NASDAQ$CRBU

Caribou Biosciences Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Reported financial results for the third quarter of 2022 and provided a business update.

Caribou Biosciences reported promising results from its lead allogeneic cell therapy, CB-010, in the ANTLER clinical trial and submitted an IND application for CB-011. The company's financial position remains strong with $342.6 million in cash, cash equivalents, and marketable securities.

  • CB-010 ANTLER Phase 1 trial in r/r B-NHL is advancing, with additional data from cohort 1 expected by YE 2022.
  • CB-011 IND application for r/r MM was submitted to the FDA in Q4 2022.
  • The company has a strong financial position with $342.6 million in cash, cash equivalents, and marketable securities as of September 30, 2022.
  • 6 of 6 patients (100%) achieved a CR as their best response; 3 of 6 patients (50%) maintained a CR at 6 months

Headline financials

Total Revenue

$3.3M

Previous: $3.98M-16.9%
EPS (adj)

-$0.44

Previous: -$0.46+4.3%
R&D expenses

$20M

No prior period
G&A expenses

$9.85M

No prior period
Capital Expenditures

-$4.7M

Previous: -$1.44M-227.1%
Free Cash Flow

-$31.3M

Previous: -$22.4M-39.9%
Net Income

-$26.6M

Previous: -$21M-27.0%
Operating Income

-$26.5M

Previous: -$18.6M-42.5%
Gross Profit

$2.23M

Previous: -$11.9M+118.8%
Cash & Equivalents

$82.1M

Previous: $435M-81.1%
Total Assets

$399M

Previous: $462M-13.7%
Stock-Based Comp

$2.67M

Previous: $935K+185.9%

Revenue & EPS history

Caribou Biosciences · Revenue · Quarterly

$3.3M

Q3 2022-16.9%vs Q3 2021
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Caribou Biosciences · $3.3M total across 1 segment · Q3 2022

  • Licensing & collaboration
    $3.3M-16.9%

Forward guidance

Caribou anticipates several milestones in the fourth quarter of 2022 and beyond, including data releases and regulatory responses.

Tailwinds

  • Caribou plans to share additional data from cohort 1 of the ongoing ANTLER Phase 1 trial for CB-010 by YE 2022.
  • Caribou anticipates the FDA’s response to Caribou’s IND application for CB-011 by YE 2022.
  • Caribou expects to announce target selection for CB-020 in Q4 2022.
  • Caribou expects to disclose armoring strategies under development for its CAR-NK cell platform in Q4 2022.
  • Caribou expects to submit an IND application for CB-012 in 2023.

Headwinds

  • Risks related to our limited operating history.
  • History of net operating losses.
  • Financial position and our ability to raise additional capital as needed to fund our operations and product candidate development.
  • Risks inherent in development of cell therapy products.
  • Uncertainties related to the initiation, cost, timing, progress, and results of current and future research and development programs, preclinical studies, and clinical trials.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

-0.8%

Avg return

Earnings day

+0.9%

Avg return

5 days after

-5.2%

Avg return

30 days after

53%

10 / 19 earnings

Positive

+11.1%

Q2 2021

Best reaction

-32.3%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.1%+4.1%-1.5%
Q4 2025+6.5%+15.2%+13.5%
Q3 2025-12.1%-17.3%-20.8%
Q1 2025+10.5%+16.7%+19.4%
Q4 2024+0.1%-8.6%-22.2%
Q3 2024+8.6%+9.0%-16.8%
Q2 2024-3.1%-0.8%-6.4%
Q1 2024-8.6%-7.6%-45.4%
Q4 2023-32.3%-27.6%-41.4%
Q3 2023-5.0%-19.3%+24.7%
Q2 2023+5.2%+5.8%-12.0%
Q1 2023+9.3%-2.1%+4.0%
Q4 2022-11.8%-11.4%-9.9%
Q3 2022+3.9%+15.0%+2.4%
Q2 2022+10.1%+17.3%+40.7%
Q1 2022-0.5%+22.4%+23.7%
Q4 2021+2.6%-5.6%-16.1%
Q3 2021-4.9%-0.5%-18.2%
Q2 2021+11.1%+12.3%-17.3%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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