NASDAQ$PRAX

Praxis Precision Medicines I · Q1 2021 earnings

Q1 2021 earnings · · Investor relations

Briefing

Praxis Precision Medicines reported financial results for the first quarter ended March 31, 2021.

Praxis Precision Medicines reported a net loss of $27.4 million for the first quarter of 2021. As of March 31, 2021, Praxis had $270.8 million in cash, cash equivalents and marketable securities.

  • Expanded pipeline with new indications for PRAX-114 and PRAX-944
  • PRAX-114 Phase 2 trial for treatment of post-traumatic stress disorder to initiate in 2H21
  • PRAX-114 Phase 2 trial for treatment of essential tremor to initiate in 2H21
  • PRAX-944 Phase 2 trial for treatment of Parkinson’s disease to initiate in 1H22

Headline financials

EPS (adj)

-$10.65

Previous: -$76.69+86.1%
Capital Expenditures

$4K

No prior period
Free Cash Flow

-$25.7M

No prior period
Net Income

-$27.4M

Previous: -$8.33M-228.6%
Operating Income

-$27.4M

Previous: -$8.47M-223.8%
Cash & Equivalents

$131M

No prior period
Total Assets

$279M

No prior period
Stock-Based Comp

$4.67M

No prior period

Revenue & EPS history

Praxis · Revenue · Quarterly

$0

Q1 2026
Beat estimate in 1 of 2 quarters(50%)
ActualEstimate

Revenue by segment

Praxis · $500K total across 1 segment · Q3 2023

  • Collaboration Revenue
    $500K

Forward guidance

Praxis plans to initiate multiple Phase 2 trials in the second half of 2021 and the first half of 2022.

Tailwinds

  • Initiate PRAX-114 Phase 2 trial for PTSD in 2H21
  • Initiate PRAX-114 Phase 2 trial for essential tremor in 2H21
  • Initiate PRAX-944 Phase 2 trial for Parkinson’s disease in 1H22
  • Expect topline results from PRAX-114 Phase 2/3 Aria Study for MDD in 1H22
  • Initiate PRAX-114 Phase 2 Study for adjunctive treatment of MDD in 3Q21

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2021

Historical avgQ1 2021

-0.3%

Avg return

Earnings day

+3.3%

Avg return

5 days after

-4.0%

Avg return

30 days after

57%

13 / 23 earnings

Positive

+22.3%

Q2 2022

Best reaction

-40.6%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.7%-6.4%-22.2%
Q4 2025+0.5%+4.2%-9.3%
Q3 2025-4.7%-2.2%+44.4%
Q1 2025+0.2%-3.5%+16.3%
Q4 2024-40.6%-41.8%-40.6%
Q3 2024+3.6%+16.6%-4.0%
Q2 2024-1.1%+2.0%+13.3%
Q1 2024-5.9%-6.9%-15.8%
Q4 2023+6.3%+2.3%-7.3%
Q3 2023+1.4%-0.6%+21.6%
Q2 2023+10.8%+17.0%+43.9%
Q1 2023-2.8%-1.9%-7.7%
Q4 2022-4.2%-13.0%-77.0%
Q3 2022-12.5%-11.2%-13.3%
Q2 2022+22.3%+33.2%-3.4%
Q1 2022+14.0%+28.1%-77.7%
Q4 2021-1.9%-4.2%-22.9%
Q3 2021+2.4%+2.0%-17.1%
Q2 2020+12.7%+35.9%+42.8%
Q2 2021+12.7%+35.9%+42.8%
Q1 2021-16.4%-16.1%-20.2%
Q4 2020-6.8%-11.5%-34.0%
Q3 2020+2.3%+18.2%+54.7%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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