NASDAQ$INSM

Insmed Incorporated · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Insmed reported strong Q4 2023 financial results, marked by arikace revenue growth and pipeline advancement.

Insmed reported Q4 2023 total revenue of $83.7 million, a 41% increase compared to Q4 2022. The company's net loss for the quarter was $186.1 million, or $1.28 per share. Insmed ended the year with $780.4 million in cash, cash equivalents, and marketable securities.

  • Total revenue for the fourth quarter ended December 31, 2023, was $83.7 million, reflecting 41% growth compared to total revenue of $59.3 million for the fourth quarter of 2022.
  • Insmed reported a net loss of $186.1 million, or $1.28 per share, compared to a net loss of $160.1 million, or $1.21 per share, for the fourth-quarter 2022.
  • As of December 31, 2023, Insmed had cash, cash equivalents, and marketable securities totaling $780.4 million.
  • Insmed is reiterating its sales guidance for full-year 2024 global ARIKAYCE revenues in the range of $340 million to $360 million, representing 15% year-over-year growth at the midpoint compared to 2023.

Headline financials

Total Revenue

$83.7M

Previous: $59.3M+41.1%
EPS (adj)

-$1.28

Previous: -$1.21-5.8%
Capital Expenditures

-$2.15M

Previous: $4.69M-145.9%
Net Income

-$186M

Previous: -$160M-16.2%
Operating Income

-$178M

Previous: -$151M-17.7%
Gross Profit

$65.3M

Previous: $46.2M+41.1%
R&D Expense

$137M

No prior period
Stock-Based Comp

$20M

Previous: $15M+33.7%

Revenue & EPS history

Insmed · Revenue · Quarterly

$83.7M

Q4 2023+41.1%vs Q4 2022
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Insmed · $73.3M total across 2 segments · Q2 2023

  • ARIKAYCE U.S.
    $57.7M
  • ARIKAYCE International
    $15.6M

Forward guidance

Insmed is reiterating its sales guidance for full-year 2024 global ARIKAYCE revenues in the range of $340 million to $360 million, representing 15% year-over-year growth at the midpoint compared to 2023.

Tailwinds

  • Commercialization and expansion of ARIKAYCE globally.
  • Advancement of brensocatib, including the Phase 3 ASPEN study in patients with bronchiectasis, and commercial launch readiness activities, the ongoing Phase 2 trial in patients with CRSsNP, and the Phase 2 program in HS to be initiated in the second half of the year if the ASPEN result is positive.
  • Advancement of the clinical trial program for ARIKAYCE, which is intended to satisfy the post-marketing requirement for full approval of its current indication and potentially support label expansion to include all patients with a MAC lung infection.
  • Advancement of its Phase 2 clinical development programs for TPIP.
  • Development of its early-stage research programs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-1.2%

Avg return

Earnings day

-0.2%

Avg return

5 days after

+1.8%

Avg return

30 days after

35%

23 / 65 earnings

Positive

+27.5%

Q2 2022

Best reaction

-23.3%

Q1 2026

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-23.3%-15.4%-31.3%
Q4 2025+6.3%+5.0%-10.0%
Q3 2025+16.3%+9.5%+24.5%
Q1 2025-4.0%-3.8%+7.8%
Q4 2024-0.3%-7.6%-4.7%
Q3 2024-2.8%-1.4%+6.9%
Q2 2024+4.2%+7.6%+0.1%
Q1 2024-0.1%-2.1%+118.7%
Q4 2023-3.4%+3.5%-6.4%
Q3 2023-6.2%-1.5%-5.6%
Q2 2023+1.0%+1.3%+4.0%
Q1 2023-2.0%-4.4%-1.3%
Q4 2022-3.9%-2.4%-21.2%
Q3 2022-1.1%-1.2%+4.0%
Q2 2022+27.5%+26.6%+12.8%
Q1 2022-9.9%-19.6%-14.5%
Q4 2021-5.2%-6.5%+0.9%
Q3 2021+14.2%+21.3%+9.6%
Q2 2021+3.4%-2.3%+15.1%
Q1 2021+6.7%-11.7%-17.0%
Q4 2020-10.6%-3.9%-13.4%
Q3 2020-6.4%-6.8%+13.1%
Q2 2020+14.8%+7.9%+2.5%
Q1 2020+6.5%+13.4%+15.4%
Q4 2019-11.8%-16.6%-38.0%
Q3 2019+10.4%+16.6%+36.9%
Q2 2019-20.7%-22.5%-25.1%
Q1 2019-11.7%-11.5%-27.8%
Q4 2018+14.3%+17.0%+10.3%
Q3 2018-4.2%+7.2%+15.0%
Q2 2018+5.6%-1.6%-19.5%
Q1 2018+3.9%+2.0%+13.9%
Q4 2017+8.1%-0.8%-11.1%
Q3 2017+10.3%+10.8%+13.9%
Q2 2017-8.6%-17.2%-20.7%
Q1 2017-3.2%-7.4%-15.6%
Q4 2016-1.1%+9.5%+8.7%
Q3 2016-6.7%+0.8%+4.7%
Q2 2016-0.2%+0.3%+13.4%
Q1 2016+0.4%
Q4 2015-2.3%
Q3 2015-20.0%
Q2 2015-2.4%
Q1 2015+5.6%
Q4 2014+3.4%
Q3 2014-0.4%
Q2 2014-9.3%
Q1 2014+5.2%
Q4 2013-7.8%
Q3 2013-1.8%
Q2 2013-2.8%
Q1 2013-5.0%
Q4 2012+5.5%
Q3 2012+4.8%
Q2 2012-6.8%
Q1 2012-19.5%
Q4 2009-0.3%
Q4 2011-0.3%
Q3 2011-3.7%
Q2 2011-4.7%
Q4 2010-4.7%
Q1 2011-6.4%
Q3 2010+4.1%
Q2 2010-1.9%
Q1 2010-12.7%

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