NASDAQ$LYRA

Lyra Therapeutics Inc · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Lyra Therapeutics reported its financial results for the third quarter ended September 30, 2024 and provided a corporate update.

Lyra Therapeutics reported its Q3 2024 financial results, highlighting the anticipation of key milestones from the ongoing ENLIGHTEN Phase 3 trials and the topline safety data from the ENLIGHTEN 1 safety extension study. The company's cash, cash equivalents, and short-term investments were $51.6 million as of September 30, 2024, expected to fund operations into the first quarter of 2026.

  • Topline safety results from ENLIGHTEN 1 Phase 3 extension study indicated no product-related serious adverse events.
  • Enrollment in ENLIGHTEN 2 completed.
  • Topline results from ENLIGHTEN 2 are expected in Q2 2025.
  • Cash, cash equivalents and short-term investments as of September 30, 2024 were $51.6 million.

Headline financials

Total Revenue

$195K

Previous: $544K-64.2%
EPS

-$0.18

Previous: -$0.27+33.3%
Capital Expenditures

-$2.4M

Previous: -$260K-821.5%
Free Cash Flow

-$14.3M

Previous: -$15.9M+10.3%
Net Income

-$11.9M

Previous: -$15.7M+24.1%
Operating Income

-$12.4M

Previous: -$16.8M+26.1%
R&D Expense

$5.9M

Previous: $12.4M-52.3%
Stock-Based Comp

$1.49M

Previous: $1.44M+3.5%

Revenue & EPS history

Lyra · Revenue · Quarterly

$195K

Q3 2024-64.2%vs Q3 2023
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

Lyra · $410K total across 1 segment · Q1 2023

  • Collaboration revenue
    $410K

Forward guidance

Lyra Therapeutics anticipates key milestones from the two ongoing ENLIGHTEN Phase 3 trials, which will provide a more complete data set and greater insight into determining a potential pathway to approval for LYR-210 in CRS patients. Based on our current business plan, we anticipate that our cash, cash equivalents and short-term investment balance is sufficient to fund our operating expenses and capital expenditures into the first quarter of 2026.

Tailwinds

  • Topline results from ENLIGHTEN 2 are expected in Q2 2025.
  • Safety data for LYR-210 was generally consistent with the 24-week primary treatment phase.
  • LYR-210 was generally well tolerated, with no product-related serious adverse events.
  • Enrollment in ENLIGHTEN 2 completed.
  • Cash, cash equivalents and short-term investments as of September 30, 2024 were $51.6 million.

Headwinds

  • The ENLIGHTEN 1 trial did not meet its primary endpoint, which led to scaling back activities.
  • Decrease in research and development expenses.
  • Decrease in general and administrative expenses.
  • Net loss for the quarter ended September 30, 2024 was $11.9 million.
  • Company is still awaiting data readouts to guide data-driven evaluations as they determine potential path for LYR-210.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

-1.6%

Avg return

Earnings day

-3.1%

Avg return

5 days after

-1.7%

Avg return

30 days after

29%

7 / 24 earnings

Positive

+11.0%

Q1 2024

Best reaction

-25.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+0.0%+0.1%+52.2%
Q3 2025-1.0%-5.9%-6.3%
Q2 2025+9.5%+8.3%-6.8%
Q1 2025-6.3%-17.3%+102.9%
Q4 2024-4.1%-14.8%-39.2%
Q3 2024-25.4%-35.8%-23.8%
Q2 2024-3.3%+4.0%-6.6%
Q1 2024+11.0%-14.8%-93.0%
Q4 2023+2.8%+1.0%-14.5%
Q3 2023+0.0%+2.4%+33.4%
Q2 2023+5.4%+13.8%+20.8%
Q1 2023-6.8%-2.1%+3.6%
Q4 2022+6.1%+13.8%+22.4%
Q3 2022-17.9%-20.3%-35.8%
Q2 2022-1.7%+0.6%-5.2%
Q1 2022+7.1%+7.7%+18.1%
Q4 2021-4.0%-5.8%+22.8%
Q3 2021-1.0%-0.4%-32.9%
Q2 2021-3.9%-0.4%+17.6%
Q1 2021-1.0%-5.6%+11.9%
Q4 2020-4.8%-2.2%-20.9%
Q3 2020+1.0%-1.8%-13.3%
Q2 2020-0.9%+0.9%-17.8%
Q1 2020-0.5%+0.1%-31.6%
Q3 2019
Q2 2019
Q1 2019

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