NASDAQ$CRBU

Caribou Biosciences Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Caribou Biosciences reported financial results for the first quarter of 2023 and reviewed recent pipeline progress.

Caribou Biosciences reported a net loss of $28.0 million for the first quarter of 2023, with $291.0 million in cash, cash equivalents, and marketable securities as of March 31, 2023. The company is advancing its pipeline of allogeneic CAR-T cell therapies, including the ongoing ANTLER trial for CB-010 and the initiation of patient dosing in the CaMMouflage trial for CB-011.

  • CB-010 ANTLER Phase 1 trial enrolling second-line LBCL patients in dose expansion; plan to report dose escalation data in H2 2023
  • CB-011 CaMMouflage Phase 1 trial enrolling r/r MM patients at dose level 1
  • CB-012 IND application for r/r AML planned for H2 2023
  • $291.0 million in cash, cash equivalents, and marketable securities as of March 31, 2023; cash runway to fund the current operating plan into 2025

Headline financials

Total Revenue

$3.5M

Previous: $2.66M+31.5%
EPS (adj)

-$0.46

Previous: -$0.32-43.8%
Capital Expenditures

-$2.03M

Previous: -$723K-180.9%
Free Cash Flow

-$30.1M

Previous: -$19.8M-51.8%
Net Income

-$28M

Previous: -$19.1M-46.9%
Operating Income

-$31.1M

Previous: -$20.9M-49.2%
Gross Profit

$2.4M

Previous: $1.86M+29.2%
Cash & Equivalents

$291M

Previous: $148M+97.1%
Total Assets

$347M

Previous: $446M-22.1%
Stock-Based Comp

$3.13M

Previous: $3.02M+3.5%

Revenue & EPS history

Caribou Biosciences · Revenue · Quarterly

$3.5M

Q1 2023+31.5%vs Q1 2022
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Caribou Biosciences · $3.76M total across 1 segment · Q2 2023

  • Licensing & collaboration
    $3.76M-10.6%

Forward guidance

Caribou anticipates several milestones in 2023, including providing a safety and efficacy update from the ANTLER Phase 1 clinical trial for CB-010 in H2 2023, providing updates on dose escalation as the CaMMouflage Phase 1 clinical trial for CB-011 advances, and submitting an IND application for CB-012 in H2 2023.

Tailwinds

  • CB-010: Caribou plans to provide a safety and efficacy update in H2 2023 from the ongoing ANTLER Phase 1 clinical trial in r/r B-NHL, including data from at least 15 patients from dose escalation with a minimum of six months follow up.
  • CB-011: Caribou plans to provide updates on dose escalation as the CaMMouflage Phase 1 clinical trial in r/r MM advances.
  • CB-012: Caribou plans to submit an IND application for r/r AML in H2 2023.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

-0.8%

Avg return

Earnings day

+0.9%

Avg return

5 days after

-5.2%

Avg return

30 days after

53%

10 / 19 earnings

Positive

+11.1%

Q2 2021

Best reaction

-32.3%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.1%+4.1%-1.5%
Q4 2025+6.5%+15.2%+13.5%
Q3 2025-12.1%-17.3%-20.8%
Q1 2025+10.5%+16.7%+19.4%
Q4 2024+0.1%-8.6%-22.2%
Q3 2024+8.6%+9.0%-16.8%
Q2 2024-3.1%-0.8%-6.4%
Q1 2024-8.6%-7.6%-45.4%
Q4 2023-32.3%-27.6%-41.4%
Q3 2023-5.0%-19.3%+24.7%
Q2 2023+5.2%+5.8%-12.0%
Q1 2023+9.3%-2.1%+4.0%
Q4 2022-11.8%-11.4%-9.9%
Q3 2022+3.9%+15.0%+2.4%
Q2 2022+10.1%+17.3%+40.7%
Q1 2022-0.5%+22.4%+23.7%
Q4 2021+2.6%-5.6%-16.1%
Q3 2021-4.9%-0.5%-18.2%
Q2 2021+11.1%+12.3%-17.3%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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