NASDAQ$MIST

Milestone Pharmaceuticals Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Milestone Pharmaceuticals reported financial results for the first quarter ended March 31, 2023, and provided a clinical and corporate update.

Milestone Pharmaceuticals is on track for NDA submission for etripamil in Q3 2023. They are expanding market preparation activities and assessing etripamil's potential in AFib-RVR patients, with Phase 2 ReVeRA topline data expected in 2H 2023. Cash resources are expected to fund operations into mid-2025.

  • NDA submission for etripamil in patients with PSVT is currently on track for 3Q23.
  • Company to host virtual KOL event focused on etripamil for the potential treatment of AFib-RVR on Monday, May 22, 2023.
  • Topline data from Phase 2 ReVeRA study evaluating etripamil in patients with AFib-RVR expected in 2H, 2023.
  • Cash resources as of March 31, 2023, together with strategic March 2023 financing, are expected to fund operations into mid-2025.

Headline financials

Total Revenue

$1M

No prior period
EPS (adj)

-$0.35

Previous: -$0.33-6.1%
Capital Expenditures

$32K

No prior period
Free Cash Flow

-$13.9M

No prior period
Net Income

-$14.4M

Previous: -$14M-3.1%
Operating Income

-$15.5M

Previous: -$14M-10.4%
Cash & Equivalents

$74M

Previous: $92.2M-19.8%
Total Assets

$111M

Previous: $106M+5.0%
Stock-Based Comp

$2.29M

Previous: $2.11M+8.5%

Revenue & EPS history

Milestone Pharmaceuticals · Revenue · Quarterly

$1M

Q1 2023
Beat estimate in 1 of 3 quarters(33%)
ActualEstimate

Forward guidance

Milestone Pharmaceuticals is focused on the development and commercialization of innovative cardiovascular medicines. The company's lead product candidate, etripamil, has completed Phase 3 trials for PSVT and is in a Phase 2 trial for AFib-RVR. Milestone expects to submit an NDA for etripamil in Q3 2023 and anticipates topline data from the Phase 2 ReVeRA study in 2H 2023.

Tailwinds

  • Potential of etripamil to serve as a promising therapy for PSVT patients.
  • Timing of the NDA submission for etripamil nasal spray.
  • Potential for clinical trial data from the Phase 2 ReVeRA program later this year.
  • Ability to fund operations into the middle of 2025.

Headwinds

  • Risks inherent in biopharmaceutical product development and clinical trials, including the lengthy and uncertain regulatory approval process.
  • Uncertainties related to the timing of initiation, enrollment, completion, evaluation and results of our clinical trials.
  • Risks and uncertainty related to the complexity inherent in cleaning, verifying and analyzing trial data.
  • Whether the clinical trials will validate the safety and efficacy of etripamil for PSVT or other indications.
  • Sufficiency of Milestone's capital resources and its ability to raise additional capital in the current economic climate.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+1.7%

Avg return

Earnings day

-0.2%

Avg return

5 days after

+2.2%

Avg return

30 days after

64%

18 / 28 earnings

Positive

+24.1%

Q3 2021

Best reaction

-23.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-9.5%-23.2%
Q4 2026-20.0%-26.5%+23.5%
Q3 2025+1.0%+21.5%+26.2%
Q2 2025+7.1%+9.7%+23.2%
Q1 2025-1.7%+8.4%+38.7%
Q4 2024+7.9%-53.7%-38.9%
Q3 2024-5.2%-12.4%-4.1%
Q1 2024+1.2%+2.4%-16.5%
Q4 2023+16.0%+20.7%+9.3%
Q3 2023-23.0%-24.4%-13.7%
Q2 2023+1.6%+2.6%-7.1%
Q1 2023+12.8%+0.5%+1.3%
Q4 2022-4.0%-0.3%-9.0%
Q3 2022+13.0%+7.1%-0.7%
Q2 2022+3.6%+5.3%+29.2%
Q1 2022-2.5%+1.6%+1.6%
Q4 2021+12.4%+17.5%+22.0%
Q3 2021+24.1%+13.9%+4.5%
Q2 2021+0.2%+2.1%+7.1%
Q1 2021+0.5%+1.3%+6.1%
Q4 2020-6.6%-2.4%-4.0%
Q3 2020+6.1%+6.0%+19.8%
Q2 2020-1.8%+0.3%-12.2%
Q1 2020+0.3%+4.8%+29.5%
Q4 2019+7.4%+8.7%-90.4%
Q3 2019-4.2%-1.2%-7.2%
Q2 2019+7.8%+9.9%+38.1%
Q1 2019+3.4%-4.5%-16.2%
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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