NASDAQ$LYRA

Lyra Therapeutics Inc · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Lyra Therapeutics reported Q1 2025 revenue of $183.0K, a net loss of $8.5M, diluted EPS of $-0.13.

For Q1 2025, Lyra Therapeutics reported Revenue was $183.0K, net loss was $8.5M, diluted EPS was $-0.13. Management discusses segment trends, liquidity, and outlook in the quarterly filing.

  • Revenue $183.0K for Q1 2025.
  • Net loss $8.5M.
  • Diluted EPS $-0.13.

Headline financials

Total Revenue

$183K

Previous: $532K-65.6%
EPS (adj)

-$0.13

Previous: -$0.35+62.9%
Net loss per share

-$0.13

Previous: -$0.35+62.9%
Weighted-average common shares outstanding

65.8M

Previous: 64.0M+2.7%
R&D expenses

$4.88M

Previous: $18.2M-73.3%
G&A expenses

$3.26M

Previous: $5.82M-43.9%
Restructuring and other related charges

$885K

No prior period
Total operating expenses

$9.02M

Previous: $24.1M-62.5%
Interest income

$298K

Previous: $1.09M-72.6%
Income tax expense

$4K

Previous: $14K-71.4%
Unrealized holding gain (loss) on short-term investments, net of tax

$0.00

Previous: -$8K+100.0%
Comprehensive loss

-$8.55M

Previous: -$22.5M+61.9%
Capital Expenditures

-$2.15M

Previous: -$2.15M+0.0%
Net Income

-$8.55M

Previous: -$22.5M+61.9%
Operating Income

-$8.84M

Previous: -$23.5M+62.4%

Revenue & EPS history

Lyra · Revenue · Quarterly

$183K

Q1 2025-65.6%vs Q1 2024
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

Lyra · $410K total across 1 segment · Q1 2023

  • Collaboration revenue
    $410K

Forward guidance

Outlook emphasizes clinical milestones, liquidity runway, and cost discipline.

Tailwinds

  • Pipeline readouts and partnership economics.
  • Cash balance supports near-term development plans.

Headwinds

  • Operating losses and trial risk until commercialization.
  • Financing markets and competition affect funding costs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-1.6%

Avg return

Earnings day

-3.1%

Avg return

5 days after

-1.7%

Avg return

30 days after

29%

7 / 24 earnings

Positive

+11.0%

Q1 2024

Best reaction

-25.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+0.0%+0.1%+52.2%
Q3 2025-1.0%-5.9%-6.3%
Q2 2025+9.5%+8.3%-6.8%
Q1 2025-6.3%-17.3%+102.9%
Q4 2024-4.1%-14.8%-39.2%
Q3 2024-25.4%-35.8%-23.8%
Q2 2024-3.3%+4.0%-6.6%
Q1 2024+11.0%-14.8%-93.0%
Q4 2023+2.8%+1.0%-14.5%
Q3 2023+0.0%+2.4%+33.4%
Q2 2023+5.4%+13.8%+20.8%
Q1 2023-6.8%-2.1%+3.6%
Q4 2022+6.1%+13.8%+22.4%
Q3 2022-17.9%-20.3%-35.8%
Q2 2022-1.7%+0.6%-5.2%
Q1 2022+7.1%+7.7%+18.1%
Q4 2021-4.0%-5.8%+22.8%
Q3 2021-1.0%-0.4%-32.9%
Q2 2021-3.9%-0.4%+17.6%
Q1 2021-1.0%-5.6%+11.9%
Q4 2020-4.8%-2.2%-20.9%
Q3 2020+1.0%-1.8%-13.3%
Q2 2020-0.9%+0.9%-17.8%
Q1 2020-0.5%+0.1%-31.6%
Q3 2019
Q2 2019
Q1 2019

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