NASDAQ$AXSM

Axsome Therapeutics Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Axsome Therapeutics reported Q1 2025, revenue of $75M, net loss of $59.4M, diluted EPS of $-1.22.

For Q1 2025, Axsome Therapeutics reported revenue of $75M, a net loss of $59.4M, diluted EPS was $-1.22. Management discusses operating trends, capital, and sector risks in the quarterly filing.

  • Q1 2025 revenue $75M.
  • Net loss $59.4M.
  • Diluted EPS $-1.22.

Headline financials

Total Revenue

$121M

Previous: $75M+62.0%
EPS (adj)

-$1.22

Previous: -$1.44+15.3%
Capital Expenditures

-$338K

Previous: -$98K-244.9%
Free Cash Flow

-$43.7M

Previous: -$68.5M+36.1%
Net Income

-$59.4M

Previous: -$68.4M+13.1%
Operating Income

-$57M

Previous: -$67.3M+15.3%
Gross Profit

$110M

Previous: -$6.3M+1839.6%
R&D Expense

$44.2M

Previous: $36.6M+20.9%

Revenue & EPS history

Axsome · Revenue · Quarterly

$121M

Q1 2025+62%vs Q1 2024
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Axsome · $57.8M total across 2 segments · Q3 2023

  • AUVELITY
    $37.7M
  • SUNOSI
    $20.1M+19.6%

Forward guidance

Growth and biotech filers emphasize pipeline, commercial ramp, and cash runway rather than near-term GAAP profitability targets.

Tailwinds

  • Product revenue growth or launch momentum.
  • Partnership and platform expansion.
  • Balance sheet liquidity for R&D.

Headwinds

  • Operating losses until scale is reached.
  • R&D and SG&A spend ahead of revenue.
  • Regulatory and reimbursement risk.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-1.0%

Avg return

Earnings day

-2.9%

Avg return

5 days after

+1.7%

Avg return

30 days after

51%

21 / 41 earnings

Positive

+12.9%

Q1 2022

Best reaction

-53.5%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.1%+5.3%+13.0%
Q4 2025-4.7%-10.8%-11.9%
Q3 2025+1.9%+2.3%+9.5%
Q1 2025+3.7%-4.0%-3.6%
Q4 2024-2.3%+5.0%-3.7%
Q3 2024+7.5%+2.4%+3.7%
Q2 2024+1.3%-1.6%+13.2%
Q1 2024+2.9%-3.1%-0.9%
Q4 2023-11.5%-14.9%-12.9%
Q3 2023-3.1%-11.9%+6.5%
Q2 2023-1.5%-5.5%+10.7%
Q1 2023+4.1%+7.1%+2.4%
Q4 2022+11.7%+6.9%+2.3%
Q3 2022+11.2%+3.4%+36.9%
Q2 2022+11.7%+6.8%+41.3%
Q1 2022+12.9%-6.1%-24.3%
Q4 2021+11.9%+6.4%+47.2%
Q3 2021+1.4%-2.3%-12.6%
Q2 2021-53.5%-55.3%-48.9%
Q1 2021+0.1%+2.6%+11.5%
Q4 2020+3.6%-3.5%-15.9%
Q3 2020-9.7%-6.3%+7.1%
Q2 2020-0.6%+1.2%-7.3%
Q1 2020-2.8%-7.9%-15.7%
Q4 2019-16.8%-38.7%-23.8%
Q3 2019-1.2%-4.6%+76.4%
Q2 2019+2.2%+11.0%-0.5%
Q1 2019+7.2%+10.7%+12.2%
Q4 2018+4.6%+24.3%+29.2%
Q3 2018-15.8%-28.1%-24.7%
Q2 2018-1.9%-8.6%+27.6%
Q1 2018+1.5%+3.0%+4.5%
Q4 2017+2.6%+6.5%-8.4%
Q3 2017-4.1%+1.0%-0.5%
Q2 2017-5.0%-12.6%-19.3%
Q1 2017-1.2%-1.2%-4.8%
Q4 2016-4.1%+6.1%-27.6%
Q3 2016+0.7%+4.1%-17.8%
Q2 2016-1.4%-3.4%-1.6%
Q1 2016-1.4%-3.4%-1.6%
Q4 2015-10.0%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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