NASDAQ$AXSM

Axsome Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Axsome reported its financial results for Q1 2022 and provided a business update.

Axsome Therapeutics reported a net loss of $39.6 million, or $(1.03) per share, for the first quarter ended March 31, 2022. The company's R&D expenses were $12.6 million, while G&A expenses were $25.7 million. Axsome had $84.7 million in cash as of March 31, 2022 and anticipates potential FDA action on the NDA in the second quarter of 2022.

  • NDA for AXS-05 in depression is under review with potential FDA action expected in Q2 2022.
  • Acquisition of Sunosi is expected to close in Q2 2022 for the U.S. transaction.
  • NDA resubmission for AXS-07 in migraine is planned following engagement with the FDA.
  • Topline results from Phase 3 trials of AXS-12 in narcolepsy and AXS-05 in Alzheimer’s disease agitation are anticipated in 2023.

Headline financials

EPS (adj)

-$1.03

Previous: -$0.78-32.1%
R&D Expenses

$12.6M

Previous: $16.6M-24.2%
SG&A Expenses

$25.7M

Previous: $11.2M+128.5%
Total Shares Outstanding

38.9M

No prior period
Capital Expenditures

$214K

No prior period
Free Cash Flow

-$32.9M

No prior period
Net Income

-$39.6M

Previous: -$29.3M-35.4%
Operating Income

-$38.3M

No prior period
Cash & Equivalents

$84.7M

Previous: $165M-48.6%
Total Assets

$88.6M

Previous: $167M-46.9%
Stock-Based Comp

$7.6M

No prior period

Revenue & EPS history

Axsome · Revenue · Quarterly

$191M

Q1 2026+57.4%vs Q1 2025
Beat estimate in 4 of 9 quarters(44%)
ActualEstimate

Revenue by segment

Axsome · $57.8M total across 2 segments · Q3 2023

  • AUVELITY
    $37.7M
  • SUNOSI
    $20.1M+19.6%

Forward guidance

Axsome believes its current cash, along with the remaining committed capital from the $300 million term loan facility, is sufficient to fund anticipated operations into 2024. The company expects that its operating expenses will increase year over year as it continues to build out the commercial function and further advance its pipeline.

Tailwinds

  • Current cash is sufficient to fund operations into 2024.
  • Remaining committed capital from the $300 million term loan facility will support operations.
  • Potential launch of AXS-05 in MDD is included in the operating plan.
  • Acquisition and commercialization of Sunosi is included in the operating plan.
  • Sunosi acquisition U.S. and ex-U.S. transaction closings (2Q, 3Q 2022, respectively)

Headwinds

  • Operating expenses will increase year over year.
  • Building out the commercial function will increase expenses.
  • Further advancing the pipeline will increase expenses.
  • Received a Complete Response Letter (CRL) from the FDA regarding its NDA for AXS-07
  • Net loss of $39.6 million for the three months ended March 31, 2022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-1.0%

Avg return

Earnings day

-2.9%

Avg return

5 days after

+1.7%

Avg return

30 days after

51%

21 / 41 earnings

Positive

+12.9%

Q1 2022

Best reaction

-53.5%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.1%+5.3%+13.0%
Q4 2025-4.7%-10.8%-11.9%
Q3 2025+1.9%+2.3%+9.5%
Q1 2025+3.7%-4.0%-3.6%
Q4 2024-2.3%+5.0%-3.7%
Q3 2024+7.5%+2.4%+3.7%
Q2 2024+1.3%-1.6%+13.2%
Q1 2024+2.9%-3.1%-0.9%
Q4 2023-11.5%-14.9%-12.9%
Q3 2023-3.1%-11.9%+6.5%
Q2 2023-1.5%-5.5%+10.7%
Q1 2023+4.1%+7.1%+2.4%
Q4 2022+11.7%+6.9%+2.3%
Q3 2022+11.2%+3.4%+36.9%
Q2 2022+11.7%+6.8%+41.3%
Q1 2022+12.9%-6.1%-24.3%
Q4 2021+11.9%+6.4%+47.2%
Q3 2021+1.4%-2.3%-12.6%
Q2 2021-53.5%-55.3%-48.9%
Q1 2021+0.1%+2.6%+11.5%
Q4 2020+3.6%-3.5%-15.9%
Q3 2020-9.7%-6.3%+7.1%
Q2 2020-0.6%+1.2%-7.3%
Q1 2020-2.8%-7.9%-15.7%
Q4 2019-16.8%-38.7%-23.8%
Q3 2019-1.2%-4.6%+76.4%
Q2 2019+2.2%+11.0%-0.5%
Q1 2019+7.2%+10.7%+12.2%
Q4 2018+4.6%+24.3%+29.2%
Q3 2018-15.8%-28.1%-24.7%
Q2 2018-1.9%-8.6%+27.6%
Q1 2018+1.5%+3.0%+4.5%
Q4 2017+2.6%+6.5%-8.4%
Q3 2017-4.1%+1.0%-0.5%
Q2 2017-5.0%-12.6%-19.3%
Q1 2017-1.2%-1.2%-4.8%
Q4 2016-4.1%+6.1%-27.6%
Q3 2016+0.7%+4.1%-17.8%
Q2 2016-1.4%-3.4%-1.6%
Q1 2016-1.4%-3.4%-1.6%
Q4 2015-10.0%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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