NASDAQ$TSHA

Taysha Gene Therapies Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Taysha reported Q1 2026 with no product revenue, a net loss of $42.4M, and diluted loss per share of $0.12.

The gene-therapy company had no product revenue in Q1 2026 (versus $2.3 million of collaboration revenue a year ago). Net loss was $42.4 million, or $0.12 per diluted share, as R&D rose to $33.8 million. Interest income and fair-value changes on the term loan partially offset operating spend.

  • No product revenue; R&D $33.8M.
  • Net loss $(42.4)M; diluted EPS $(0.12).
  • Share count rose to ~367M basic shares.
  • Cash/investments fund CNS gene-therapy programs.

Headline financials

Total Revenue

$0.00

Previous: $2.3M-100.0%
EPS (adj)

-$0.12

Previous: -$0.08-50.0%
Capital Expenditures

-$24K

No prior period
Free Cash Flow

-$40.9M

No prior period
Net Income

-$42.4M

Previous: -$21.5M-97.0%
Operating Income

-$43.5M

Previous: -$21.4M-103.0%
Gross Profit

$0.00

No prior period
Cash & Equivalents

$277M

No prior period
Total Assets

$300M

No prior period

Revenue & EPS history

Taysha Gene Therapies · Revenue · Quarterly

$0

Q1 2026-100%vs Q1 2025
Beat estimate in 8 of 11 quarters(73%)
ActualEstimate

Forward guidance

Clinical milestones for lead programs are the forward indicators; no commercial revenue guidance in the filing.

Tailwinds

  • Loss per share stable despite higher R&D.
  • Interest income supports net loss trajectory.
  • Pipeline focused on monogenic CNS diseases.

Headwinds

  • No near-term product sales.
  • Clinical/regulatory risk on gene therapies.
  • Financing needs if trials expand.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+10.9%

Avg return

Earnings day

+11.7%

Avg return

5 days after

+18.2%

Avg return

30 days after

52%

12 / 23 earnings

Positive

+195.0%

Q2 2023

Best reaction

-16.0%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-3.5%-6.3%
Q1 2026+0.6%-1.6%-20.9%
Q3 2025-5.9%-8.9%+18.3%
Q2 2025+5.4%+6.5%+17.4%
Q1 2025+8.1%+23.6%+7.2%
Q4 2024-4.7%-4.7%+13.5%
Q3 2024-5.0%-4.6%-13.4%
Q2 2024+9.1%+7.7%+11.0%
Q1 2024+29.6%+28.7%+73.7%
Q4 2023+39.0%+52.6%+13.1%
Q3 2023+26.3%+27.8%+16.5%
Q2 2023+195.0%+159.8%+312.7%
Q1 2023-10.5%-7.7%+14.7%
Q4 2022-6.5%+14.8%-3.9%
Q3 2022-5.5%+9.0%+2.5%
Q2 2022-16.0%-16.4%-29.9%
Q1 2022-4.1%-19.5%-12.5%
Q4 2021+3.1%+8.5%-40.5%
Q3 2021+0.2%-3.1%-9.3%
Q2 2021+0.7%-2.6%+20.1%
Q1 2021-0.7%+2.0%+19.9%
Q4 2020-7.2%-0.2%-19.9%
Q3 2020+2.2%+4.0%+10.3%

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