NASDAQ$OKUR

OnKure Therapeutics Inc · Q4 2024 earnings

Q4 2024 earnings · · Investor relations

Briefing

OnKure Therapeutics reported Q4 2024 a net loss of $17.4M, diluted EPS of $-1.37.

For Q4 2024, OnKure Therapeutics reported net loss was $17.4M, diluted EPS was $-1.37. Management discusses segment trends, liquidity, and outlook in the quarterly filing.

  • Net loss $17.4M.
  • Diluted EPS $-1.37.
  • MD&A highlights operating priorities, liquidity, and sector risks.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$1.37

Previous: -$0.71-93.0%
R&D Expenses

$14.4M

No prior period
G&A Expenses

$4.34M

No prior period
Total Operating Expenses

$18.7M

No prior period
Net Loss

-$17.4M

No prior period
Weighted Avg Shares

12.8M

No prior period
Capital Expenditures

-$50K

Previous: -$25K-100.0%
Net Income

-$17.4M

Previous: -$23.6M+26.3%
Operating Income

-$18.7M

Previous: -$25M+25.2%
Gross Profit

-$419K

Previous: $0.00
R&D Expense

$36.9M

Previous: $17.6M+109.9%

Revenue & EPS history

Reneo Pharmaceuticals · Revenue · Quarterly

$0

Q4 2024
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Outlook emphasizes clinical milestones, liquidity runway, and operating expense discipline.

Tailwinds

  • Pipeline progress and partnership economics.
  • Cash supports near-term operating plans.

Headwinds

  • Operating losses until commercial scale.
  • Financing and trial outcomes affect funding costs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+2.2%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.6%

Avg return

30 days after

52%

11 / 21 earnings

Positive

+21.2%

Q2 2025

Best reaction

-10.3%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-1.7%-15.0%-6.3%
Q3 2025-5.5%-2.5%-3.2%
Q2 2025+21.2%+24.6%+20.2%
Q1 2025+12.5%+7.5%+21.0%
Q4 2024+3.7%+4.8%-40.0%
Q3 2024+3.2%+1.8%-16.7%
Q2 2024+9.7%+15.7%+5.2%
Q1 2024+2.4%+3.0%+0.6%
Q4 2023+3.0%+3.6%+1.2%
Q3 2023-0.9%+5.6%+21.1%
Q2 2023-6.3%-15.1%+7.1%
Q1 2023-1.4%-0.9%+79.3%
Q4 2022-10.3%-1.0%+65.1%
Q3 2022-3.0%-8.6%-35.4%
Q2 2022-3.0%+4.1%+34.6%
Q1 2022-5.9%-10.8%-28.2%
Q4 2021-1.4%-6.8%-34.7%
Q3 2021+14.8%+5.7%-13.2%
Q2 2021+0.1%-3.2%+2.0%
Q4 2020+7.5%+2.9%-2.3%
Q1 2021+7.5%+2.9%-2.3%

Discussion

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