NASDAQ$MIST

Milestone Pharmaceuticals Inc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Milestone Pharmaceuticals reported financial results for the second quarter ended June 30, 2022, and provided a clinical and corporate update.

Milestone Pharmaceuticals reported on their Phase 3 PSVT clinical program, highlighting the crossing of the 180th event in the RAPID trial. They are focusing on data cleaning and analysis and anticipate reporting top line data in the middle of the second half of the year. A Phase 3 PSVT study was initiated in China.

  • Phase 3 RAPID study reached the target of 180 confirmed PSVT events treated with double-blind study medication required to initiate primary efficacy analysis.
  • Topline data readout for RAPID study remains on track for mid-second half 2022.
  • Phase 3 PSVT study initiated in China
  • Etripamil is in Phase 3 clinical-stage program for the treatment of paroxysmal supraventricular tachycardia (PSVT) and in a Phase 2 proof-of-concept trial for the treatment of patients with atrial fibrillation with rapid ventricular rate (AFib-RVR).

Headline financials

EPS (adj)

-$0.39

Previous: $0.02-2050.0%
Capital Expenditures

$59K

No prior period
Free Cash Flow

-$14.1M

No prior period
Net Income

-$16.5M

Previous: $770K-2241.6%
Operating Income

-$16.8M

Previous: $712K-2460.4%
Cash & Equivalents

$63.2M

Previous: $97.8M-35.3%
Total Assets

$91.3M

Previous: $145M-37.2%
Stock-Based Comp

$2.41M

Previous: $1.91M+26.1%

Revenue & EPS history

Milestone Pharmaceuticals · Revenue · Quarterly

$238K

Q1 2026
Beat estimate in 1 of 3 quarters(33%)
ActualEstimate

Forward guidance

This press release contains forward-looking statements regarding the potential of etripamil, the design, progress, timing, scope and results of the RAPID and ReVeRA trials, Milestone’s ability to execute on the remainder of the PSVT program, the timing of release of unblind RAPID results and topline data, Milestone’s ongoing plans to study etripamil in atrial fibrillation patients, the sufficiency of Milestone’s current cash resources, and estimates about the addressable market and commercial potential for treatments of atrial fibrillation with rapid ventricular rate.

Tailwinds

  • Potential of etripamil to serve as a promising therapy for PSVT patients
  • Design, progress, timing, scope and results of the RAPID and ReVeRA trials
  • Milestone’s ability to execute on the remainder of the PSVT program
  • Timing of release of unblind RAPID results and topline data
  • Milestone’s ongoing plans to study etripamil in atrial fibrillation patients

Headwinds

  • Risks inherent in biopharmaceutical product development and clinical trials, including the lengthy and uncertain regulatory approval process
  • Uncertainties related to the timing of initiation, enrollment, completion and evaluation of clinical trials
  • Risks and uncertainty related to the complexity inherent in cleaning, verifying and analyzing trial data
  • Whether the clinical trials will validate the safety and efficacy of etripamil for PSVT or other indications
  • Risks related to pandemics and public health emergencies, including those related to the ongoing COVID-19 pandemic, and risks related the sufficiency of Milestone’s capital resources and its ability to raise additional capital.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

+1.7%

Avg return

Earnings day

-0.2%

Avg return

5 days after

+2.2%

Avg return

30 days after

64%

18 / 28 earnings

Positive

+24.1%

Q3 2021

Best reaction

-23.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-9.5%-23.2%
Q4 2026-20.0%-26.5%+23.5%
Q3 2025+1.0%+21.5%+26.2%
Q2 2025+7.1%+9.7%+23.2%
Q1 2025-1.7%+8.4%+38.7%
Q4 2024+7.9%-53.7%-38.9%
Q3 2024-5.2%-12.4%-4.1%
Q1 2024+1.2%+2.4%-16.5%
Q4 2023+16.0%+20.7%+9.3%
Q3 2023-23.0%-24.4%-13.7%
Q2 2023+1.6%+2.6%-7.1%
Q1 2023+12.8%+0.5%+1.3%
Q4 2022-4.0%-0.3%-9.0%
Q3 2022+13.0%+7.1%-0.7%
Q2 2022+3.6%+5.3%+29.2%
Q1 2022-2.5%+1.6%+1.6%
Q4 2021+12.4%+17.5%+22.0%
Q3 2021+24.1%+13.9%+4.5%
Q2 2021+0.2%+2.1%+7.1%
Q1 2021+0.5%+1.3%+6.1%
Q4 2020-6.6%-2.4%-4.0%
Q3 2020+6.1%+6.0%+19.8%
Q2 2020-1.8%+0.3%-12.2%
Q1 2020+0.3%+4.8%+29.5%
Q4 2019+7.4%+8.7%-90.4%
Q3 2019-4.2%-1.2%-7.2%
Q2 2019+7.8%+9.9%+38.1%
Q1 2019+3.4%-4.5%-16.2%
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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