NASDAQ$PRAX

Praxis Precision Medicines I · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

Praxis Precision Medicines reported Q2 2026 financial results with increased operating expenses and a larger net loss.

The company reported a net loss of $83.7 million for the quarter, driven by higher research and development and general and administrative expenses. Cash and cash equivalents stood at $474.8 million with total assets of $1.39 billion. No revenue was recorded as the company remains in the development stage.

  • Net loss widened to $83.7 million from $71.1 million in the prior-year quarter.
  • R&D expenses rose to $69.4 million while G&A expenses increased to $27.5 million.
  • Cash position strengthened to $474.8 million following a follow-on offering.
  • Multiple product candidates advanced with NDA submissions accepted for review.

Headline financials

Total Revenue

$0.00

Previous: $357K-100.0%
EPS (adj)

-$2.87

Previous: -$1.74-64.9%
Research and development expenses

$69.4M

No prior period
General and administrative expenses

$27.5M

No prior period
Stock-based compensation expense

$11.3M

No prior period
Capital Expenditures

-$56K

No prior period
Net Income

-$71.1M

Previous: -$32.7M-117.7%
Operating Income

-$76.1M

Previous: -$37.5M-102.9%
Cash & Equivalents

$475M

No prior period
Total Assets

$1.39B

No prior period

Revenue & EPS history

Praxis · Revenue · Quarterly

$0

Q2 2025-100%vs Q2 2024
Beat estimate in 2 of 8 quarters(25%)
ActualEstimate

Revenue by segment

Praxis · $500K total across 1 segment · Q3 2023

  • Collaboration Revenue
    $500K

Forward guidance

The company continues to advance multiple late-stage programs with regulatory submissions under review and ongoing commercial preparations.

Tailwinds

  • NDA for ulixacaltamide accepted with PDUFA date of January 29, 2027
  • NDA for relutrigine accepted with updated PDUFA date of December 27, 2026
  • BIMO inspection completed successfully with no Form 483 issued

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports

Historical avg

-0.3%

Avg return

Earnings day

+3.3%

Avg return

5 days after

-4.0%

Avg return

30 days after

57%

13 / 23 earnings

Positive

+22.3%

Q2 2022

Best reaction

-40.6%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026+1.7%-6.4%-22.2%
Q4 2025+0.5%+4.2%-9.3%
Q3 2025-4.7%-2.2%+44.4%
Q1 2025+0.2%-3.5%+16.3%
Q4 2024-40.6%-41.8%-40.6%
Q3 2024+3.6%+16.6%-4.0%
Q2 2024-1.1%+2.0%+13.3%
Q1 2024-5.9%-6.9%-15.8%
Q4 2023+6.3%+2.3%-7.3%
Q3 2023+1.4%-0.6%+21.6%
Q2 2023+10.8%+17.0%+43.9%
Q1 2023-2.8%-1.9%-7.7%
Q4 2022-4.2%-13.0%-77.0%
Q3 2022-12.5%-11.2%-13.3%
Q2 2022+22.3%+33.2%-3.4%
Q1 2022+14.0%+28.1%-77.7%
Q4 2021-1.9%-4.2%-22.9%
Q3 2021+2.4%+2.0%-17.1%
Q2 2020+12.7%+35.9%+42.8%
Q2 2021+12.7%+35.9%+42.8%
Q1 2021-16.4%-16.1%-20.2%
Q4 2020-6.8%-11.5%-34.0%
Q3 2020+2.3%+18.2%+54.7%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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