NASDAQ$TXG

10X Genomics Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

10x Genomics reported Q3 2025 revenue of $149.0M with a net loss of $27.5M ($0.22 per share).

Revenue was $149.0 million, roughly flat year over year, as Chromium and Xenium platforms faced mixed academic and biopharma demand. Net loss was $27.5 million, or $(0.22) per share.

  • Q3 revenue $149.0M.
  • Net loss $27.5M; EPS $(0.22).
  • Single-cell and spatial biology instruments and consumables.
  • Installed base and consumable pull-through drive recurring revenue.

Headline financials

Total Revenue

$149M

Previous: $152M-1.7%
EPS (adj)

-$0.22

Previous: -$0.30+26.7%
Gross Margin

0.7%

Previous: 0.7%-4.3%
Stock-based Compensation Expense

$25.3M

Previous: $33.9M-25.5%
Capital Expenditures

-$4.16M

Previous: -$9.68M+57.0%
Net Income

-$27.5M

Previous: -$35.8M+23.2%
Operating Income

-$32.2M

Previous: -$41.5M+22.3%
Gross Profit

$100M

Previous: $106M-5.7%

Revenue & EPS history

10X Genomics · Revenue · Quarterly

$149M

Q3 2025-1.7%vs Q3 2024
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Revenue by segment

10X Genomics · $149M total across 4 segments · Q3 2023

  • Single Cell Consumables
    $100M
  • Spatial Instruments
    $22.7M
  • Spatial Consumables
    $14.1M
  • Single Cell Instruments
    $12.2M

Forward guidance

The filing discusses 10x Genomics's outlook, capital priorities, and key risks, including guidance or operating targets where disclosed.

Tailwinds

  • 10x Genomics cites execution and demand supporting the near-term outlook.
  • Balance sheet and capital allocation remain focal points in the filing.

Headwinds

  • GAAP profitability remained under pressure in the quarter.
  • Macro, competition, and input costs may pressure margins quarter to quarter.
  • One-time items and segment mix can affect comparability versus prior periods.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+2.1%

Avg return

Earnings day

+2.3%

Avg return

5 days after

+2.0%

Avg return

30 days after

58%

15 / 26 earnings

Positive

+17.3%

Q3 2025

Best reaction

-21.9%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.6%-5.9%+38.4%
Q4 2025+3.5%+11.8%+7.3%
Q3 2025+17.3%+28.4%+36.7%
Q1 2025+1.3%+5.7%+9.2%
Q4 2024-0.5%+0.6%-13.8%
Q3 2024+4.0%+3.0%-2.4%
Q2 2024+12.7%+18.8%+18.8%
Q1 2024-5.2%-3.2%-21.1%
Q4 2023+0.8%-1.3%-24.4%
Q3 2023+15.7%+13.7%+33.3%
Q2 2023-4.5%-7.7%-7.9%
Q1 2023+5.9%+5.5%+5.7%
Q4 2022+14.8%+15.2%+7.5%
Q3 2022+13.0%+9.5%+38.1%
Q2 2022+5.4%+13.2%-24.0%
Q1 2022-0.5%-6.4%-10.6%
Q4 2021-15.0%-14.4%-26.7%
Q3 2021+12.7%+7.7%-14.9%
Q2 2021-1.8%-3.3%+3.7%
Q1 2021-21.9%-27.1%-2.6%
Q4 2020-3.1%-7.1%-7.6%
Q3 2020+1.8%+3.3%+11.4%
Q2 2020+0.6%+6.0%+17.1%
Q1 2020-0.4%-6.0%+3.1%
Q4 2019-2.1%-11.4%-40.6%
Q3 2019+3.1%+10.3%+17.3%
Q2 2019
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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