NASDAQ$MIST

Milestone Pharmaceuticals Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Milestone reported Q1 2026 CARDAMYST product revenue of $0.2M with a net loss of $26.1M.

For the quarter ended March 31, 2026, Milestone recognized U.S. CARDAMYST (etripamil) product revenue of $0.2 million following December 2025 FDA approval for PSVT (no revenue in Q1 2025). Net loss was $26.1 million versus $20.8 million a year ago. Cash used in operations was $16.1 million.

  • Initial CARDAMYST sales $0.2M in first commercial quarter.
  • Net loss $26.1M as launch and R&D spend continue.
  • FDA approval of etripamil in Dec 2025 enables U.S. sales.
  • Operating cash use $16.1M.

Headline financials

Total Revenue

$238K

Previous: $0.00
EPS (adj)

-$0.20

Previous: -$0.31+35.5%
Capital Expenditures

-$45K

Previous: -$6K-650.0%
Free Cash Flow

-$16.1M

Previous: -$14M-15.3%
Net Income

-$26.1M

Previous: -$20.8M-25.6%
Operating Income

-$23.7M

Previous: -$20.6M-14.8%
Gross Profit

$224K

Previous: -$27K+929.6%
Cash & Equivalents

$71.3M

No prior period
Total Assets

$194M

No prior period

Revenue & EPS history

Milestone Pharmaceuticals · Revenue · Quarterly

$238K

Q1 2026
Beat estimate in 2 of 3 quarters(67%)
ActualEstimate

Forward guidance

Early launch phase without quantitative annual revenue guidance in the 10-Q.

Tailwinds

  • Commercial channel opened in U.S. for PSVT.
  • Experience from EU launch informs U.S. rollout.

Headwinds

  • Revenue immaterial versus expense base.
  • Losses expected to continue during launch ramp.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+2.5%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+1.5%

Avg return

30 days after

67%

18 / 27 earnings

Positive

+24.1%

Q3 2021

Best reaction

-23.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026
Q1 2026-9.5%-23.2%
Q3 2025+1.0%+21.5%+26.2%
Q2 2025+7.1%+9.7%+23.2%
Q1 2025-1.7%+8.4%+38.7%
Q4 2024+7.9%-53.7%-38.9%
Q3 2024-5.2%-12.4%-4.1%
Q1 2024+1.2%+2.4%-16.5%
Q4 2023+16.0%+20.7%+9.3%
Q3 2023-23.0%-24.4%-13.7%
Q2 2023+1.6%+2.6%-7.1%
Q1 2023+12.8%+0.5%+1.3%
Q4 2022-4.0%-0.3%-9.0%
Q3 2022+13.0%+7.1%-0.7%
Q2 2022+3.6%+5.3%+29.2%
Q1 2022-2.5%+1.6%+1.6%
Q4 2021+12.4%+17.5%+22.0%
Q3 2021+24.1%+13.9%+4.5%
Q2 2021+0.2%+2.1%+7.1%
Q1 2021+0.5%+2.9%+8.1%
Q4 2020-6.6%-2.4%-4.2%
Q3 2020+6.1%+6.0%+19.8%
Q2 2020-1.8%+0.3%-12.2%
Q1 2020+0.3%+4.8%+29.5%
Q4 2019+7.4%+8.7%-90.4%
Q3 2019-4.2%-1.2%-7.2%
Q2 2019+7.8%+9.9%+38.1%
Q1 2019+3.4%-4.5%-16.2%
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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