NASDAQ$ACAD

ACADIA Pharmaceuticals Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Acadia reported Q4 2023 financial results, achieving revenue growth driven by DAYBUE and NUPLAZID sales, and advancing its pipeline with Phase 3 and Phase 2 trials.

Acadia Pharmaceuticals reported a transformational year in 2023, achieving 40% revenue growth driven by the launch of DAYBUE and growth in the NUPLAZID franchise. In the fourth quarter, the company advanced its pipeline with the initiation of Phase 3 and Phase 2 trials and reported net income of $45.8 million.

  • Total net product sales of $726.4 million for 2023, reflecting 40% revenue growth.
  • DAYBUE net product sales of $87.1 million for the fourth quarter and $177.2 million for the full year 2023.
  • NUPLAZID net product sales of $143.9 million for the fourth quarter and $549.2 million for the full year 2023.
  • Initiated a Phase 3 trial of ACP-101 in Prader-Willi syndrome and a Phase 2/Phase 3 program for ACP-204 in Alzheimer’s disease psychosis in Q4 2023.

Headline financials

Total Revenue

$231M

Previous: $136M+69.3%
EPS (adj)

$0.28

Previous: -$0.26+207.7%
Total Revenue Growth

231041000.0%

No prior period
NUPLAZID Non-GAAP Growth

143900000.0%

No prior period
DAYBUE Sales Growth

87100000.0%

No prior period
Net Income

$45.8M

Previous: -$41.7M+209.8%
Operating Income

$34.9M

Previous: -$46.1M+175.9%
Gross Profit

$213M

Previous: $134M+59.0%
R&D Expense

$66.7M

No prior period
Stock-Based Comp

$18M

Previous: $14.4M+25.0%

Revenue & EPS history

ACADIA · Revenue · Quarterly

$231M

Q4 2023+69.3%vs Q4 2022
Beat estimate in 7 of 15 quarters(47%)
ActualEstimate

Revenue by segment

ACADIA · $212M total across 2 segments · Q3 2023

  • NUPLAZID
    $145M+10.8%
  • DAYBUE
    $66.9M

Forward guidance

Acadia provided full year 2024 financial guidance.

Tailwinds

  • DAYBUE net product sales in the range of $370 to $420 million.
  • NUPLAZID net product sales in the range of $560 to $590 million.
  • GAAP R&D expense in the range of $305 to $325 million.
  • GAAP SG&A expense in the range of $455 to $480 million.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-0.9%

Avg return

Earnings day

-0.4%

Avg return

5 days after

-1.6%

Avg return

30 days after

42%

27 / 65 earnings

Positive

+23.7%

Q3 2016

Best reaction

-22.9%

Q4 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.9%-2.5%-3.6%
Q4 2025-1.4%-9.9%-16.9%
Q3 2025-2.9%+6.2%+22.9%
Q1 2025+14.4%+16.1%+48.4%
Q4 2024+1.8%-3.9%-10.2%
Q3 2024+14.7%+21.8%+15.2%
Q2 2024-17.6%-15.1%-11.9%
Q1 2024-11.8%-12.0%-13.7%
Q4 2023-8.3%-7.3%-28.6%
Q3 2023+5.0%+2.5%-1.4%
Q2 2023-6.0%-7.4%-4.0%
Q1 2023-2.3%-2.1%+12.3%
Q4 2022+9.4%+7.5%+0.3%
Q3 2022-6.6%-8.6%-0.6%
Q2 2022-1.3%-0.2%+2.5%
Q1 2022-4.9%-17.3%-9.6%
Q4 2021-2.2%-6.2%-4.8%
Q3 2021+7.7%+3.1%+8.8%
Q2 2021-11.0%-11.4%-22.4%
Q1 2021+7.3%+7.7%+21.4%
Q4 2020-4.9%-0.4%-48.0%
Q3 2020+4.2%+7.4%+16.4%
Q2 2020+0.3%-5.1%-12.1%
Q1 2020+5.3%+2.5%-5.3%
Q4 2019-3.9%+7.6%-4.5%
Q3 2019+0.4%+0.4%+7.2%
Q2 2019+14.7%+14.4%+10.6%
Q1 2019+6.0%+11.4%-0.2%
Q4 2018+7.5%+12.0%+12.2%
Q3 2018-7.7%-12.9%-12.7%
Q2 2018-2.0%+0.7%-1.1%
Q1 2018+15.6%+15.8%+14.3%
Q4 2017-22.9%-26.8%-30.5%
Q3 2017-9.6%-12.1%-7.6%
Q2 2017+8.6%+2.1%+17.1%
Q1 2017-8.6%-8.7%-17.8%
Q4 2016-8.1%-7.4%-14.4%
Q3 2016+23.7%+32.8%+24.9%
Q2 2016-1.8%-10.3%-15.0%
Q1 2016+0.4%
Q4 2015+2.2%
Q3 2015-13.1%
Q2 2015-17.8%
Q1 2015+3.2%
Q4 2014+1.5%
Q3 2014-0.7%
Q2 2014+3.1%
Q1 2014-8.4%
Q4 2013-4.8%
Q3 2013-7.8%
Q2 2013-5.6%
Q1 2013-4.4%
Q4 2012-6.0%
Q3 2012+11.0%
Q2 2012-0.7%
Q1 2012+0.0%
Q4 2011+0.6%
Q4 2009+0.6%
Q3 2011-5.0%
Q4 2010-2.9%
Q2 2011-2.9%
Q1 2011-4.1%
Q3 2010+1.4%
Q2 2010-7.5%
Q1 2010+11.5%

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