NASDAQ$LYRA

Lyra Therapeutics Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Reported financial results for the third quarter ended September 30, 2022 and provided a corporate update.

Lyra Therapeutics reported its Q3 2022 financial results, highlighting the advancement of their ENLIGHTEN I pivotal Phase 3 trial of LYR-210 in Chronic Rhinosinusitis (CRS) and the prioritization of in-house manufacturing capabilities. Enrollment in the ENLIGHTEN II trial is temporarily paused to align with manufacturing timelines, with resumption expected in Q3 2023. The company's cash and cash equivalents were reported as $109.6 million as of September 30, 2022, expected to fund operations through mid-2024.

  • ENLIGHTEN I pivotal Phase 3 trial of LYR-210 in CRS is on track, with full enrollment anticipated mid-2023.
  • BEACON Phase 2 trial of LYR-220 in post-surgical CRS patients has advanced to the randomized stage.
  • Lyra is prioritizing in-house manufacturing for clinical trial supply, leading to a temporary pause in ENLIGHTEN II enrollment, expected to resume in Q3 2023.
  • Cash and cash equivalents were $109.6 million as of September 30, 2022, expected to fund operations through mid-2024.

Headline financials

Total Revenue

$359K

Previous: $14K+2464.3%
EPS (adj)

-$0.40

Previous: -$0.85+52.9%
Capital Expenditures

-$136K

Previous: -$2.3M+94.1%
Free Cash Flow

-$14.9M

Previous: -$13.4M-11.6%
Net Income

-$14.8M

Previous: -$11.1M-33.6%
Operating Income

-$14.8M

Previous: -$11.1M-33.8%
Gross Profit

$359K

Previous: -$6.36M+105.6%
Cash & Equivalents

$110M

Previous: $58.1M+88.5%
Total Assets

$119M

Previous: $67.8M+76.3%
Stock-Based Comp

$1.74M

Previous: $733K+137.2%

Revenue & EPS history

Lyra · Revenue · Quarterly

$359K

Q3 2022+2,464.3%vs Q3 2021
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

Lyra · $410K total across 1 segment · Q1 2023

  • Collaboration revenue
    $410K

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

-1.6%

Avg return

Earnings day

-3.1%

Avg return

5 days after

-1.7%

Avg return

30 days after

29%

7 / 24 earnings

Positive

+11.0%

Q1 2024

Best reaction

-25.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+0.0%+0.1%+52.2%
Q3 2025-1.0%-5.9%-6.3%
Q2 2025+9.5%+8.3%-6.8%
Q1 2025-6.3%-17.3%+102.9%
Q4 2024-4.1%-14.8%-39.2%
Q3 2024-25.4%-35.8%-23.8%
Q2 2024-3.3%+4.0%-6.6%
Q1 2024+11.0%-14.8%-93.0%
Q4 2023+2.8%+1.0%-14.5%
Q3 2023+0.0%+2.4%+33.4%
Q2 2023+5.4%+13.8%+20.8%
Q1 2023-6.8%-2.1%+3.6%
Q4 2022+6.1%+13.8%+22.4%
Q3 2022-17.9%-20.3%-35.8%
Q2 2022-1.7%+0.6%-5.2%
Q1 2022+7.1%+7.7%+18.1%
Q4 2021-4.0%-5.8%+22.8%
Q3 2021-1.0%-0.4%-32.9%
Q2 2021-3.9%-0.4%+17.6%
Q1 2021-1.0%-5.6%+11.9%
Q4 2020-4.8%-2.2%-20.9%
Q3 2020+1.0%-1.8%-13.3%
Q2 2020-0.9%+0.9%-17.8%
Q1 2020-0.5%+0.1%-31.6%
Q3 2019
Q2 2019
Q1 2019

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