NASDAQ$OKUR

OnKure Therapeutics Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Reneo Pharmaceuticals reported a net loss for the third quarter of 2021 and provided an update on its clinical programs.

Reneo Pharmaceuticals reported a net loss of $12.7 million, or $0.52 per share, for the three months ended September 30, 2021. The company's cash, cash equivalents and short-term investments totaled $157.7 million as of September 30, 2021.

  • Initiated enrollment of STRIDE, a global, double-blind, randomized, placebo-controlled Phase 2b trial of REN001 in patients with PMM
  • Completed enrollment in REN001-102, an open-label Phase 1b clinical trial in patients with LC-FAOD
  • Appointed Ashley Hall as Chief Development Officer to lead nonclinical and clinical operations, global regulatory affairs, pharmaceutical development, and program management
  • Received a notice of allowance from the USPTO for a composition of matter patent application covering the REN001 drug substance

Headline financials

EPS (adj)

-$0.42

No prior period
R&D Expenses

$9.32M

No prior period
G&A Expenses

$3.43M

No prior period
Capital Expenditures

$77K

No prior period
Free Cash Flow

-$9.75M

No prior period
Net Income

-$12.7M

No prior period
Operating Income

-$12.8M

No prior period
Cash & Equivalents

$126M

No prior period
Total Assets

$163M

No prior period
Stock-Based Comp

$1.15M

No prior period

Revenue & EPS history

Reneo Pharmaceuticals · Revenue · Quarterly

$458K

Q1 2026

Forward guidance

Anticipated Upcoming Milestones include results of the Phase 1b clinical trial of REN001 in McArdle disease (1Q 2022), results of the Phase 1b clinical trial of REN001 in LC-FAOD (2Q 2022), and results of the FORWARD natural history study in LC-FAOD (2Q 2022).

Tailwinds

  • Results of the Phase 1b clinical trial of REN001 in McArdle disease (1Q 2022)
  • Results of the Phase 1b clinical trial of REN001 in LC-FAOD (2Q 2022)
  • Results of the FORWARD natural history study in LC-FAOD (2Q 2022)
  • Credit Suisse 30th Annual Healthcare Conference, November 8 - 11, 2021
  • Jefferies 12th Annual London Healthcare Conference, November 16 – 19, 2021

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

+2.2%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.6%

Avg return

30 days after

52%

11 / 21 earnings

Positive

+21.2%

Q2 2025

Best reaction

-10.3%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-1.7%-15.0%-6.3%
Q3 2025-5.5%-2.5%-3.2%
Q2 2025+21.2%+24.6%+20.2%
Q1 2025+12.5%+7.5%+21.0%
Q4 2024+3.7%+4.8%-40.0%
Q3 2024+3.2%+1.8%-16.7%
Q2 2024+9.7%+15.7%+5.2%
Q1 2024+2.4%+3.0%+0.6%
Q4 2023+3.0%+3.6%+1.2%
Q3 2023-0.9%+5.6%+21.1%
Q2 2023-6.3%-15.1%+7.1%
Q1 2023-1.4%-0.9%+79.3%
Q4 2022-10.3%-1.0%+65.1%
Q3 2022-3.0%-8.6%-35.4%
Q2 2022-3.0%+4.1%+34.6%
Q1 2022-5.9%-10.8%-28.2%
Q4 2021-1.4%-6.8%-34.7%
Q3 2021+14.8%+5.7%-13.2%
Q2 2021+0.1%-3.2%+2.0%
Q4 2020+7.5%+2.9%-2.3%
Q1 2021+7.5%+2.9%-2.3%

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