8% | +5.6% | +21.9% | |
| Q3 2018 | +0.9% | -3.0% | -6.4% | |
| Q2 2018 | -9.5% | -2.5% | +6.8% | |
| Q1 2018 | +6.1% | +17.7% | +42.3% | |
| Q4 2017 | -1.7% | +1.6% | +9.0% | |
| Q3 2017 | +3.2% | -5.2% | +7.7% | |
| Q2 2017 | -5.4% | -10.6% | -27.4% | |
| Q1 2017 | +2.0% | +2.5% | -5.1% | |
| Q4 2016 | +0.2% | +0.2% | +10.2% | |
| Q2 2016 | -2.2% | +0.2% | +2.5% | |
| Q1 2016 | +0.6% | — | — | |
| Q4 2015 | -0.7% | — | — | |
| Q3 2015 | -6.1% | — | — | |
| Q2 2015 | -3.8% | — | — | |
| Q1 2015 | +14.7% | — | — | |
| Q4 2014 | -7.2% | — | — | |
| Q3 2014 | -4.2% | — | — | |
| Q2 2014 | +1.9% | — | — | |
| Q1 2014 | -8.5% | — | — | |
| Q4 2013 | -8.4% | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — | |
| Q4 2012 | — | — | — |
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