NASDAQ$RARE
Ultragenyx Pharmaceutical Inc. · Q2 2025 earnings
Q2 2025 earnings · · After market close · Investor relations
Briefing
Ultragenyx Pharmaceutical Inc. reported financial results for the second quarter of 2025.
Total revenues reached $166.5 million in Q2 2025, driven by product sales of $80.8 million and royalty revenue of $85.7 million. The company recorded a net loss of $115.0 million and an operating loss of $107.9 million. Cash and cash equivalents stood at $176.3 million with total assets of $1.3 billion as of June 30, 2025.
- Q2 2025 total revenues increased to $166.5 million from $147.0 million in Q2 2024, primarily due to higher product sales and royalties.
- Net loss narrowed to $115.0 million compared to $131.6 million in the prior year quarter.
- Product sales were led by Crysvita at $34.7 million, Dojolvi at $23.2 million, Evkeeza at $14.6 million, and Mepsevii at $8.3 million.
- Geographic revenue distribution showed North America contributing $102.9 million, Latin America $33.0 million, EMEA $26.4 million, and Asia-Pacific $4.2 million.
Headline financials
Revenue & EPS history
Ultragenyx · Revenue · Quarterly
$166M
Revenue by segment
Ultragenyx · $80.8M total across 4 segments · Q2 2025
- Crysvita product sales$34.7M—43.0%
- Dojolvi$23.2M—28.7%
- Evkeeza$14.6M—18.0%
- Mepsevii$8.31M—10.3%
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports
-1.2%
Avg return
Earnings day
-0.5%
Avg return
5 days after
+0.1%
Avg return
30 days after
42%
20 / 48 earnings
Positive
+14.7%
Q1 2015
Best reaction
-18.9%
Q1 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q2 2025 | — | — | — | |
| Q1 2026 | +3.8% | +5.2% | -12.5% | |
| Q4 2025 | -12.7% | -13.0% | -9.2% | |
| Q3 2025 | -1.5% | -1.6% | +12.1% | |
| Q1 2025 | -4.8% | +2.9% | +6.0% | |
| Q4 2024 | -2.4% | +1.8% | -9.6% | |
| Q3 2024 | -1.1% | -1.4% | -7.3% | |
| Q2 2024 | +12.1% | +10.6% | +26.1% | |
| Q1 2024 | -1.3% | -3.1% | -7.3% | |
| Q4 2023 | +7.1% | +4.8% | +3.7% | |
| Q3 2023 | +7.7% | +5.7% | +11.4% | |
| Q2 2023 | -11.1% | -16.9% | -10.8% | |
| Q1 2023 | +9.0% | +8.6% | +17.4% | |
| Q4 2022 | +10.2% | +2.9% | -12.8% | |
| Q3 2022 | -9.0% | -16.4% | -4.2% | |
| Q2 2022 | +4.9% | +0.9% | -2.6% | |
| Q1 2022 | -18.9% | -24.5% | -27.5% | |
| Q4 2021 | -2.5% | -1.6% | -12.5% | |
| Q3 2021 | +0.0% | -3.1% | -8.0% | |
| Q2 2021 | +4.9% | +10.9% | +24.8% | |
| Q1 2021 | -0.5% | +7.5% | -11.4% | |
| Q4 2020 | -10.1% | -13.7% | -24.1% | |
| Q3 2020 | +4.1% | +10.1% | +31.3% | |
| Q2 2020 | +2.5% | +10.4% | +12.4% | |
| Q1 2020 | -2.4% | +4.1% | +8.1% | |
| Q4 2019 | -2.8% | -2.8% | -31.1% | |
| Q3 2019 | -7.9% | -4.6% | +5.0% | |
| Q2 2019 | -7.6% | -3.6% | -9.6% | |
| Q1 2019 | -8.0% | -5.7% | -15.4% | |
| Q4 2018 | +6.8% | +5.6% | +21.9% | |
| Q3 2018 | +0.9% | -3.0% | -6.4% | |
| Q2 2018 | -9.5% | -2.5% | +6.8% | |
| Q1 2018 | +6.1% | +17.7% | +42.3% | |
| Q4 2017 | -1.7% | +1.6% | +9.0% | |
| Q3 2017 | +3.2% | -5.2% | +7.7% | |
| Q2 2017 | -5.4% | -10.6% | -27.4% | |
| Q1 2017 | +2.0% | +2.5% | -5.1% | |
| Q4 2016 | +0.2% | +0.2% | +10.2% | |
| Q2 2016 | -2.2% | +0.2% | +2.5% | |
| Q1 2016 | +0.6% | — | — | |
| Q4 2015 | -0.7% | — | — | |
| Q3 2015 | -6.1% | — | — | |
| Q2 2015 | -3.8% | — | — | |
| Q1 2015 | +14.7% | — | — | |
| Q4 2014 | -7.2% | — | — | |
| Q3 2014 | -4.2% | — | — | |
| Q2 2014 | +1.9% | — | — | |
| Q1 2014 | -8.5% | — | — | |
| Q4 2013 | -8.4% | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — | |
| Q4 2012 | — | — | — |
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