NASDAQ$OKUR

OnKure Therapeutics Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Reported financial results for the quarter ended September 30, 2022.

Reneo Pharmaceuticals reported a net loss of $13.0 million, or $0.53 per share, for the three months ended September 30, 2022. The company had approximately $116 million in cash, cash equivalents and short-term investments as of September 30, 2022. They have achieved over 80% enrollment in the ongoing pivotal STRIDE study in primary mitochondrial myopathy (PMM) patients with mitochondrial DNA (mtDNA) defects and remain on track to announce topline data from this study in the fourth quarter of 2023.

  • Enrolled over 80% of the population in the ongoing pivotal STRIDE study
  • Positive data from the STRIDE and STRIDE AHEAD studies could potentially support registration of REN001 for PMM patients with mtDNA defects
  • Announced plans to study REN001 in PMM patients with nDNA defects
  • Announced successful Phase 1b study in LC-FAOD patients with nDNA defects, and plans to move the program forward into Phase 2 development

Headline financials

EPS (adj)

-$0.53

Previous: -$0.42-26.2%
Capital Expenditures

$28K

Previous: $77K-63.6%
Free Cash Flow

-$10.8M

Previous: -$9.75M-11.0%
Net Income

-$13M

Previous: -$12.7M-2.4%
Operating Income

-$13.8M

Previous: -$12.8M-8.5%
Cash & Equivalents

$62.1M

Previous: $126M-50.8%
Total Assets

$123M

Previous: $163M-24.8%
Stock-Based Comp

$990K

Previous: $1.15M-13.5%

Revenue & EPS history

Reneo Pharmaceuticals · Revenue · Quarterly

$458K

Q1 2026
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Completion of enrollment in the pivotal STRIDE study in the first quarter of 2023; topline data in the fourth quarter of 2023. Meetings with regulatory agencies to discuss a Phase 2 study for LC-FAOD patients in the fourth quarter of 2022; update to be provided in the first quarter of 2023. Update on plans to study REN001 in PMM patients with nDNA defects in the first quarter of 2023

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

+2.2%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.6%

Avg return

30 days after

52%

11 / 21 earnings

Positive

+21.2%

Q2 2025

Best reaction

-10.3%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-1.7%-15.0%-6.3%
Q3 2025-5.5%-2.5%-3.2%
Q2 2025+21.2%+24.6%+20.2%
Q1 2025+12.5%+7.5%+21.0%
Q4 2024+3.7%+4.8%-40.0%
Q3 2024+3.2%+1.8%-16.7%
Q2 2024+9.7%+15.7%+5.2%
Q1 2024+2.4%+3.0%+0.6%
Q4 2023+3.0%+3.6%+1.2%
Q3 2023-0.9%+5.6%+21.1%
Q2 2023-6.3%-15.1%+7.1%
Q1 2023-1.4%-0.9%+79.3%
Q4 2022-10.3%-1.0%+65.1%
Q3 2022-3.0%-8.6%-35.4%
Q2 2022-3.0%+4.1%+34.6%
Q1 2022-5.9%-10.8%-28.2%
Q4 2021-1.4%-6.8%-34.7%
Q3 2021+14.8%+5.7%-13.2%
Q2 2021+0.1%-3.2%+2.0%
Q4 2020+7.5%+2.9%-2.3%
Q1 2021+7.5%+2.9%-2.3%

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