NASDAQ$LYRA

Lyra Therapeutics Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

LYRA reported Q3 2025 a net loss of $22.0M.

For Q3 2025, LYRA reported net loss was $22.0M. The filing discusses operating performance, liquidity, and outlook in MD&A.

  • Net loss $22.0M.
  • MD&A covers R&D, cash runway, and sector-specific risks.
  • MD&A covers R&D, cash runway, and sector-specific risks.

Headline financials

Total Revenue

$25K

Previous: $195K-87.2%
EPS (adj)

-$3.38

Previous: -$0.18-1777.8%
Capital Expenditures

-$20K

Previous: -$2.4M+99.2%
Free Cash Flow

-$6M

Previous: -$14.3M+57.9%
Net Income

-$5.98M

Previous: -$11.9M+49.6%
Operating Income

-$6.24M

Previous: -$12.4M+49.9%
Gross Profit

$0.00

No prior period

Revenue & EPS history

Lyra · Revenue · Quarterly

$25K

Q3 2025-87.2%vs Q3 2024
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

Lyra · $410K total across 1 segment · Q1 2023

  • Collaboration revenue
    $410K

Forward guidance

Outlook focuses on cash runway, pipeline milestones, and cost discipline as the company works toward profitability.

Tailwinds

  • Cash and equivalents support operations into upcoming milestones.
  • Clinical or product pipeline progress noted in MD&A.

Headwinds

  • Ongoing operating losses and R&D spend pressure near-term earnings.
  • Financing, dilution, or partnership timing may affect liquidity.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

-1.6%

Avg return

Earnings day

-3.1%

Avg return

5 days after

-1.7%

Avg return

30 days after

29%

7 / 24 earnings

Positive

+11.0%

Q1 2024

Best reaction

-25.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+0.0%+0.1%+52.2%
Q3 2025-1.0%-5.9%-6.3%
Q2 2025+9.5%+8.3%-6.8%
Q1 2025-6.3%-17.3%+102.9%
Q4 2024-4.1%-14.8%-39.2%
Q3 2024-25.4%-35.8%-23.8%
Q2 2024-3.3%+4.0%-6.6%
Q1 2024+11.0%-14.8%-93.0%
Q4 2023+2.8%+1.0%-14.5%
Q3 2023+0.0%+2.4%+33.4%
Q2 2023+5.4%+13.8%+20.8%
Q1 2023-6.8%-2.1%+3.6%
Q4 2022+6.1%+13.8%+22.4%
Q3 2022-17.9%-20.3%-35.8%
Q2 2022-1.7%+0.6%-5.2%
Q1 2022+7.1%+7.7%+18.1%
Q4 2021-4.0%-5.8%+22.8%
Q3 2021-1.0%-0.4%-32.9%
Q2 2021-3.9%-0.4%+17.6%
Q1 2021-1.0%-5.6%+11.9%
Q4 2020-4.8%-2.2%-20.9%
Q3 2020+1.0%-1.8%-13.3%
Q2 2020-0.9%+0.9%-17.8%
Q1 2020-0.5%+0.1%-31.6%
Q3 2019
Q2 2019
Q1 2019

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