NASDAQ$LYEL
Lyell Immunopharma Inc · Q3 2024 earnings
Q3 2024 earnings · · Investor relations
Briefing
Lyell Immunopharma reported third quarter 2024 financial results and business highlights.
Lyell Immunopharma reported a net loss of $44.6 million for the third quarter ended September 30, 2024, compared to a net loss of $50.9 million for the same period in 2023. The company's cash, cash equivalents and marketable securities totaled $460.7 million as of September 30, 2024, which is expected to fund operations into 2027. Lyell is advancing two wholly-owned product candidates: IMPT-314 is in Phase 1-2 clinical development and LYL119 is entering Phase 1 clinical development.
- Acquired ImmPACT Bio and strengthened clinical pipeline with the addition of IMPT-314, a dual-targeting CD19/CD20 CAR T-cell product candidate.
- Presenting initial data from Phase 1 multi-center clinical trial of IMPT-314 at the American Society of Hematology 2024 (ASH) Annual Meeting.
- Presenting three abstracts at the Society for Immunotherapy of Cancer (SITC) 2024 Annual Meeting highlighting anti-exhaustion technology and product candidates being advanced in Lyell’s pipeline.
- Cash, cash equivalents and marketable securities of $460.7 million as of September 30, 2024 funds the Company through multiple clinical milestones into 2027.
Headline financials
Revenue & EPS history
Lyell Immunopharma · Revenue · Quarterly
$34K
Forward guidance
Lyell anticipates benefits from the ImmPACT Bio acquisition, plans to accelerate IMPT-314 development, and expects its financial position to support pipeline advancement through multiple clinical milestones into 2027.
Tailwinds
- Anticipated benefits of Lyell’s acquisition of ImmPACT Bio
- Lyell’s ability to accelerate the development of IMPT-314 and deliver increased complete response rates
- Lyell’s initiation of a pivotal trial in 2025 for IMPT-314
- Lyell’s development plans for LYL119 and the effectiveness of any technologies incorporated into LYL119
- Lyell’s expectation that its financial position and cash runway will support advancement of its pipeline through multiple clinical milestones into 2027
Headwinds
- Inability to recognize the anticipated benefits of acquiring ImmPACT Bio and successful integration of ImmPACT Bio’s business with Lyell’s, including manufacturing IMPT-314 in Lyell’s LyFE manufacturing facility
- Effects of macroeconomic conditions, including any geopolitical instability and actual or perceived changes in interest rates and economic inflation
- Lyell’s ability to submit planned INDs or initiate or progress clinical trials on the anticipated timelines, if at all
- Lyell’s limited experience as a company in enrolling and conducting clinical trials, and lack of experience in completing clinical trials
- Lyell’s ability to manufacture and supply its product candidates for its clinical trials
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q3 2024
+1.5%
Avg return
Earnings day
-4.0%
Avg return
5 days after
+1.1%
Avg return
30 days after
73%
16 / 22 earnings
Positive
+20.3%
Q4 2024
Best reaction
-18.3%
Q3 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +1.1% | -7.0% | -42.1% | |
| Q4 2025 | +2.5% | -19.0% | -9.6% | |
| Q3 2025 | -1.3% | +1.7% | +95.5% | |
| Q1 2025 | +4.6% | +2.0% | +21.1% | |
| Q4 2024 | +20.3% | +15.5% | -10.3% | |
| Q3 2024 | -17.6% | -21.3% | -38.9% | |
| Q2 2024 | +1.4% | -8.1% | -20.9% | |
| Q1 2024 | +7.6% | +4.2% | +13.6% | |
| Q4 2023 | +2.5% | -8.6% | -21.8% | |
| Q3 2023 | +6.8% | -24.8% | -11.8% | |
| Q2 2023 | +1.5% | -1.9% | -16.8% | |
| Q1 2023 | +6.9% | +6.5% | +50.9% | |
| Q4 2022 | +9.6% | +1.4% | -1.8% | |
| Q3 2022 | -18.3% | -17.0% | -28.8% | |
| Q2 2022 | +16.3% | +20.2% | +10.1% | |
| Q1 2021 | -12.4% | -22.8% | +1.5% | |
| Q1 2022 | -12.4% | -22.8% | +1.5% | |
| Q4 2019 | +6.1% | +6.1% | +1.6% | |
| Q4 2021 | +6.1% | +6.1% | +1.6% | |
| Q3 2021 | -4.1% | -3.6% | -18.8% | |
| Q4 2020 | +2.8% | +2.2% | +24.6% | |
| Q2 2021 | +2.8% | +2.2% | +24.6% | |
| Q3 2020 | — | — | — | |
| Q2 2020 | — | — | — | |
| Q1 2020 | — | — | — |
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