NASDAQ$ADVM

Adverum Biotechnologies Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Adverum reported financial results for the fourth quarter and full year 2023 and provided pipeline highlights and corporate updates.

Adverum Biotechnologies reported its Q4 and full-year 2023 financial results, highlighting progress in the development of Ixo-vec and the completion of a $127.5 million private placement financing.

  • Presented preliminary Ixo-vec LUNA trial data at Macula Society, showing potential best-in-class clinical activity and encouraging safety profile in wet AMD patients.
  • Completed a $127.5 million private placement financing to extend cash runway into late 2025.
  • Approved a 1-for-10 reverse stock split, effective March 21, 2024.
  • Appointed Romuald Corbau, Ph.D. as Chief Scientific Officer.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$2.30

Previous: -$3.30+30.3%
R&D expenses

$15.3M

No prior period
G&A expenses

$11.7M

No prior period
Capital Expenditures

-$192K

Previous: $185K-203.8%
Net Income

-$23.7M

Previous: -$32.7M+27.5%
Operating Income

-$26.2M

Previous: -$33.9M+22.9%
Gross Profit

-$1.01M

No prior period
R&D Expense

$15.1M

No prior period
Stock-Based Comp

$4.15M

Previous: $5.25M-21.0%

Revenue & EPS history

Adverum · Revenue · Quarterly

$0

Q4 2023
Beat estimate in 1 of 4 quarters(25%)
ActualEstimate

Forward guidance

Adverum anticipates continued regulatory interactions, the presentation of LUNA 26-week interim analysis in mid-2024, and initiation of a Phase 3 trial in H1 2025.

Tailwinds

  • Continued FDA and EMA formal and informal regulatory interactions
  • LUNA 26-week interim analysis
  • Initiation of Phase 3 trial in H1 2025
  • Positive preliminary efficacy and safety data from the ongoing LUNA Phase 2 trial of Ixo-vec
  • Financing is expected to extend Adverum’s cash runway into late 2025

Headwinds

  • Risks associated with market conditions
  • Risks inherent to clinical trials
  • Uncertainties facing Adverum are set forth under the caption “Risk Factors” and elsewhere in Adverum’s Securities and Exchange Commission (SEC) filings and reports
  • The current standard of care requires frequent life-long repeated bolus injections of anti-VEGF in the eye.
  • Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-2.5%

Avg return

30 days after

45%

17 / 38 earnings

Positive

+12.5%

Q3 2022

Best reaction

-15.5%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-0.9%-1.2%
Q2 2025+10.8%+27.9%+41.4%
Q1 2025-1.0%+21.0%+19.5%
Q4 2024-5.8%-15.4%-41.0%
Q3 2024+4.2%+8.4%-18.5%
Q2 2024+3.0%+4.7%+7.3%
Q1 2024-5.2%-9.3%-25.1%
Q4 2023-2.9%-5.3%-33.1%
Q3 2023+1.8%-3.4%+0.0%
Q2 2023+2.2%-3.8%-7.1%
Q1 2023-4.6%-4.1%+89.3%
Q4 2022-4.5%-6.7%+3.6%
Q3 2022+12.5%+3.2%-9.6%
Q2 2022-4.5%-8.6%-25.0%
Q1 2022-14.1%-13.5%+2.7%
Q4 2021-2.9%-5.8%-20.3%
Q3 2021-5.6%-1.3%-24.9%
Q2 2021+6.9%
Q1 2021+3.3%
Q4 2020-5.3%
Q3 2020-7.8%
Q2 2020-15.5%
Q1 2020-1.9%
Q4 2019+11.6%
Q3 2019+8.9%
Q2 2019-1.3%
Q1 2019-3.7%
Q4 2018+2.8%
Q3 2018+1.9%
Q2 2018+10.9%
Q1 2018+3.6%
Q4 2017-4.1%
Q3 2017-6.3%
Q2 2017-2.0%
Q1 2017-1.8%
Q3 2016+11.9%
Q2 2016+2.3%
Q3 2014+4.5%
Q2 2014
Q1 2014
Q4 2014
Q3 2013
Q2 2013
Q1 2013

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