NASDAQ$LYEL

Lyell Immunopharma Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Lyell Immunopharma reported financial results for the first quarter ended March 31, 2023.

Lyell Immunopharma reported a net loss of $67.0 million for the first quarter ended March 31, 2023. The company's cash, cash equivalents and marketable securities totaled $668.0 million as of March 31, 2023, which is expected to support operations into 2026.

  • Two phase 1 clinical trials are recruiting patients at 14 sites across the US.
  • Cash, cash equivalents and marketable securities totaled $668.0 million as of March 31, 2023, supporting pipeline advancement into 2026.
  • Net loss for the first quarter was $67.0 million, compared to $68.1 million for the same period in 2022.
  • Revenue was $0.1 million for the first quarter, compared to $0.6 million for the same period in 2022.

Headline financials

Total Revenue

$65K

Previous: $553K-88.2%
EPS (adj)

-$0.18

Previous: -$0.20+10.0%
Non-GAAP Net Loss

-$44.8M

Previous: -$50M+10.4%
Capital Expenditures

-$1.53M

Previous: -$9.73M+84.2%
Free Cash Flow

-$68.5M

Previous: -$77.9M+12.1%
Net Income

-$67M

Previous: -$68.1M+1.7%
Operating Income

-$62.6M

Previous: -$68.6M+8.8%
Gross Profit

$65K

Previous: $553K-88.2%
Cash & Equivalents

$668M

Previous: $223M+200.1%
Total Assets

$880M

Previous: $1.07B-17.9%
Stock-Based Comp

$13.9M

Previous: $22M-37.0%

Revenue & EPS history

Lyell Immunopharma · Revenue · Quarterly

$65K

Q1 2023-88.2%vs Q1 2022

Forward guidance

Lyell believes that its cash, cash equivalents and marketable securities balances will be sufficient to meet working capital and capital expenditure needs into 2026.

Tailwinds

  • Advancing four wholly-owned product candidates.
  • Two product candidates, LYL797 and LYL845, are in Phase 1 clinical development.
  • Two additional product candidates, LYL119 and a TIL product candidate incorporating novel genetic and epigenetic reprogramming technologies, are in preclinical development.
  • An IND for LYL119 is expected to be submitted in the first half of 2024.
  • Initial clinical data from the Phase 1 trial of LYL797 are expected in the first half of 2024.

Headwinds

  • Effects of geopolitical instability.
  • Macroeconomic conditions and the COVID-19 pandemic.
  • Lyell’s ability to submit planned INDs or initiate or progress clinical trials on the anticipated timelines, if at all.
  • Lyell’s limited experience as a company in enrolling and conducting clinical trials, and lack of experience in completing clinical trials.
  • Lyell’s ability to manufacture and supply its product candidates for its clinical trials.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+1.5%

Avg return

Earnings day

-4.0%

Avg return

5 days after

+1.1%

Avg return

30 days after

73%

16 / 22 earnings

Positive

+20.3%

Q4 2024

Best reaction

-18.3%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.1%-7.0%-42.1%
Q4 2025+2.5%-19.0%-9.6%
Q3 2025-1.3%+1.7%+95.5%
Q1 2025+4.6%+2.0%+21.1%
Q4 2024+20.3%+15.5%-10.3%
Q3 2024-17.6%-21.3%-38.9%
Q2 2024+1.4%-8.1%-20.9%
Q1 2024+7.6%+4.2%+13.6%
Q4 2023+2.5%-8.6%-21.8%
Q3 2023+6.8%-24.8%-11.8%
Q2 2023+1.5%-1.9%-16.8%
Q1 2023+6.9%+6.5%+50.9%
Q4 2022+9.6%+1.4%-1.8%
Q3 2022-18.3%-17.0%-28.8%
Q2 2022+16.3%+20.2%+10.1%
Q1 2021-12.4%-22.8%+1.5%
Q1 2022-12.4%-22.8%+1.5%
Q4 2019+6.1%+6.1%+1.6%
Q4 2021+6.1%+6.1%+1.6%
Q3 2021-4.1%-3.6%-18.8%
Q4 2020+2.8%+2.2%+24.6%
Q2 2021+2.8%+2.2%+24.6%
Q3 2020
Q2 2020
Q1 2020

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