NASDAQ$CRBU

Caribou Biosciences Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Caribou Biosciences reported financial results for the first quarter of 2022 and provided business updates.

Caribou Biosciences reported a net loss of $19.1 million for the first quarter of 2022, compared to a net loss of $13.2 million for the same period in 2021. The company's cash, cash equivalents, and marketable securities totaled $390.8 million as of March 31, 2022.

  • Initial ANTLER Phase 1 clinical data is scheduled to be shared at the European Hematology Association (EHA) 2022 Hybrid Congress for CB-010 in patients with r/r B-NHL.
  • Submission of IND application planned in H2 2022 for CB-011 for evaluation in patients with r/r multiple myeloma.
  • Caribou had $390.8 million in cash, cash equivalents, and marketable securities as of March 31, 2022.
  • Caribou expects to announce target selection for CB-020 in Q4 2022.

Headline financials

Total Revenue

$2.66M

Previous: $1.59M+68.0%
EPS (adj)

-$0.32

Previous: -$0.48+32.7%
Capital Expenditures

-$723K

No prior period
Free Cash Flow

-$19.8M

No prior period
Net Income

-$19.1M

Previous: -$13.2M-45.1%
Operating Income

-$20.9M

Previous: -$13.2M-58.3%
Gross Profit

$1.86M

Previous: -$8.58M+121.6%
Cash & Equivalents

$148M

No prior period
Total Assets

$446M

No prior period
Stock-Based Comp

$3.02M

No prior period

Revenue & EPS history

Caribou Biosciences · Revenue · Quarterly

$2.66M

Q1 2022+68%vs Q1 2021
Beat estimate in 5 of 10 quarters(50%)
ActualEstimate

Revenue by segment

Caribou Biosciences · $2.66M total across 1 segment · Q1 2022

  • Licensing & collaboration
    $2.66M+68.0%

Forward guidance

Caribou anticipates several milestones for 2022 and beyond, focusing on clinical data releases, IND application submissions, and target selection announcements for their allogeneic CAR-T and CAR-NK cell therapies.

Tailwinds

  • CB-010: Scheduled to share initial data from its ongoing ANTLER Phase 1 trial at EHA in June 2022.
  • CB-011: Expects to submit an IND application in H2 2022.
  • CB-020: Expects to announce target selection in Q4 2022.
  • CB-012: Expects to submit an IND application in 2023.
  • Presents poster highlighting the mechanism underlying the superior specificity of its CRISPR hybrid RNA-DNA (chRDNA) guides for genome editing of primary human T cells on May 16, 2022

Headwinds

  • Risks inherent in the development of cell therapy products.
  • Uncertainties related to the initiation, cost, timing, progress, and results of current and future research and development programs, preclinical studies, and clinical trials.
  • Risk that initial or interim clinical trial data will not be predictive of the safety and efficacy of Caribou’s product candidates.
  • Clinical outcomes may differ as more patient data becomes available.
  • Reliance on forward-looking statements as predictions of future events.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-0.8%

Avg return

Earnings day

+0.9%

Avg return

5 days after

-5.2%

Avg return

30 days after

53%

10 / 19 earnings

Positive

+11.1%

Q2 2021

Best reaction

-32.3%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.1%+4.1%-1.5%
Q4 2025+6.5%+15.2%+13.5%
Q3 2025-12.1%-17.3%-20.8%
Q1 2025+10.5%+16.7%+19.4%
Q4 2024+0.1%-8.6%-22.2%
Q3 2024+8.6%+9.0%-16.8%
Q2 2024-3.1%-0.8%-6.4%
Q1 2024-8.6%-7.6%-45.4%
Q4 2023-32.3%-27.6%-41.4%
Q3 2023-5.0%-19.3%+24.7%
Q2 2023+5.2%+5.8%-12.0%
Q1 2023+9.3%-2.1%+4.0%
Q4 2022-11.8%-11.4%-9.9%
Q3 2022+3.9%+15.0%+2.4%
Q2 2022+10.1%+17.3%+40.7%
Q1 2022-0.5%+22.4%+23.7%
Q4 2021+2.6%-5.6%-16.1%
Q3 2021-4.9%-0.5%-18.2%
Q2 2021+11.1%+12.3%-17.3%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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