NASDAQ$TSHA

Taysha Gene Therapies Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Reported financial results for the third quarter ended September 30, 2022 and provided a corporate update.

Taysha Gene Therapies reported a net loss of $26.3 million for the third quarter of 2022. They secured a $50 million strategic investment from Astellas Pharma and proceeds from a follow-on offering, extending their cash runway into the first quarter of 2024.

  • Astellas Pharma made a $50 million strategic investment to support the development of TSHA-120 in giant axonal neuropathy (GAN) and TSHA-102 in Rett syndrome.
  • Proceeds from follow-on offering along with Astellas strategic investment extends cash runway into first quarter of 2024
  • Type B end-of-Phase 2 meeting with FDA for TSHA-120 in GAN scheduled for December 13, 2022
  • Preliminary clinical safety and efficacy data for TSHA-102 from the first cohort of adult patients with Rett syndrome and initiation of female pediatric study expected in first half of 2023

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$0.64

Previous: -$1.35+52.6%
R&D expenses

$16.4M

Previous: $39.5M-58.5%
G&A expenses

$8.7M

Previous: $11.2M-22.3%
Capital Expenditures

$2.02M

Previous: $3.5M-42.3%
Free Cash Flow

-$30.7M

Previous: -$35.4M+13.4%
Net Income

-$26.3M

Previous: -$51.2M+48.6%
Operating Income

-$25.1M

Previous: -$50.7M+50.5%
Cash & Equivalents

$34.3M

Previous: $189M-81.8%
Total Assets

$111M

Previous: $241M-53.8%
Stock-Based Comp

$4.47M

Previous: $5.09M-12.1%

Revenue & EPS history

Taysha Gene Therapies · Revenue · Quarterly

$0

Q3 2022
Beat estimate in 8 of 11 quarters(73%)
ActualEstimate

Forward guidance

Taysha Gene Therapies anticipates key milestones in 2023, including a regulatory update for TSHA-120 in GAN and preliminary clinical data for TSHA-102 in Rett syndrome.

Tailwinds

  • Regulatory update for TSHA-120 in GAN following receipt of formal meeting minutes from the Type B end-of-Phase 2 meeting with FDA expected in mid-January 2023
  • Preliminary clinical safety and efficacy data for TSHA-102 from the entire first cohort of adult patients with Rett syndrome expected in H1 2023
  • Initiation of Phase 1/2 trial for TSHA-102 in female pediatric patients with Rett syndrome in H1 2023

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

+10.9%

Avg return

Earnings day

+11.7%

Avg return

5 days after

+18.2%

Avg return

30 days after

52%

12 / 23 earnings

Positive

+195.0%

Q2 2023

Best reaction

-16.0%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-3.5%-6.3%
Q1 2026+0.6%-1.6%-20.9%
Q3 2025-5.9%-8.9%+18.3%
Q2 2025+5.4%+6.5%+17.4%
Q1 2025+8.1%+23.6%+7.2%
Q4 2024-4.7%-4.7%+13.5%
Q3 2024-5.0%-4.6%-13.4%
Q2 2024+9.1%+7.7%+11.0%
Q1 2024+29.6%+28.7%+73.7%
Q4 2023+39.0%+52.6%+13.1%
Q3 2023+26.3%+27.8%+16.5%
Q2 2023+195.0%+159.8%+312.7%
Q1 2023-10.5%-7.7%+14.7%
Q4 2022-6.5%+14.8%-3.9%
Q3 2022-5.5%+9.0%+2.5%
Q2 2022-16.0%-16.4%-29.9%
Q1 2022-4.1%-19.5%-12.5%
Q4 2021+3.1%+8.5%-40.5%
Q3 2021+0.2%-3.1%-9.3%
Q2 2021+0.7%-2.6%+20.1%
Q1 2021-0.7%+2.0%+19.9%
Q4 2020-7.2%-0.2%-19.9%
Q3 2020+2.2%+4.0%+10.3%

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