NASDAQ$ADVM

Adverum Biotechnologies Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Reported financial results for the first quarter ended March 31, 2023 and provided an update on its ongoing Phase 2 LUNA trial.

Adverum Biotechnologies reported its first quarter 2023 financial results. The company's cash, cash equivalents and short-term investments were $164.3 million as of March 31, 2023, and expects this to fund operations into 2025. The company anticipates full enrollment of the Phase 2 LUNA trial in the second half of 2023.

  • Cash, cash equivalents and short-term investments were $164.3 million as of March 31, 2023.
  • Adverum expects the March 31, 2023 cash position to fund operations into 2025.
  • Enrollment in the Phase 2 LUNA trial evaluating Ixo-vec in subjects with wet AMD is expected to be completed during the second half of 2023.
  • The United Kingdom’s Medicines and Healthcare Products Regulatory Agency granted Ixo-vec an Innovation Passport under the Innovative Licensing and Access Pathway (ILAP.)

Headline financials

Total Revenue

$3.6M

Previous: $0.00
EPS (adj)

-$2.90

Previous: -$3.80+23.7%
Capital Expenditures

-$85K

Previous: -$4.37M+98.1%
Free Cash Flow

-$22.5M

Previous: -$33.3M+32.4%
Net Income

-$29.1M

Previous: -$37.9M+23.4%
Operating Income

-$30.2M

Previous: -$38.1M+20.7%
Gross Profit

$1.4M

No prior period
Cash & Equivalents

$164M

Previous: $271M-39.4%
Total Assets

$276M

Previous: $407M-32.4%
Stock-Based Comp

$4.56M

Previous: $5.38M-15.2%

Revenue & EPS history

Adverum · Revenue · Quarterly

$3.6M

Q1 2023
Beat estimate in 1 of 4 quarters(25%)
ActualEstimate

Forward guidance

Adverum anticipates full enrollment of the Phase 2 LUNA trial in the second half of 2023 and expects to provide interim datasets for a percentage of participants at 14 weeks, including aflibercept protein levels, in the third quarter of 2023, as well as preliminary efficacy and safety data in the fourth quarter of 2023.

Tailwinds

  • Full enrollment of the Phase 2 LUNA trial in wet age-related macular degeneration (wet AMD) is anticipated in the second half of 2023
  • LUNA 14-week data, including initial aflibercept protein levels anticipated in the third quarter 2023
  • Preliminary efficacy and safety data anticipated in the fourth quarter of 2023
  • Granted Fast Track Designation by the U.S. FDA
  • Received PRIME designation by the European Medicines Agency and the Innovation Passport under the Innovative Licensing and Access Pathway from the United Kingdom’s Medicines and Healthcare Products Regulatory Agency

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-2.5%

Avg return

30 days after

45%

17 / 38 earnings

Positive

+12.5%

Q3 2022

Best reaction

-15.5%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-0.9%-1.2%
Q2 2025+10.8%+27.9%+41.4%
Q1 2025-1.0%+21.0%+19.5%
Q4 2024-5.8%-15.4%-41.0%
Q3 2024+4.2%+8.4%-18.5%
Q2 2024+3.0%+4.7%+7.3%
Q1 2024-5.2%-9.3%-25.1%
Q4 2023-2.9%-5.3%-33.1%
Q3 2023+1.8%-3.4%+0.0%
Q2 2023+2.2%-3.8%-7.1%
Q1 2023-4.6%-4.1%+89.3%
Q4 2022-4.5%-6.7%+3.6%
Q3 2022+12.5%+3.2%-9.6%
Q2 2022-4.5%-8.6%-25.0%
Q1 2022-14.1%-13.5%+2.7%
Q4 2021-2.9%-5.8%-20.3%
Q3 2021-5.6%-1.3%-24.9%
Q2 2021+6.9%
Q1 2021+3.3%
Q4 2020-5.3%
Q3 2020-7.8%
Q2 2020-15.5%
Q1 2020-1.9%
Q4 2019+11.6%
Q3 2019+8.9%
Q2 2019-1.3%
Q1 2019-3.7%
Q4 2018+2.8%
Q3 2018+1.9%
Q2 2018+10.9%
Q1 2018+3.6%
Q4 2017-4.1%
Q3 2017-6.3%
Q2 2017-2.0%
Q1 2017-1.8%
Q3 2016+11.9%
Q2 2016+2.3%
Q3 2014+4.5%
Q2 2014
Q1 2014
Q4 2014
Q3 2013
Q2 2013
Q1 2013

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