NASDAQ$ADVM

Adverum Biotechnologies Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

Adverum Biotechnologies reported Q4 2024 with no license revenue and a net loss of $40.9M.

License revenue was nil for the quarter ended December 31, 2024, as the clinical-stage gene therapy company advanced Ixo-vec and pipeline programs. Net loss was $40.9 million ($1.96 diluted loss per share) on elevated R&D. Cash runway and trial milestones dominate outlook.

  • Pre-commercial; no license revenue in Q4.
  • Net loss $40.9M; diluted LPS $1.96.
  • R&D spending increased on ophthalmology programs.
  • Trial readouts and financing needs drive the outlook.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$1.96

Previous: -$2.30+14.8%
R&D expenses

$24.1M

Previous: $15.3M+57.7%
Stock comp in R&D

$1.2M

No prior period
G&A expenses

$18.5M

Previous: $11.7M+58.7%
Stock comp in G&A

$2M

No prior period
Capital Expenditures

-$61K

Previous: -$192K+68.2%
Net Income

-$40.9M

Previous: -$23.7M-72.6%
Operating Income

-$42.6M

Previous: -$26.2M-62.9%
Gross Profit

-$810K

Previous: -$1.01M+19.7%
R&D Expense

$24.1M

Previous: $15.1M+59.8%

Revenue & EPS history

Adverum · Revenue · Quarterly

$0

Q4 2024
Beat estimate in 1 of 4 quarters(25%)
ActualEstimate

Forward guidance

Outlook emphasizes clinical milestones, liquidity, and path to profitability.

Tailwinds

  • Cash and strategic partnerships can fund pipeline advancement.
  • Cost discipline may narrow operating losses.

Headwinds

  • No product revenue until regulatory approval for pre-commercial names.
  • Trial outcomes and dilution risk affect funding needs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-2.5%

Avg return

30 days after

45%

17 / 38 earnings

Positive

+12.5%

Q3 2022

Best reaction

-15.5%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-0.9%-1.2%
Q2 2025+10.8%+27.9%+41.4%
Q1 2025-1.0%+21.0%+19.5%
Q4 2024-5.8%-15.4%-41.0%
Q3 2024+4.2%+8.4%-18.5%
Q2 2024+3.0%+4.7%+7.3%
Q1 2024-5.2%-9.3%-25.1%
Q4 2023-2.9%-5.3%-33.1%
Q3 2023+1.8%-3.4%+0.0%
Q2 2023+2.2%-3.8%-7.1%
Q1 2023-4.6%-4.1%+89.3%
Q4 2022-4.5%-6.7%+3.6%
Q3 2022+12.5%+3.2%-9.6%
Q2 2022-4.5%-8.6%-25.0%
Q1 2022-14.1%-13.5%+2.7%
Q4 2021-2.9%-5.8%-20.3%
Q3 2021-5.6%-1.3%-24.9%
Q2 2021+6.9%
Q1 2021+3.3%
Q4 2020-5.3%
Q3 2020-7.8%
Q2 2020-15.5%
Q1 2020-1.9%
Q4 2019+11.6%
Q3 2019+8.9%
Q2 2019-1.3%
Q1 2019-3.7%
Q4 2018+2.8%
Q3 2018+1.9%
Q2 2018+10.9%
Q1 2018+3.6%
Q4 2017-4.1%
Q3 2017-6.3%
Q2 2017-2.0%
Q1 2017-1.8%
Q3 2016+11.9%
Q2 2016+2.3%
Q3 2014+4.5%
Q2 2014
Q1 2014
Q4 2014
Q3 2013
Q2 2013
Q1 2013

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