NASDAQ$AMLX
Amylyx Pharmaceuticals Inc · Q2 2025 earnings
Q2 2025 earnings · · Before market open · Investor relations
Briefing
Amylyx Pharmaceuticals Inc reported a net loss of $41.4 million for Q2 2025 with no product revenue.
The company recorded zero product revenue in the quarter following the discontinuation of RELYVRIO/ALBRIOZA. Operating expenses were $42.9 million, led by R&D investments of $27.2 million. Cash and cash equivalents stood at $58.1 million with total assets of $194.6 million at quarter end.
- Net loss of $41.4 million and diluted EPS of $(0.46) for the three months ended June 30, 2025.
- Research and development expenses totaled $27.2 million, including $2.0 million in stock-based compensation.
- Selling, general and administrative expenses were $15.6 million, including $5.4 million in stock-based compensation.
- Cash position of $58.1 million supports ongoing clinical development of avexitide and AMX0035.
Headline financials
Revenue & EPS history
Amylyx · Revenue · Quarterly
$0
Forward guidance
Company advancing Phase 3 LUCIDITY trial for avexitide in PBH and Phase 2/3 programs for AMX0035.
Tailwinds
- Positive long-term HELIOS data for AMX0035 in Wolfram syndrome through Week 48.
- First participant dosed in Phase 1 LUMINA trial for AMX0114 in ALS.
Headwinds
- No product revenue expected in near term.
- Continued operating losses anticipated during clinical development.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 18 quarterly earnings reports
+0.3%
Avg return
Earnings day
+2.5%
Avg return
5 days after
+7.4%
Avg return
30 days after
44%
8 / 18 earnings
Positive
+23.4%
Q4 2021
Best reaction
-30.7%
Q3 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q2 2025 | — | — | — | |
| Q4 2025 | -7.6% | -9.5% | -2.3% | |
| Q3 2025 | -5.9% | -4.2% | +7.3% | |
| Q1 2025 | -6.0% | -7.8% | +9.4% | |
| Q4 2024 | +0.3% | +29.0% | +17.0% | |
| Q3 2024 | +7.7% | +0.3% | -17.4% | |
| Q2 2024 | +1.1% | +5.9% | +26.1% | |
| Q1 2024 | -8.8% | -3.1% | -8.3% | |
| Q4 2023 | +15.3% | +24.1% | -82.1% | |
| Q3 2023 | -30.7% | -30.4% | -22.2% | |
| Q2 2023 | +0.5% | -2.3% | -4.5% | |
| Q1 2023 | -4.4% | -6.1% | -11.9% | |
| Q4 2022 | +11.2% | -1.2% | -3.9% | |
| Q3 2021 | -1.8% | +2.4% | +3.0% | |
| Q3 2022 | -1.8% | +2.4% | +3.0% | |
| Q2 2021 | -5.5% | -5.7% | +12.7% | |
| Q2 2022 | -5.5% | -5.7% | +12.7% | |
| Q4 2021 | +23.4% | +28.2% | +97.5% | |
| Q1 2022 | +23.4% | +28.2% | +97.5% | |
| Q1 2021 | — | — | — | |
| Q4 2020 | — | — | — |
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