NASDAQ$ADVM

Adverum Biotechnologies Inc · Q4 2020 earnings

Q4 2020 earnings · · Investor relations

Briefing

Adverum gained alignment with the FDA on the clinical development path for ADVM-022 and reported financial results.

Adverum Biotechnologies announced alignment with the FDA on the clinical development path for ADVM-022 and reported its Q4 2020 financial results. The company is planning to initiate two global Phase 3 trials in Q4 2021 and anticipates a BLA submission in 2024.

  • Gained alignment with the FDA on the clinical development path for ADVM-022.
  • Planning to initiate two global Phase 3 trials in Q4 2021.
  • Anticipates BLA submission in 2024.
  • Expanding CMC capabilities and investing in an in-house GMP manufacturing facility.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$3.90

Previous: -$2.90-34.5%
Capital Expenditures

$1.43M

No prior period
Free Cash Flow

-$23.7M

No prior period
Net Income

-$37.6M

No prior period
Operating Income

-$36.4M

No prior period
Cash & Equivalents

$430M

No prior period
Total Assets

$483M

No prior period
Stock-Based Comp

$6.18M

No prior period

Revenue & EPS history

Adverum · Revenue · Quarterly

$0

Q4 2020
Beat estimate in 5 of 14 quarters(36%)
ActualEstimate

Forward guidance

Adverum is focused on advancing ADVM-022 and expanding its manufacturing capabilities.

Tailwinds

  • Initiate two global Phase 3 pivotal trials for ADVM-022 in wet AMD in the fourth quarter of 2021
  • Present long-term OPTIC data, including one-year data from Cohort 3 (2 x 10^11), in the second quarter of 2021
  • Present clinical data from INFINITY Phase 2 trial in the second half of 2021
  • Begin build-out of new GMP commercial manufacturing facility in North Carolina with multiple production suites, expected to be production-ready by the end of 2023 in preparation for commercialization of ADVM-022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports

Historical avg

+0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-2.5%

Avg return

30 days after

45%

17 / 38 earnings

Positive

+12.5%

Q3 2022

Best reaction

-15.5%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-0.9%-1.2%
Q2 2025+10.8%+27.9%+41.4%
Q1 2025-1.0%+21.0%+19.5%
Q4 2024-5.8%-15.4%-41.0%
Q3 2024+4.2%+8.4%-18.5%
Q2 2024+3.0%+4.7%+7.3%
Q1 2024-5.2%-9.3%-25.1%
Q4 2023-2.9%-5.3%-33.1%
Q3 2023+1.8%-3.4%+0.0%
Q2 2023+2.2%-3.8%-7.1%
Q1 2023-4.6%-4.1%+89.3%
Q4 2022-4.5%-6.7%+3.6%
Q3 2022+12.5%+3.2%-9.6%
Q2 2022-4.5%-8.6%-25.0%
Q1 2022-14.1%-13.5%+2.7%
Q4 2021-2.9%-5.8%-20.3%
Q3 2021-5.6%-1.3%-24.9%
Q2 2021+6.9%
Q1 2021+3.3%
Q4 2020-5.3%
Q3 2020-7.8%
Q2 2020-15.5%
Q1 2020-1.9%
Q4 2019+11.6%
Q3 2019+8.9%
Q2 2019-1.3%
Q1 2019-3.7%
Q4 2018+2.8%
Q3 2018+1.9%
Q2 2018+10.9%
Q1 2018+3.6%
Q4 2017-4.1%
Q3 2017-6.3%
Q2 2017-2.0%
Q1 2017-1.8%
Q3 2016+11.9%
Q2 2016+2.3%
Q3 2014+4.5%
Q2 2014
Q1 2014
Q4 2014
Q3 2013
Q2 2013
Q1 2013

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