NASDAQ$PBYI

Puma Biotechnology Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

Puma Biotechnology reported Q3 2025, revenue of $14.5M, net loss of $8M.

For Q3 2025, Puma Biotechnology reported revenue of $14.5M, a net loss of $8M. Management discusses segment performance, capital allocation, and outlook in the earnings filing.

  • Revenue $14.5M.
  • Net loss $8M.
  • Puma Biotechnology highlights liquidity, operations, and 2026 priorities.

Headline financials

Total Revenue

$54.5M

Previous: $80.5M-32.4%
EPS (adj)

$0.21

Previous: $0.41-48.8%
Operating Cash Flow

$9.7M

Previous: $11M-11.8%
SG&A Expenses

$16.8M

Previous: $16.8M+0.0%
R&D Expenses

$15.9M

Previous: $12.5M+27.2%
Total Operating Expenses

$44.9M

Previous: $58.4M-23.1%
Interest Income

$1M

Previous: $1.3M-23.1%
Interest Expense

$1.5M

Previous: $3.1M-51.6%
Income Tax Expense

$400K

Previous: $300K+33.3%
Total Cash and Securities

$94.4M

No prior period
Capital Expenditures

-$107K

Previous: -$40K-167.5%
Net Income

$8.84M

Previous: $20.3M-56.5%
Operating Income

$9.6M

Previous: $22.1M-56.5%

Revenue & EPS history

Puma Biotechnology · Revenue · Quarterly

$54.5M

Q3 2025-32.4%vs Q3 2024
Beat estimate in 13 of 14 quarters(93%)
ActualEstimate

Revenue by segment

Puma Biotechnology · $56.1M total across 2 segments · Q3 2023

  • Product Revenue, Net
    $51.6M
  • Royalty Revenue
    $4.5M+60.7%

Forward guidance

The release discusses Puma Biotechnology's outlook for upcoming periods, including capital allocation, operating priorities, and market risks, without relying solely on numeric EPS bridges.

Tailwinds

  • Puma Biotechnology cites operational execution and demand trends supporting the outlook.
  • Balance sheet and liquidity actions aim to fund growth and returns.

Headwinds

  • GAAP profitability remained under pressure in Q3 2025.
  • Macro, pricing, and input-cost volatility could pressure margins.
  • Segment mix and one-time items may affect quarter-to-quarter comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

-1.6%

Avg return

Earnings day

-0.7%

Avg return

5 days after

+4.4%

Avg return

30 days after

47%

21 / 45 earnings

Positive

+36.4%

Q4 2018

Best reaction

-45.8%

Q3 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.8%-6.0%-5.8%
Q4 2025-25.1%-15.8%-20.0%
Q3 2025+21.8%+1.8%+8.2%
Q1 2025-4.6%-5.5%+21.2%
Q4 2024+19.7%+18.4%+5.0%
Q3 2024-5.9%+4.9%+2.0%
Q2 2024+6.7%+12.3%-30.4%
Q1 2024-1.8%-4.0%-22.2%
Q4 2023-10.8%-21.5%-19.7%
Q3 2023+4.9%+9.4%+41.5%
Q2 2023+5.8%+13.3%+2.5%
Q1 2023+19.8%+19.4%+35.0%
Q4 2022-20.1%-26.6%-23.1%
Q3 2022+25.5%+50.9%+106.0%
Q2 2022+23.5%+17.4%-17.0%
Q1 2022-19.1%-26.0%-4.9%
Q4 2021+13.5%+25.7%+34.2%
Q3 2021-39.1%-42.2%-54.6%
Q2 2021+3.6%+3.6%+7.9%
Q1 2021+1.6%-0.8%+17.0%
Q4 2020-11.9%-11.9%-12.6%
Q3 2020-11.0%+1.3%+31.8%
Q2 2020-5.7%-7.9%-11.6%
Q1 2020+11.2%+23.1%+6.4%
Q4 2019-2.4%-18.8%-43.9%
Q3 2019+4.2%+18.0%+9.1%
Q2 2019+26.7%+25.8%+22.1%
Q1 2019-38.6%-41.5%-53.9%
Q4 2018+36.4%+35.3%+35.9%
Q3 2018-45.8%-39.5%-37.3%
Q2 2018-7.5%-7.1%-2.1%
Q1 2018-19.0%-18.9%-24.3%
Q4 2017+8.7%+16.7%+4.1%
Q3 2017-22.2%-24.3%-23.9%
Q2 2017-11.6%-1.7%+28.0%
Q1 2017+1.5%+4.3%+163.9%
Q4 2016-10.6%-8.3%+1.4%
Q3 2016+21.3%-0.5%-9.4%
Q3 2015-9.6%
Q1 2015+2.0%
Q4 2014-3.3%
Q1 2013+3.7%
Q3 2012-6.4%
Q2 2012+0.0%
Q1 2012+1.9%
Q3 2011
Q2 2011
Q1 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

Discussion

Share your read of this quarter. Sign-in carries your eToro identity.

Join the conversation

Sign in with eToro to post your read of this quarter and vote on others'.

Sign in with eToro