NASDAQ$AMLX

Amylyx Pharmaceuticals Inc · Q3 2023 earnings

Q3 2023 earnings · · Investor relations

Briefing

Reported strong Q3 2023 financial results with significant product revenue and net income.

Amylyx Pharmaceuticals reported a successful third quarter in 2023, marked by $102.7 million in product revenue and a net income of $20.9 million. The company's financial position remains strong, supported by cash, cash equivalents, and short-term investments totaling $355.0 million.

  • Third quarter product revenue reached $102.7 million, contributing to $272.3 million in the first three full quarters of U.S. launch.
  • Net income for the third quarter stood at $20.9 million.
  • Cash, cash equivalents, and short-term investments totaled $355.0 million as of September 30, 2023.
  • Continued progress of commercial launches of RELYVRIO® in the U.S. and ALBRIOZA™ in Canada

Headline financials

Total Revenue

$103M

Previous: $345K+29666.1%
EPS (adj)

$0.30

Previous: -$0.92+132.6%
Capital Expenditures

-$885K

Previous: -$1.91M+53.6%
Free Cash Flow

$20M

Previous: -$55.7M+135.9%
Net Income

$20.9M

Previous: -$53.8M+138.9%
Operating Income

$18.7M

Previous: -$54.7M+134.2%
Gross Profit

$97.5M

Previous: $173K+56243.9%
Cash & Equivalents

$355M

Previous: $108M+229.5%
Total Assets

$467M

Previous: $181M+157.2%
R&D Expense

$29.7M

No prior period
Stock-Based Comp

$10.2M

Previous: $5.52M+84.2%

Revenue & EPS history

Amylyx · Revenue · Quarterly

$103M

Q3 2023+29,666.1%vs Q3 2022
Beat estimate in 3 of 8 quarters(38%)
ActualEstimate

Forward guidance

Amylyx anticipates topline data from the Phase 3 PHOENIX trial in the second quarter of 2024 and is working on a new taste-masked formulation of RELYVRIO for Phase 1 testing in 2024.

Tailwinds

  • Company plans to seek approval in the EU as quickly as possible if PHOENIX is supportive.
  • The Company continues to expect data from the Phase 2 clinical trial of AMX0035 in Wolfram syndrome in 2024.
  • The Company is planning to file an IND and conduct Phase 1 testing for this innovative formulation in 2024.
  • The goal of this program is to create a tool that allows for earlier diagnosis of ALS which may result in earlier treatment and better outcomes.
  • ORION study initiation anticipated by the end of 2023 starting in the United States.

Headwinds

  • The CHMP opinion will be forwarded to the European Commission, who will adopt the final decision on this application anticipated by the end of 2023.
  • The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) confirmed its initial negative opinion adopted in June 2023 on the Marketing Authorisation Application (MAA) for AMX0035 for the treatment of ALS in the European Union (EU).
  • Risk in Patients with Enterohepatic Circulation Disorders, Pancreatic Disorders, or Intestinal Disorders
  • Use in Patients Sensitive to High Sodium Intake
  • RELYVRIO has a high salt content.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q3 2023

Historical avgQ3 2023

+0.3%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+7.4%

Avg return

30 days after

44%

8 / 18 earnings

Positive

+23.4%

Q4 2021

Best reaction

-30.7%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-7.6%-9.5%-2.3%
Q3 2025-5.9%-4.2%+7.3%
Q1 2025-6.0%-7.8%+9.4%
Q4 2024+0.3%+29.0%+17.0%
Q3 2024+7.7%+0.3%-17.4%
Q2 2024+1.1%+5.9%+26.1%
Q1 2024-8.8%-3.1%-8.3%
Q4 2023+15.3%+24.1%-82.1%
Q3 2023-30.7%-30.4%-22.2%
Q2 2023+0.5%-2.3%-4.5%
Q1 2023-4.4%-6.1%-11.9%
Q4 2022+11.2%-1.2%-3.9%
Q3 2022-1.8%+2.4%+3.0%
Q3 2021-1.8%+2.4%+3.0%
Q2 2021-5.5%-5.7%+12.7%
Q2 2022-5.5%-5.7%+12.7%
Q4 2021+23.4%+28.2%+97.5%
Q1 2022+23.4%+28.2%+97.5%
Q1 2021
Q4 2020

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