NASDAQ$CRBU

Caribou Biosciences Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Reported fourth quarter and full year 2022 financial results and provided a business update.

Caribou Biosciences reported financial results for the fourth quarter and full year 2022 and reviewed recent pipeline progress. The company had $317.0 million in cash, cash equivalents, and marketable securities as of December 31, 2022, and expects these funds to be sufficient to fund its current operating plan into 2025.

  • CB-010 ANTLER Phase 1 trial in r/r B-NHL is ongoing with an update planned for H2 2023.
  • CB-011 CaMMouflage Phase 1 trial in r/r MM is recruiting patients at dose level 1.
  • CB-012 IND-enabling studies have been initiated, with an IND submission in r/r AML planned for H2 2023.
  • The company had $317.0 million in cash, cash equivalents, and marketable securities as of December 31, 2022, providing a cash runway to fund the current operating plan into 2025.

Headline financials

Total Revenue

$3.69M

Previous: $2.56M+44.3%
EPS (adj)

-$0.44

Previous: -$0.31-41.9%
Capital Expenditures

$1.76M

Previous: $685K+156.5%
Free Cash Flow

-$26.8M

Previous: -$22.1M-21.4%
Net Income

-$27M

Previous: -$18.5M-46.1%
Operating Income

-$30.6M

Previous: -$20.4M-49.9%
Gross Profit

$2.79M

Previous: $2.29M+22.0%
Cash & Equivalents

$317M

Previous: $414M-23.3%
Total Assets

$374M

Previous: $442M-15.5%
Stock-Based Comp

$3.1M

Previous: $1.58M+96.5%

Revenue & EPS history

Caribou Biosciences · Revenue · Quarterly

$3.69M

Q4 2022+44.3%vs Q4 2021
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Caribou Biosciences · $3.76M total across 1 segment · Q2 2023

  • Licensing & collaboration
    $3.76M-10.6%

Forward guidance

Caribou plans to maintain momentum by advancing two ongoing clinical trials for off-the-shelf cell therapies in patients with hematologic malignancies and preparing an IND submission for its third program, CB-012.

Tailwinds

  • CB-010: Provide an update from the ongoing ANTLER Phase 1 trial for CB-010 in H2 2023.
  • CB-011: Provide an update on the clearance of dose levels as appropriate from the CaMMouflage Phase 1 trial for CB-011.
  • CB-012: Submit an IND application for CB-012 in H2 2023.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-0.8%

Avg return

Earnings day

+0.9%

Avg return

5 days after

-5.2%

Avg return

30 days after

53%

10 / 19 earnings

Positive

+11.1%

Q2 2021

Best reaction

-32.3%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.1%+4.1%-1.5%
Q4 2025+6.5%+15.2%+13.5%
Q3 2025-12.1%-17.3%-20.8%
Q1 2025+10.5%+16.7%+19.4%
Q4 2024+0.1%-8.6%-22.2%
Q3 2024+8.6%+9.0%-16.8%
Q2 2024-3.1%-0.8%-6.4%
Q1 2024-8.6%-7.6%-45.4%
Q4 2023-32.3%-27.6%-41.4%
Q3 2023-5.0%-19.3%+24.7%
Q2 2023+5.2%+5.8%-12.0%
Q1 2023+9.3%-2.1%+4.0%
Q4 2022-11.8%-11.4%-9.9%
Q3 2022+3.9%+15.0%+2.4%
Q2 2022+10.1%+17.3%+40.7%
Q1 2022-0.5%+22.4%+23.7%
Q4 2021+2.6%-5.6%-16.1%
Q3 2021-4.9%-0.5%-18.2%
Q2 2021+11.1%+12.3%-17.3%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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