NASDAQ$TSHA

Taysha Gene Therapies Inc · Q3 2023 earnings

Q3 2023 earnings · · Investor relations

Briefing

Taysha Gene Therapies reported financial results for the third quarter ended September 30, 2023, and provided corporate and clinical updates.

Taysha Gene Therapies reported a net loss of $117.1 million for the third quarter of 2023, driven by a non-cash expense related to a change in the fair value of warrant liability. The company's cash and cash equivalents totaled $164.3 million as of September 30, 2023, expected to fund operations into 2026.

  • Data from first adult patient in REVEAL Phase 1/2 trial showed TSHA-102 was well-tolerated with sustained improvement across key efficacy measures.
  • Data from second adult patient showed TSHA-102 was well-tolerated with improvement across key efficacy measures.
  • IDMC provided clearance to dose third adult patient based on available data; dosing expected in Q4 2023/Q1 2024.
  • Entered into loan and security agreement with Trinity Capital that extends cash runway into 2026 and includes no financial covenants or warrants.

Headline financials

Total Revenue

$4.75M

Previous: $0.00
EPS (adj)

-$0.93

Previous: -$0.64-45.3%
R&D expenses

$11.8M

Previous: $16.4M-28.0%
G&A expenses

$8.6M

Previous: $8.7M-1.1%
Capital Expenditures

-$3.85M

Previous: $2.02M-290.7%
Free Cash Flow

-$121M

Previous: -$30.7M-294.3%
Net Income

-$117M

Previous: -$26.3M-345.1%
Operating Income

-$16.3M

Previous: -$25.1M+35.2%
Gross Profit

$4.75M

No prior period
Cash & Equivalents

$164M

Previous: $34.3M+378.9%
Total Assets

$196M

Previous: $111M+75.6%
R&D Expense

$11.8M

No prior period
Stock-Based Comp

$2.04M

Previous: $4.47M-54.4%

Revenue & EPS history

Taysha Gene Therapies · Revenue · Quarterly

$4.75M

Q3 2023
Beat estimate in 8 of 11 quarters(73%)
ActualEstimate

Forward guidance

Taysha anticipates several milestones in the near term, including dosing the third adult patient in the REVEAL trial, further updates on clinical data from the low dose cohort, dosing the first pediatric Rett syndrome patient in the U.S., and a response from the U.K. MHRA regarding the Clinical Trial Application for TSHA-102.

Tailwinds

  • Dosing of third adult patient and completion of dosing in cohort one (low dose) in the adult trial in Canada anticipated in the fourth quarter of 2023/first quarter of 2024
  • Further updates on available clinical data from the low dose cohort expected in the first quarter of 2024
  • Dosing of first pediatric Rett syndrome patient in the U.S. anticipated in the first quarter of 2024
  • U.K. Medicines and Healthcare products Regulatory Agency (MHRA) response to Clinical Trial Application (CTA) for TSHA-102 in pediatric patients with Rett syndrome expected by year-end 2023

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2023

Historical avgQ3 2023

+10.9%

Avg return

Earnings day

+11.7%

Avg return

5 days after

+18.2%

Avg return

30 days after

52%

12 / 23 earnings

Positive

+195.0%

Q2 2023

Best reaction

-16.0%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-3.5%-6.3%
Q1 2026+0.6%-1.6%-20.9%
Q3 2025-5.9%-8.9%+18.3%
Q2 2025+5.4%+6.5%+17.4%
Q1 2025+8.1%+23.6%+7.2%
Q4 2024-4.7%-4.7%+13.5%
Q3 2024-5.0%-4.6%-13.4%
Q2 2024+9.1%+7.7%+11.0%
Q1 2024+29.6%+28.7%+73.7%
Q4 2023+39.0%+52.6%+13.1%
Q3 2023+26.3%+27.8%+16.5%
Q2 2023+195.0%+159.8%+312.7%
Q1 2023-10.5%-7.7%+14.7%
Q4 2022-6.5%+14.8%-3.9%
Q3 2022-5.5%+9.0%+2.5%
Q2 2022-16.0%-16.4%-29.9%
Q1 2022-4.1%-19.5%-12.5%
Q4 2021+3.1%+8.5%-40.5%
Q3 2021+0.2%-3.1%-9.3%
Q2 2021+0.7%-2.6%+20.1%
Q1 2021-0.7%+2.0%+19.9%
Q4 2020-7.2%-0.2%-19.9%
Q3 2020+2.2%+4.0%+10.3%

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