NASDAQ$PCVX

Vaxcyte Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Vaxcyte reported financial results for the third quarter ended September 30, 2021 and provided a business update.

Vaxcyte reported a net loss of $26.6 million for the third quarter of 2021. The company's cash, cash equivalents and investments were $318.3 million as of September 30, 2021. Vaxcyte expects to submit the VAX-24 IND application to the FDA in the first quarter of 2022.

  • Advanced VAX-24 Investigational New Drug (IND)-Enabling Activities, completing manufacture of GMP drug product and GLP toxicology study.
  • Presented Preclinical Data Supporting the Potential of VAX-XP, showing conjugate-like immune responses for all 31 serotypes.
  • Initiated VAX-A1 IND-Enabling Activities, advancing development of a novel conjugate vaccine designed to prevent infections caused by Group A Streptococcus pyogenes (Strep) bacteria.
  • Enhanced Board of Directors with Appointment of Four Industry Veterans and appointed Harp Dhaliwal as Senior Vice President, Commercial Manufacturing & Supply Chain.

Headline financials

EPS (adj)

-$0.51

Previous: -$0.41-24.4%
R&D Expenses

$20.4M

Previous: $16.4M+24.5%
G&A Expenses

$6.52M

Previous: $4.9M+33.2%
Capital Expenditures

$1.72M

No prior period
Free Cash Flow

-$30.1M

No prior period
Net Income

-$26.6M

Previous: -$21M-26.6%
Operating Income

-$27M

No prior period
Cash & Equivalents

$318M

Previous: $397M-19.8%
Total Assets

$354M

Previous: $404M-12.3%
Stock-Based Comp

$2.94M

No prior period

Revenue & EPS history

Vaxcyte · Revenue · Quarterly

$0

Q4 2025

Forward guidance

The Company currently expects to submit the VAX-24 IND application to the FDA in the first quarter of 2022 and anticipates announcing topline data from the ensuing Phase 1/2 clinical proof-of-concept study in adults between late 2022 and early 2023.

Tailwinds

  • VAX-24: The Company currently expects to submit the VAX-24 IND application to the FDA in the first quarter of 2022
  • Following the anticipated completion of the remaining drug product testing and release, as well as documentation of stability.
  • Vaxcyte continues to anticipate announcing topline data from the ensuing Phase 1/2 clinical proof-of-concept study in adults between late 2022 and early 2023.
  • Vaxcyte expects to nominate a final vaccine candidate for VAX-PG, its novel therapeutic vaccine designed to treat periodontal disease, in the first half of 2022.
  • Following the nomination of its final VAX-A1 vaccine candidate in the first quarter of 2021, the Company initiated IND-enabling studies in the second half of 2021, consistent with prior guidance.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

+0.6%

Avg return

Earnings day

+0.8%

Avg return

5 days after

-0.2%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+23.8%

Q2 2020

Best reaction

-21.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+2.7%+1.0%-13.3%
Q3 2025-2.5%+3.8%+12.4%
Q2 2025-9.1%-9.1%+0.1%
Q1 2025+8.3%+3.6%+27.6%
Q4 2024-0.9%-9.1%-12.5%
Q3 2024-2.3%+0.2%-15.4%
Q1 2024-2.9%-2.7%+5.1%
Q4 2023-4.9%-9.2%-13.5%
Q3 2023-1.0%-5.1%+10.8%
Q2 2023-2.5%-2.0%+3.4%
Q1 2023+3.7%-3.7%-0.3%
Q4 2022-1.8%+2.0%-11.6%
Q3 2022+4.2%+3.3%+0.6%
Q2 2022+0.4%+1.7%+6.1%
Q1 2022-11.4%-3.0%-14.8%
Q4 2021+5.5%+1.5%+6.5%
Q3 2021+3.4%+4.7%-12.7%
Q2 2021+5.1%+3.6%+3.1%
Q1 2021+13.5%+17.0%+40.5%
Q4 2020-21.5%-11.9%-17.3%
Q3 2020+3.9%-0.2%-15.3%
Q2 2020+23.8%+31.0%+5.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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