NASDAQ$PRAX

Praxis Precision Medicines I · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Praxis Precision Medicines reported financial results and provided a corporate update.

Praxis Precision Medicines reported a net loss of $51.9 million for Q3 2024, with research and development expenses increasing to $41.9 million. The company's cash, cash equivalents, and marketable securities totaled $411.2 million as of September 30, 2024, providing a runway into 2027. Key clinical programs, including ulixacaltamide, vormatrigine, and relutrigine, are advancing towards registrational readiness.

  • Advanced relutrigine into late-stage development, marking a third molecule with blockbuster potential.
  • Finalized the operational plan to complete the interim analysis for Essential3 Study 1 for ulixacaltamide in mid-Q1 2025.
  • Progressed the SCN2A/8A program to registrational stage and expanding studies to cover a broader range of DEEs based on positive EMBOLD cohort 1 results.
  • The EMPOWER observational study started enrolling patients in the third quarter of 2024 and has already enrolled over 1,000 patients.

Headline financials

Total Revenue

$302K

Previous: $468K-35.5%
EPS

-$2.75

Previous: -$2.70-1.9%
Capital Expenditures

$0.00

Previous: $0.00
Free Cash Flow

-$51.9M

Previous: -$24.6M-110.7%
Net Income

-$51.9M

Previous: -$24.6M-110.7%
Operating Income

-$56.8M

Previous: -$25.5M-122.7%
Gross Profit

$302K

Previous: $468K-35.5%
R&D Expense

$41.9M

Previous: $17.3M+142.6%
Stock-Based Comp

$12.4M

Previous: $5.76M+115.7%

Revenue & EPS history

Praxis · Revenue · Quarterly

$302K

Q3 2024-35.5%vs Q3 2023
Beat estimate in 2 of 8 quarters(25%)
ActualEstimate

Revenue by segment

Praxis · $500K total across 1 segment · Q3 2023

  • Collaboration Revenue
    $500K

Forward guidance

Praxis Precision Medicines is set to build on its momentum, advancing all four clinical programs towards registrational readiness in 2025.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

-0.3%

Avg return

Earnings day

+3.3%

Avg return

5 days after

-4.0%

Avg return

30 days after

57%

13 / 23 earnings

Positive

+22.3%

Q2 2022

Best reaction

-40.6%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.7%-6.4%-22.2%
Q4 2025+0.5%+4.2%-9.3%
Q3 2025-4.7%-2.2%+44.4%
Q1 2025+0.2%-3.5%+16.3%
Q4 2024-40.6%-41.8%-40.6%
Q3 2024+3.6%+16.6%-4.0%
Q2 2024-1.1%+2.0%+13.3%
Q1 2024-5.9%-6.9%-15.8%
Q4 2023+6.3%+2.3%-7.3%
Q3 2023+1.4%-0.6%+21.6%
Q2 2023+10.8%+17.0%+43.9%
Q1 2023-2.8%-1.9%-7.7%
Q4 2022-4.2%-13.0%-77.0%
Q3 2022-12.5%-11.2%-13.3%
Q2 2022+22.3%+33.2%-3.4%
Q1 2022+14.0%+28.1%-77.7%
Q4 2021-1.9%-4.2%-22.9%
Q3 2021+2.4%+2.0%-17.1%
Q2 2020+12.7%+35.9%+42.8%
Q2 2021+12.7%+35.9%+42.8%
Q1 2021-16.4%-16.1%-20.2%
Q4 2020-6.8%-11.5%-34.0%
Q3 2020+2.3%+18.2%+54.7%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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