NASDAQ$MDGL

Madrigal Pharmaceuticals Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Madrigal's financial position remained strong, and the company continued to advance its Phase 3 clinical program for resmetirom.

Madrigal Pharmaceuticals reported its third quarter 2021 financial results and provided a corporate update, highlighting the progress of its MAESTRO-NASH and MAESTRO-NAFLD-1 studies and the presentation of data at The Liver Meeting® 2021.

  • Madrigal is on track to complete the double-blind portion of the Phase 3 MAESTRO-NAFLD-1 study and report topline data by year-end.
  • Additional data from the open-label portion of the MAESTRO-NAFLD-1 study will be presented at AASLD's The Liver Meeting®.
  • Madrigal announced an alliance with the Fatty Liver Foundation to support the NAFLD Screening Fund.
  • Stephen Dodge and Kia Motesharei have joined Madrigal as Senior Vice President and Global Head of Medical Affairs and Senior Vice President Business & Corporate Development, respectively.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$3.79

Previous: -$3.75-1.1%
R&D Expense

$54.9M

Previous: $53.3M+3.0%
SG&A Expense

$8.29M

Previous: $5.5M+50.7%
Capital Expenditures

-$96K

Previous: -$324K+70.4%
Free Cash Flow

-$63.2M

Previous: -$58.3M-8.4%
Net Income

-$63.1M

Previous: -$58M-8.9%
Operating Income

-$63.2M

Previous: -$58.8M-7.4%
Gross Profit

$0.00

Previous: $0.00
Cash & Equivalents

$299M

Previous: $336M-11.0%
Total Assets

$305M

No prior period
Stock-Based Comp

$6.24M

No prior period

Revenue & EPS history

Madrigal · Revenue · Quarterly

$0

Q3 2021
Beat estimate in 0 of 5 quarters(0%)
ActualEstimate

Forward guidance

Madrigal anticipates topline data from the double-blind portion of its Phase 3 MAESTRO-NAFLD-1 study by year-end 2021, with additional data rollout in early 2022.

Tailwinds

  • On track to complete the double-blind portion of MAESTRO-NAFLD-1.
  • Topline data from MAESTRO-NAFLD-1 expected by year-end.
  • Additional data rollout from MAESTRO-NAFLD-1 in early 2022.
  • Advancing MAESTRO-NASH, the pivotal serial liver biopsy study.
  • Presenting additional data from the open-label portion of MAESTRO-NAFLD-1 at AASLD.

Headwinds

  • Clinical development of resmetirom is subject to risks and uncertainties.
  • Enrollment uncertainties may arise, particularly in relation to COVID-19-related measures.
  • Outcomes or trends from competitive studies could impact results.
  • Future topline data timing or results are uncertain.
  • Achieving potential benefits in studies with substantially more patients than prior studies carries risks.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

-0.6%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+7.8%

Avg return

30 days after

45%

29 / 65 earnings

Positive

+48.0%

Q3 2024

Best reaction

-23.3%

Q4 2015

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.0%-1.2%-3.2%
Q4 2025-11.1%-10.5%-10.2%
Q3 2025+7.8%+18.7%+42.2%
Q1 2025-1.9%-11.6%-17.6%
Q4 2024+15.0%+1.3%+5.9%
Q3 2024+48.0%+56.4%+52.0%
Q2 2024-8.6%-9.2%-8.5%
Q1 2024-11.7%-12.9%+2.5%
Q4 2023-1.5%+2.8%+11.4%
Q3 2023+3.6%-5.5%+61.1%
Q2 2023-6.0%-4.5%+6.4%
Q1 2023-5.4%-5.2%-12.8%
Q4 2022-5.4%-7.1%-19.6%
Q3 2022-6.7%-10.1%+12.8%
Q2 2022+22.8%+12.1%+10.8%
Q1 2022-0.2%+1.8%+15.0%
Q4 2021+7.9%+13.1%+9.2%
Q3 2021-0.5%-1.6%-16.6%
Q2 2021+7.5%+0.8%-4.5%
Q1 2021+0.7%+2.3%-22.0%
Q4 2020-1.3%-6.9%-5.3%
Q3 2020-6.8%-2.2%-10.9%
Q2 2020-1.1%-2.2%+2.3%
Q1 2020+2.9%+25.1%+27.6%
Q4 2019-2.5%+2.6%-19.7%
Q3 2019+0.1%+7.9%+22.1%
Q2 2019+2.0%+2.0%+9.8%
Q1 2019+0.2%-3.4%-8.0%
Q4 2018-2.4%+3.1%-6.9%
Q3 2018+5.2%-7.8%-39.7%
Q2 2018-1.0%-5.9%-11.0%
Q1 2018-0.0%+2.2%+138.3%
Q4 2017-16.4%-20.4%-15.8%
Q3 2017-0.2%-5.7%+84.7%
Q2 2017-0.8%+1.7%+13.5%
Q1 2017+2.1%+4.5%-0.3%
Q4 2016-2.2%-4.9%+6.8%
Q3 2016+5.3%+2.4%-1.4%
Q2 2016+3.8%+11.5%+1.9%
Q1 2016+10.5%
Q4 2015-23.3%
Q3 2015+0.0%
Q2 2015-3.4%
Q1 2015+1.3%
Q4 2014-6.1%
Q3 2014+10.6%
Q2 2014+0.5%
Q1 2014+3.3%
Q4 2013-10.1%
Q3 2013+0.9%
Q2 2013-4.2%
Q1 2013+2.5%
Q4 2012-5.0%
Q3 2012-5.2%
Q2 2012+0.3%
Q1 2012-11.2%
Q4 2011+0.2%
Q4 2009+0.2%
Q3 2011+4.4%
Q2 2011-10.1%
Q4 2010-10.1%
Q1 2011+1.6%
Q3 2010-6.1%
Q2 2010-5.6%
Q1 2010-16.5%

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