NASDAQ$ADVM

Adverum Biotechnologies Inc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Announced financial results for the second quarter ended June 30, 2022.

Adverum Biotechnologies reported a net loss of $43.8 million for the second quarter of 2022. The company's cash runway is expected to extend into 2025 following a corporate restructuring.

  • Dosing first Phase 2 LUNA trial participant with ixoberogene soroparvovec (Ixo-vec, formerly referred to as ADVM-022) on track for the third quarter of 2022 and preliminary data anticipated throughout 2023
  • Cash runway extended into 2025 to prioritize the clinical development of Ixo-vec and provide additional resources beyond anticipated one-year topline results of the Phase 2 LUNA trial
  • Submitted Investigational New Drug (IND) amendment to the FDA to initiate its Phase 2 LUNA trial of Ixo-vec.
  • The European Medicines Agency (EMA) granted Priority Medicines (PRIME) designation for ADVM-022 in wet AMD.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$4.40

Previous: -$4.50+2.2%
Stock comp in R&D

$1.8M

No prior period
Stock comp in G&A

$3.1M

No prior period
Capital Expenditures

-$10.8M

Previous: -$5.05M-113.9%
Free Cash Flow

-$68.6M

Previous: -$61.3M-12.0%
Net Income

-$43.8M

Previous: -$44.3M+1.3%
Operating Income

-$44M

Previous: -$44.5M+1.2%
Cash & Equivalents

$236M

Previous: $364M-35.2%
Total Assets

$375M

Previous: $526M-28.7%
Stock-Based Comp

$4.94M

Previous: $8.23M-40.0%

Revenue & EPS history

Adverum · Revenue · Quarterly

$0

Q2 2022
Beat estimate in 1 of 4 quarters(25%)
ActualEstimate

Forward guidance

Adverum plans to dose the first patient in a Phase 2 LUNA trial of Ixo-vec in wet AMD in the third quarter of 2022, with preliminary LUNA data anticipated throughout 2023. The company expects its cash position to fund operations into 2025.

Tailwinds

  • Dosing first Phase 2 LUNA trial participant with ixoberogene soroparvovec (Ixo-vec, formerly referred to as ADVM-022) on track for the third quarter of 2022
  • Preliminary LUNA data anticipated throughout 2023
  • Cash runway extended into 2025
  • Prioritizing Ixo-vec’s clinical development
  • Focusing its pipeline strategy on certain highly prevalent ocular diseases

Headwinds

  • Risks inherent to Adverum’s novel technology
  • Difficult to predict the timing of commencement and completion of clinical trials
  • Regulatory uncertainties
  • Enrollment uncertainties
  • Potential for future complications or side effects in connection with use of Ixo-vec

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

+0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-2.5%

Avg return

30 days after

45%

17 / 38 earnings

Positive

+12.5%

Q3 2022

Best reaction

-15.5%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-0.9%-1.2%
Q2 2025+10.8%+27.9%+41.4%
Q1 2025-1.0%+21.0%+19.5%
Q4 2024-5.8%-15.4%-41.0%
Q3 2024+4.2%+8.4%-18.5%
Q2 2024+3.0%+4.7%+7.3%
Q1 2024-5.2%-9.3%-25.1%
Q4 2023-2.9%-5.3%-33.1%
Q3 2023+1.8%-3.4%+0.0%
Q2 2023+2.2%-3.8%-7.1%
Q1 2023-4.6%-4.1%+89.3%
Q4 2022-4.5%-6.7%+3.6%
Q3 2022+12.5%+3.2%-9.6%
Q2 2022-4.5%-8.6%-25.0%
Q1 2022-14.1%-13.5%+2.7%
Q4 2021-2.9%-5.8%-20.3%
Q3 2021-5.6%-1.3%-24.9%
Q2 2021+6.9%
Q1 2021+3.3%
Q4 2020-5.3%
Q3 2020-7.8%
Q2 2020-15.5%
Q1 2020-1.9%
Q4 2019+11.6%
Q3 2019+8.9%
Q2 2019-1.3%
Q1 2019-3.7%
Q4 2018+2.8%
Q3 2018+1.9%
Q2 2018+10.9%
Q1 2018+3.6%
Q4 2017-4.1%
Q3 2017-6.3%
Q2 2017-2.0%
Q1 2017-1.8%
Q3 2016+11.9%
Q2 2016+2.3%
Q3 2014+4.5%
Q2 2014
Q1 2014
Q4 2014
Q3 2013
Q2 2013
Q1 2013

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