NASDAQ$OKUR
OnKure Therapeutics Inc · Q1 2026 earnings
Q1 2026 earnings · · Investor relations
Briefing
OnKure Therapeutics reported Q1 2026 net loss of $15.2M with no product revenue.
The clinical-stage biotech reported a net loss of $15.2 million for the three months ended March 31, 2026, compared with a larger loss in the prior year period. The company has no product revenue and funds operations through equity and collaboration sources.
- Net loss $(15.2)M; pre-revenue stage.
- R&D spend on precision oncology programs.
- Accumulated deficit $(229.4)M at quarter end.
- Cash runway discussed in liquidity section.
Headline financials
Revenue & EPS history
Reneo Pharmaceuticals · Revenue · Quarterly
$458K
Forward guidance
MD&A focuses on clinical trial enrollment, partnership optionality, and financing needs.
Tailwinds
- Loss narrower than full-year 2025 quarterly run-rate implied.
- Pipeline targeting MAPK pathway tumors.
Headwinds
- No revenue until regulatory approvals.
- Clinical and financing dilution risk.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2026
+2.2%
Avg return
Earnings day
+0.9%
Avg return
5 days after
+3.6%
Avg return
30 days after
52%
11 / 21 earnings
Positive
+21.2%
Q2 2025
Best reaction
-10.3%
Q4 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -1.7% | -15.0% | -6.3% | |
| Q3 2025 | -5.5% | -2.5% | -3.2% | |
| Q2 2025 | +21.2% | +24.6% | +20.2% | |
| Q1 2025 | +12.5% | +7.5% | +21.0% | |
| Q4 2024 | +3.7% | +4.8% | -40.0% | |
| Q3 2024 | +3.2% | +1.8% | -16.7% | |
| Q2 2024 | +9.7% | +15.7% | +5.2% | |
| Q1 2024 | +2.4% | +3.0% | +0.6% | |
| Q4 2023 | +3.0% | +3.6% | +1.2% | |
| Q3 2023 | -0.9% | +5.6% | +21.1% | |
| Q2 2023 | -6.3% | -15.1% | +7.1% | |
| Q1 2023 | -1.4% | -0.9% | +79.3% | |
| Q4 2022 | -10.3% | -1.0% | +65.1% | |
| Q3 2022 | -3.0% | -8.6% | -35.4% | |
| Q2 2022 | -3.0% | +4.1% | +34.6% | |
| Q1 2022 | -5.9% | -10.8% | -28.2% | |
| Q4 2021 | -1.4% | -6.8% | -34.7% | |
| Q3 2021 | +14.8% | +5.7% | -13.2% | |
| Q2 2021 | +0.1% | -3.2% | +2.0% | |
| Q4 2020 | +7.5% | +2.9% | -2.3% | |
| Q1 2021 | +7.5% | +2.9% | -2.3% |
Discussion
Share your read of this quarter. Sign-in carries your eToro identity.
Join the conversation
Sign in with eToro to post your read of this quarter and vote on others'.
Sign in with eToro