NASDAQ$PCVX

Vaxcyte Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Vaxcyte reported financial results for the first quarter ended March 31, 2023 and provided a business update.

Vaxcyte reported positive data from the Phase 2 study in adults aged 65 and older, confirming the clinical potential of VAX-24 and validating the carrier-sparing, cell-free platform. The company's balance sheet was further strengthened by a recent follow-on equity offering, allowing for expansion of manufacturing capabilities and advancement of the PCV franchise.

  • Reported positive data from Phase 2 study of VAX-24 in adults aged 65 and older, demonstrating robust immune responses across all 24 serotypes.
  • Completed a successful $575 million follow-on financing, strengthening the balance sheet.
  • Dosed first participants in infant Phase 2 study evaluating VAX-24 for the prevention of Invasive Pneumococcal Disease (IPD).
  • VAX-31 progressing with Adult Investigational New Drug (IND) application submission and subsequent clearance announcement expected in second half 2023 and Topline Phase 1/2 Data in 2024.

Headline financials

EPS (adj)

-$0.70

Previous: -$0.68-2.9%
R&D Expenses

$58.1M

Previous: $31.7M+83.3%
G&A Expenses

$13.1M

Previous: $7.5M+74.7%
Capital Expenditures

$5.61M

Previous: $2.92M+92.1%
Free Cash Flow

-$53.3M

Previous: -$30.6M-74.1%
Net Income

-$60.5M

Previous: -$39M-55.1%
Operating Income

-$71.2M

Previous: -$39.2M-81.5%
Cash & Equivalents

$950M

Previous: $352M+169.6%
Total Assets

$1.01B

Previous: $403M+150.3%
Stock-Based Comp

$9.65M

Previous: $4.1M+135.4%

Revenue & EPS history

Vaxcyte · Revenue · Quarterly

$0

Q4 2025

Forward guidance

Vaxcyte is advancing the clinical development of its PCV programs with several anticipated key upcoming milestones.

Tailwinds

  • End-of-Phase 2 meeting with the FDA in the second half of 2023 to inform the conduct of the adult Phase 3 program.
  • Topline safety, tolerability and immunogenicity data from the Phase 3 pivotal non-inferiority study in adults in 2025.
  • Topline safety, tolerability and immunogenicity data from the primary three-dose immunization series of the infant Phase 2 study by 2025, followed by topline data from the booster dose approximately nine months later.
  • Submission of the adult IND application to the FDA and announcement of subsequent FDA clearance in the second half of 2023.
  • Topline safety, tolerability and immunogenicity data from the Phase 1/2 study in adults in 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+0.6%

Avg return

Earnings day

+0.8%

Avg return

5 days after

-0.2%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+23.8%

Q2 2020

Best reaction

-21.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+2.7%+1.0%-13.3%
Q3 2025-2.5%+3.8%+12.4%
Q2 2025-9.1%-9.1%+0.1%
Q1 2025+8.3%+3.6%+27.6%
Q4 2024-0.9%-9.1%-12.5%
Q3 2024-2.3%+0.2%-15.4%
Q1 2024-2.9%-2.7%+5.1%
Q4 2023-4.9%-9.2%-13.5%
Q3 2023-1.0%-5.1%+10.8%
Q2 2023-2.5%-2.0%+3.4%
Q1 2023+3.7%-3.7%-0.3%
Q4 2022-1.8%+2.0%-11.6%
Q3 2022+4.2%+3.3%+0.6%
Q2 2022+0.4%+1.7%+6.1%
Q1 2022-11.4%-3.0%-14.8%
Q4 2021+5.5%+1.5%+6.5%
Q3 2021+3.4%+4.7%-12.7%
Q2 2021+5.1%+3.6%+3.1%
Q1 2021+13.5%+17.0%+40.5%
Q4 2020-21.5%-11.9%-17.3%
Q3 2020+3.9%-0.2%-15.3%
Q2 2020+23.8%+31.0%+5.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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