NASDAQ$ACAD

ACADIA Pharmaceuticals Inc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Reported a net sales increase of 17% year-over-year, NDA submitted for trofinetide for the treatment of Rett syndrome.

Acadia Pharmaceuticals reported a 17% increase in NUPLAZID net sales compared to Q2 2021. The company submitted an NDA for trofinetide for Rett syndrome and is well-positioned for long-term growth with a strong balance sheet and a focus on strategic business development.

  • NUPLAZID net sales increased by 17% year-over-year.
  • Submitted an NDA for trofinetide for the treatment of Rett syndrome.
  • Discontinued the development of ACP-044 and ACP-319.
  • Net loss was $34.0 million, or $0.21 per common share.

Headline financials

Total Revenue

$135M

Previous: $115M+16.8%
EPS (adj)

-$0.21

Previous: -$0.27+22.2%
Capital Expenditures

$0.00

Previous: -$1.12M+100.0%
Free Cash Flow

-$34M

Previous: -$45M+24.4%
Net Income

-$34M

Previous: -$43.9M+22.5%
Operating Income

-$33.7M

Previous: -$43.7M+23.0%
Gross Profit

$132M

Previous: $113M+17.0%
Cash & Equivalents

$436M

Previous: $557M-21.6%
Total Assets

$613M

Previous: $724M-15.4%
Stock-Based Comp

$20.5M

Previous: $22M-6.8%

Revenue & EPS history

ACADIA · Revenue · Quarterly

$135M

Q2 2022+16.8%vs Q2 2021
Beat estimate in 7 of 15 quarters(47%)
ActualEstimate

Revenue by segment

ACADIA · $135M total across 1 segment · Q2 2022

  • NUPLAZID
    $135M+16.8%

Forward guidance

Acadia has updated its 2022 financial guidance.

Tailwinds

  • NUPLAZID net sales guidance is updated to $510 to $540 million.
  • GAAP R&D guidance is updated to $340 to $360 million, which includes approximately $25 million of stock-based compensation expense.
  • GAAP SG&A guidance of $360 to $380 million is reiterated, which includes approximately $45 million of stock-based compensation expense.
  • Developing pimavanserin in other neuropsychiatric conditions
  • Advancing breakthroughs in neuroscience to elevate life

Headwinds

  • Uncertainty of future commercial sales and related items that would impact net sales during 2022
  • Risks and uncertainties inherent in drug development, approval and commercialization
  • Past results of clinical trials may not be indicative of future trial results
  • Discontinuing the development of ACP-044 in acute and chronic pain
  • Discontinuing ACP-319 an M1 PAM modulator

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

-0.9%

Avg return

Earnings day

-0.4%

Avg return

5 days after

-1.6%

Avg return

30 days after

42%

27 / 65 earnings

Positive

+23.7%

Q3 2016

Best reaction

-22.9%

Q4 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.9%-2.5%-3.6%
Q4 2025-1.4%-9.9%-16.9%
Q3 2025-2.9%+6.2%+22.9%
Q1 2025+14.4%+16.1%+48.4%
Q4 2024+1.8%-3.9%-10.2%
Q3 2024+14.7%+21.8%+15.2%
Q2 2024-17.6%-15.1%-11.9%
Q1 2024-11.8%-12.0%-13.7%
Q4 2023-8.3%-7.3%-28.6%
Q3 2023+5.0%+2.5%-1.4%
Q2 2023-6.0%-7.4%-4.0%
Q1 2023-2.3%-2.1%+12.3%
Q4 2022+9.4%+7.5%+0.3%
Q3 2022-6.6%-8.6%-0.6%
Q2 2022-1.3%-0.2%+2.5%
Q1 2022-4.9%-17.3%-9.6%
Q4 2021-2.2%-6.2%-4.8%
Q3 2021+7.7%+3.1%+8.8%
Q2 2021-11.0%-11.4%-22.4%
Q1 2021+7.3%+7.7%+21.4%
Q4 2020-4.9%-0.4%-48.0%
Q3 2020+4.2%+7.4%+16.4%
Q2 2020+0.3%-5.1%-12.1%
Q1 2020+5.3%+2.5%-5.3%
Q4 2019-3.9%+7.6%-4.5%
Q3 2019+0.4%+0.4%+7.2%
Q2 2019+14.7%+14.4%+10.6%
Q1 2019+6.0%+11.4%-0.2%
Q4 2018+7.5%+12.0%+12.2%
Q3 2018-7.7%-12.9%-12.7%
Q2 2018-2.0%+0.7%-1.1%
Q1 2018+15.6%+15.8%+14.3%
Q4 2017-22.9%-26.8%-30.5%
Q3 2017-9.6%-12.1%-7.6%
Q2 2017+8.6%+2.1%+17.1%
Q1 2017-8.6%-8.7%-17.8%
Q4 2016-8.1%-7.4%-14.4%
Q3 2016+23.7%+32.8%+24.9%
Q2 2016-1.8%-10.3%-15.0%
Q1 2016+0.4%
Q4 2015+2.2%
Q3 2015-13.1%
Q2 2015-17.8%
Q1 2015+3.2%
Q4 2014+1.5%
Q3 2014-0.7%
Q2 2014+3.1%
Q1 2014-8.4%
Q4 2013-4.8%
Q3 2013-7.8%
Q2 2013-5.6%
Q1 2013-4.4%
Q4 2012-6.0%
Q3 2012+11.0%
Q2 2012-0.7%
Q1 2012+0.0%
Q4 2011+0.6%
Q4 2009+0.6%
Q3 2011-5.0%
Q4 2010-2.9%
Q2 2011-2.9%
Q1 2011-4.1%
Q3 2010+1.4%
Q2 2010-7.5%
Q1 2010+11.5%

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