NASDAQ$PCVX

Vaxcyte Inc · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Vaxcyte reported Q1 2025 a net loss of $140.7M, diluted EPS of $(1.04).

For Q1 2025, Vaxcyte reported net loss was $140.7M, diluted EPS was $-1.04. Management discusses operating trends, liquidity, and outlook in the quarterly filing.

  • Net loss $140.7M.
  • Diluted EPS $-1.04.
  • MD&A highlights operating priorities, liquidity, and sector-specific risks.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$1.04

Previous: -$0.85-22.4%
R&D Expenses

$148M

Previous: $94.6M+56.6%
G&A Expenses

$32.7M

Previous: $19.9M+64.2%
Interest Income

$32.9M

Previous: $21.7M+52.0%
Stock-Based Comp

$30.6M

Previous: $17.6M+73.7%
Net Income

-$141M

Previous: -$95M-48.1%
Operating Income

-$181M

Previous: -$114M-57.9%

Revenue & EPS history

Vaxcyte · Revenue · Quarterly

$0

Q1 2025

Forward guidance

Biotech outlook centers on trial milestones, partnerships, and cash runway.

Tailwinds

  • Pipeline progress and collaboration optionality.
  • Cash resources to fund R&D.

Headwinds

  • Clinical and regulatory risk.
  • Operating losses until commercial scale.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.6%

Avg return

Earnings day

+0.8%

Avg return

5 days after

-0.2%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+23.8%

Q2 2020

Best reaction

-21.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+2.7%+1.0%-13.3%
Q3 2025-2.5%+3.8%+12.4%
Q2 2025-9.1%-9.1%+0.1%
Q1 2025+8.3%+3.6%+27.6%
Q4 2024-0.9%-9.1%-12.5%
Q3 2024-2.3%+0.2%-15.4%
Q1 2024-2.9%-2.7%+5.1%
Q4 2023-4.9%-9.2%-13.5%
Q3 2023-1.0%-5.1%+10.8%
Q2 2023-2.5%-2.0%+3.4%
Q1 2023+3.7%-3.7%-0.3%
Q4 2022-1.8%+2.0%-11.6%
Q3 2022+4.2%+3.3%+0.6%
Q2 2022+0.4%+1.7%+6.1%
Q1 2022-11.4%-3.0%-14.8%
Q4 2021+5.5%+1.5%+6.5%
Q3 2021+3.4%+4.7%-12.7%
Q2 2021+5.1%+3.6%+3.1%
Q1 2021+13.5%+17.0%+40.5%
Q4 2020-21.5%-11.9%-17.3%
Q3 2020+3.9%-0.2%-15.3%
Q2 2020+23.8%+31.0%+5.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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