NASDAQ$INSM
Insmed Incorporated · Q4 2024 earnings
Q4 2024 earnings · · Before market open · Investor relations
Briefing
Insmed reported a net loss increase while achieving strong revenue growth in Q4 2024.
Insmed reported total revenue of $104.4 million for Q4 2024, reflecting a 24.8% year-over-year increase. Net loss for the quarter was $235.5 million, widening from $186.1 million in Q4 2023. The company also reported an increase in operating expenses, primarily due to increased R&D and SG&A costs. Insmed ended the year with approximately $1.4 billion in cash, cash equivalents, and marketable securities.
- Q4 2024 revenue grew by 24.8% year-over-year to $104.4 million.
- Net loss widened to $235.5 million from $186.1 million in Q4 2023.
- R&D expenses increased to $179.7 million due to expanded clinical development.
- Company ended 2024 with $1.4 billion in cash and marketable securities.
Headline financials
Revenue & EPS history
Insmed · Revenue · Quarterly
$104M
Revenue by segment
Insmed · $73.3M total across 2 segments · Q2 2023
- ARIKAYCE U.S.$57.7M—78.7%
- ARIKAYCE International$15.6M—21.3%
Forward guidance
Insmed anticipates continued revenue growth in 2025, driven by the expansion of ARIKAYCE and the potential U.S. launch of brensocatib.
Tailwinds
- ARIKAYCE revenue guidance for 2025 set between $405 million and $425 million.
- Brensocatib NDA accepted by the FDA with a priority review and target action date of August 12, 2025.
- Phase 2b and Phase 3 studies on track with expected topline data in 2025 and early 2026.
- Strong cash position of $1.4 billion provides financial flexibility for expansion.
- Continued pipeline development with upcoming regulatory submissions in the EU, UK, and Japan.
Headwinds
- Net losses continue to widen due to high R&D and SG&A expenses.
- Regulatory risks remain for brensocatib approval and commercial success.
- Increased operational costs expected with upcoming U.S. launch preparations.
- Dependency on ARIKAYCE revenue growth to fund expansion initiatives.
- Global economic uncertainties could impact pricing and reimbursement strategies.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2024
-1.2%
Avg return
Earnings day
-0.2%
Avg return
5 days after
+1.8%
Avg return
30 days after
35%
23 / 65 earnings
Positive
+27.5%
Q2 2022
Best reaction
-23.3%
Q1 2026
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -23.3% | -15.4% | -31.3% | |
| Q4 2025 | +6.3% | +5.0% | -10.0% | |
| Q3 2025 | +16.3% | +9.5% | +24.5% | |
| Q1 2025 | -4.0% | -3.8% | +7.8% | |
| Q4 2024 | -0.3% | -7.6% | -4.7% | |
| Q3 2024 | -2.8% | -1.4% | +6.9% | |
| Q2 2024 | +4.2% | +7.6% | +0.1% | |
| Q1 2024 | -0.1% | -2.1% | +118.7% | |
| Q4 2023 | -3.4% | +3.5% | -6.4% | |
| Q3 2023 | -6.2% | -1.5% | -5.6% | |
| Q2 2023 | +1.0% | +1.3% | +4.0% | |
| Q1 2023 | -2.0% | -4.4% | -1.3% | |
| Q4 2022 | -3.9% | -2.4% | -21.2% | |
| Q3 2022 | -1.1% | -1.2% | +4.0% | |
| Q2 2022 | +27.5% | +26.6% | +12.8% | |
| Q1 2022 | -9.9% | -19.6% | -14.5% | |
| Q4 2021 | -5.2% | -6.5% | +0.9% | |
| Q3 2021 | +14.2% | +21.3% | +9.6% | |
| Q2 2021 | +3.4% | -2.3% | +15.1% | |
| Q1 2021 | +6.7% | -11.7% | -17.0% | |
| Q4 2020 | -10.6% | -3.9% | -13.4% | |
| Q3 2020 | -6.4% | -6.8% | +13.1% | |
| Q2 2020 | +14.8% | +7.9% | +2.5% | |
| Q1 2020 | +6.5% | +13.4% | +15.4% | |
| Q4 2019 | -11.8% | -16.6% | -38.0% | |
| Q3 2019 | +10.4% | +16.6% | +36.9% | |
| Q2 2019 | -20.7% | -22.5% | -25.1% | |
| Q1 2019 | -11.7% | -11.5% | -27.8% | |
| Q4 2018 | +14.3% | +17.0% | +10.3% | |
| Q3 2018 | -4.2% | +7.2% | +15.0% | |
| Q2 2018 | +5.6% | -1.6% | -19.5% | |
| Q1 2018 | +3.9% | +2.0% | +13.9% | |
| Q4 2017 | +8.1% | -0.8% | -11.1% | |
| Q3 2017 | +10.3% | +10.8% | +13.9% | |
| Q2 2017 | -8.6% | -17.2% | -20.7% | |
| Q1 2017 | -3.2% | -7.4% | -15.6% | |
| Q4 2016 | -1.1% | +9.5% | +8.7% | |
| Q3 2016 | -6.7% | +0.8% | +4.7% | |
| Q2 2016 | -0.2% | +0.3% | +13.4% | |
| Q1 2016 | +0.4% | — | — | |
| Q4 2015 | -2.3% | — | — | |
| Q3 2015 | -20.0% | — | — | |
| Q2 2015 | -2.4% | — | — | |
| Q1 2015 | +5.6% | — | — | |
| Q4 2014 | +3.4% | — | — | |
| Q3 2014 | -0.4% | — | — | |
| Q2 2014 | -9.3% | — | — | |
| Q1 2014 | +5.2% | — | — | |
| Q4 2013 | -7.8% | — | — | |
| Q3 2013 | -1.8% | — | — | |
| Q2 2013 | -2.8% | — | — | |
| Q1 2013 | -5.0% | — | — | |
| Q4 2012 | +5.5% | — | — | |
| Q3 2012 | +4.8% | — | — | |
| Q2 2012 | -6.8% | — | — | |
| Q1 2012 | -19.5% | — | — | |
| Q4 2009 | -0.3% | — | — | |
| Q4 2011 | -0.3% | — | — | |
| Q3 2011 | -3.7% | — | — | |
| Q2 2011 | -4.7% | — | — | |
| Q4 2010 | -4.7% | — | — | |
| Q1 2011 | -6.4% | — | — | |
| Q3 2010 | +4.1% | — | — | |
| Q2 2010 | -1.9% | — | — | |
| Q1 2010 | -12.7% | — | — |
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