NASDAQ$PCVX

Vaxcyte Inc · Q1 2021 earnings

Q1 2021 earnings · · Investor relations

Briefing

Vaxcyte reported financial results for the first quarter of 2021 and provided a business update.

Vaxcyte is advancing its VAX-24 program towards IND submission and has made progress on its pipeline vaccines, VAX-XP and VAX-A1. The company's cash, cash equivalents, and investments totaled $370.9 million as of March 31, 2021.

  • Advanced VAX-24 IND-enabling activities, making progress toward completion of GMP conjugated drug substances.
  • Published new research supporting VAX-24 and Vaxcyte’s technology platform, demonstrating robust immune responses in preclinical studies.
  • Appointed Janet Graesser as Vice President of Corporate Communications and Investor Relations.
  • Reaffirmed guidance for pipeline programs, including VAX-24 IND submission expected between January and June 2022.

Headline financials

EPS (adj)

-$0.41

Previous: -$0.58+29.4%
R&D Expenses

$17.3M

Previous: $24.3M-29.0%
G&A Expenses

$5.89M

Previous: $3.28M+79.4%
Net Income

-$21.2M

Previous: -$27.1M+21.8%
Cash & Equivalents

$371M

No prior period
Total Assets

$382M

No prior period

Revenue & EPS history

Vaxcyte · Revenue · Quarterly

$0

Q4 2025

Forward guidance

Vaxcyte reaffirmed its previously issued guidance for its pipeline programs.

Tailwinds

  • VAX-24: Vaxcyte expects to submit an IND application for VAX-24 to the FDA between January and June 2022.
  • VAX-24: Vaxcyte expects to announce topline data from the ensuing Phase 1/2 clinical proof-of-concept study between late 2022 and early 2023.
  • VAX-A1: Following the nomination of its final vaccine candidate for VAX-A1 in the first quarter of 2021, Vaxcyte plans to initiate IND-enabling studies in the second half of 2021.
  • VAX-PG: Vaxcyte expects to nominate a final vaccine candidate for VAX-PG, its novel therapeutic vaccine designed to treat periodontal disease, in the second half of 2021.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2021

Historical avgQ1 2021

+0.6%

Avg return

Earnings day

+0.8%

Avg return

5 days after

-0.2%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+23.8%

Q2 2020

Best reaction

-21.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+2.7%+1.0%-13.3%
Q3 2025-2.5%+3.8%+12.4%
Q2 2025-9.1%-9.1%+0.1%
Q1 2025+8.3%+3.6%+27.6%
Q4 2024-0.9%-9.1%-12.5%
Q3 2024-2.3%+0.2%-15.4%
Q1 2024-2.9%-2.7%+5.1%
Q4 2023-4.9%-9.2%-13.5%
Q3 2023-1.0%-5.1%+10.8%
Q2 2023-2.5%-2.0%+3.4%
Q1 2023+3.7%-3.7%-0.3%
Q4 2022-1.8%+2.0%-11.6%
Q3 2022+4.2%+3.3%+0.6%
Q2 2022+0.4%+1.7%+6.1%
Q1 2022-11.4%-3.0%-14.8%
Q4 2021+5.5%+1.5%+6.5%
Q3 2021+3.4%+4.7%-12.7%
Q2 2021+5.1%+3.6%+3.1%
Q1 2021+13.5%+17.0%+40.5%
Q4 2020-21.5%-11.9%-17.3%
Q3 2020+3.9%-0.2%-15.3%
Q2 2020+23.8%+31.0%+5.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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