NASDAQ$AXSM

Axsome Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

Axsome Therapeutics reported Q2 2025 revenue of $150.0 million with continued commercial progress for Auvelity, Sunosi, and Symbravo.

Total revenues reached $150.0 million in the quarter, driven primarily by product sales of $149.0 million. The company recorded a net loss of $48.0 million or $0.97 per share. Cash and cash equivalents stood at $303.0 million at quarter end with total assets of $639.8 million.

  • Q2 2025 total revenues of $150.0 million reflected strong growth in Auvelity and Sunosi sales plus initial Symbravo contribution.
  • Net loss narrowed to $48.0 million compared with $79.3 million in the prior-year quarter.
  • R&D expenses were $49.5 million and SG&A expenses were $130.3 million as commercial infrastructure expanded.
  • Cash position remained solid at $303.0 million supporting ongoing operations and pipeline advancement.

Headline financials

Total Revenue

$150M

Previous: $87.2M+72.1%
EPS (adj)

-$0.97

Previous: -$1.67+41.9%
R&D Expenses

$49.5M

Previous: $49.9M-0.6%
SG&A Expenses

$130M

Previous: $104M+25.8%
Total Shares Outstanding

49.8M

No prior period
Capital Expenditures

-$351K

Previous: -$150K-134.0%
Net Income

-$48M

Previous: -$79.3M+39.5%
Operating Income

-$36.7M

Previous: -$78M+53.0%
Cash & Equivalents

$303M

Previous: $316M-4.0%
Total Assets

$640M

Previous: $548M+16.7%

Revenue & EPS history

Axsome · Revenue · Quarterly

$150M

Q2 2025+72.1%vs Q2 2024
Beat estimate in 9 of 16 quarters(56%)
ActualEstimate

Revenue by segment

Axsome · $149M total across 3 segments · Q2 2025

  • Auvelity
    $120M
  • Sunosi
    $28.9M
  • Symbravo
    $410K

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports

Historical avg

-1.0%

Avg return

Earnings day

-2.9%

Avg return

5 days after

+1.7%

Avg return

30 days after

51%

21 / 41 earnings

Positive

+12.9%

Q1 2022

Best reaction

-53.5%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026+8.1%+5.3%+13.0%
Q4 2025-4.7%-10.8%-11.9%
Q3 2025+1.9%+2.3%+9.5%
Q1 2025+3.7%-4.0%-3.6%
Q4 2024-2.3%+5.0%-3.7%
Q3 2024+7.5%+2.4%+3.7%
Q2 2024+1.3%-1.6%+13.2%
Q1 2024+2.9%-3.1%-0.9%
Q4 2023-11.5%-14.9%-12.9%
Q3 2023-3.1%-11.9%+6.5%
Q2 2023-1.5%-5.5%+10.7%
Q1 2023+4.1%+7.1%+2.4%
Q4 2022+11.7%+6.9%+2.3%
Q3 2022+11.2%+3.4%+36.9%
Q2 2022+11.7%+6.8%+41.3%
Q1 2022+12.9%-6.1%-24.3%
Q4 2021+11.9%+6.4%+47.2%
Q3 2021+1.4%-2.3%-12.6%
Q2 2021-53.5%-55.3%-48.9%
Q1 2021+0.1%+2.6%+11.5%
Q4 2020+3.6%-3.5%-15.9%
Q3 2020-9.7%-6.3%+7.1%
Q2 2020-0.6%+1.2%-7.3%
Q1 2020-2.8%-7.9%-15.7%
Q4 2019-16.8%-38.7%-23.8%
Q3 2019-1.2%-4.6%+76.4%
Q2 2019+2.2%+11.0%-0.5%
Q1 2019+7.2%+10.7%+12.2%
Q4 2018+4.6%+24.3%+29.2%
Q3 2018-15.8%-28.1%-24.7%
Q2 2018-1.9%-8.6%+27.6%
Q1 2018+1.5%+3.0%+4.5%
Q4 2017+2.6%+6.5%-8.4%
Q3 2017-4.1%+1.0%-0.5%
Q2 2017-5.0%-12.6%-19.3%
Q1 2017-1.2%-1.2%-4.8%
Q4 2016-4.1%+6.1%-27.6%
Q3 2016+0.7%+4.1%-17.8%
Q2 2016-1.4%-3.4%-1.6%
Q1 2016-1.4%-3.4%-1.6%
Q4 2015-10.0%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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